Granite topology is defined as the search for the regional petrogenesis of granite and the relationships with its tectonic setting. Within the geological context, the criteria of some petrological, mineralogical and geochemi-cal paragenetic associations which are closely in connection with its emplacement and textural and structural e-volving patterns can bodily be considered as a main theme to elucidate the natural system containing both the source region and the evolving processes of granite, and highlight upon the linkage with the tectonic stage of a tectonic cycle during its formation. It can also be suggested as the build-up of the observed modellings of the transmission of heat flow of magma genesis in prospect.Granite petrogenesis with multifactorial generative processes is intrinsically in connection with the mechanism of transfer of heat flow such as conduction, convection and advection through crustal-mantle interaction, the thermal purturbation and relaxation of which are intimately connected with their tectonic disturbances. Accordingly, granite topology emphasizes the tectonic constraints and forms a main theme with criteria of some petrological, mineralogical, and geochemical paragenetic associations as principal and in connection with their emplancement and textural, structural evolving patterns as a trinity as the build-up of the regional petrogeneis.The petrological, mineralogical and geochemical paragenetic associations can bodily reflect the thermody-namic behavior of the natural system that contains both the source region and processes. Although the associations behave as different entities operating as different functions within the system, but they are closely interconnected , even overlapped, and cannot be treated solely instead of their integrated attacks. In general, the elemental abundances and the mineral phases can be matched with the components and phases of the system. Theoretically, a topological treatment within a rigorous thermodynamic constraints of a chemical system such as (KNCASH) can be applied to a granite series to formulate matrices array in order to solve the thermodynamic processes which are desirable in depicting observed modellings within the heat flow regime.