The exploration of submarine fan in the Meishan Formation of the Qiongdongnan basin has faced many challenges such as hydrocarbon source, migration pathway and trap effectiveness evaluation. Using a comparison of regional oil- gas- rock geochemical indexes, description of source- convergence- lithologic traps and analysis of reservoir forming dynamics, the dominant migration- accumulation areas and favorable exploration targets of submarine fan in the Meishan Formation are identified. The results show that the natural gas discovered in the Meishan Formation of the Ledong- Lingshui sag mainly originates from the terrigenous marine source rocks of the Yacheng Formation located near the concave slope area.The first member of the Meishan Formation has a large scale submarine fan reservoir with moderate sand- mud ratio of distal fan which is conducive to the formation of lithologic traps.Based on the differences of oil and gas geochemical characteristics and migration- accumulation conditions in different zones,two kind model of natural gas in the Meishan Formation are established respectively named “high efficient accumulation” and “limited accumulation”, indicating that the coupling of “transport ridge in source+high pressure fracture” is a necessary condition for the formation of gas field in the Meishan Formation. It is suggested that the submarine fans in the Meishan Formation and the Yinggehai Formation around the canyon of X25 area are favorable areas for further exploration.