Tiandong tungsten-tin polymetallic deposit is located at the northeast of Lianhuashan fault zone in the east of Guangdong Province, which has different kinds of granite. As the study examples of three kinds of granite in Tiandong tungsten-tin polymetallic deposit, we performed in situ zircon U-Pb dating and Hf isotopic analyses for the first time. Three kinds of granite consist of medium-grained granite, coarse granite, fine-grained biotite granite, which the wighted average 206Pb/238U ages are 191.5±0.9Ma, 158.0±1.3Ma, 140.5±0.8Ma. Therefore, it indicats that the Tiandong area has gone through three magmatic events which ouccured in Early-Jurassic, Middle-Jurassic and Tiandong tungsten-tin polymetallic deposit is located at the northeast of Lianhuashan fault zone in the east of Guangdong Province, which has different kinds of granite. As the study examples of three kinds of granite in Tiandong tungsten-tin polymetallic deposit, we performed in situ zircon U-Pb dating and Hf isotopic analyses for the first time. Three kinds of granite consist of medium-grained granite, coarse granite, fine-grained biotite granite, which the wighted average 206Pb/238U ages are 191.5±0.9Ma, 158.0±1.3Ma, 140.5±0.8Ma. Therefore, it indicats that the Tiandong area has gone through three magmatic events which ouccured in Early-Jurassic, Middle-Jurassic and Early-Cretaceous, respectively. εHf (t) values of medium-grained granite have a range of 4.023~9.784, and the mean is 7.644. On the εHf (t) versus age diagram, εHf (t) are above the evolution curve of chondrite and below the evolution curve of depleted mantle. Moreover, the age of stage( tDM2) is 611.0~974.9Ma, indicating that rock-forming materials mainly derived from the juvenile crustal partial melting. εHf (t) values of coarse granite have a range of -3.623~-0.120, and the mean is -1.680. εHf (t) values of fine-grained biotite granite have a range of -5.358~-1.609, and the mean is -3.577. On the εHf (t) versus age diagram, εHf (t) values of coarse granite and fine-grained biotite granite are all above the evolution curve of ancient proterozoic crustal and below the evolution curve of chondrite. Moreover, the ages of stage( tDM2) are respectively 1216.6~1438.5Ma and 1329.9~1422.5Ma，indicating that rock-forming materials mainly derived from the ancient proterozoic crustal partial melting and mantle material.