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基于BSA及固定碘速率探讨不同浓度对比剂对肝静脉CT成像效果的影响
引用本文:董相宇,方挺松,袁健祥,梁振华,李均洪.基于BSA及固定碘速率探讨不同浓度对比剂对肝静脉CT成像效果的影响[J].CT理论与应用研究,2021,30(4):466-476.
作者姓名:董相宇  方挺松  袁健祥  梁振华  李均洪
作者单位:广州中医药大学附属佛山中医院放射科, 广东佛山 528000
基金项目:佛山市十三五重点专科项目(FSZDZK135017);佛山市重点专科培育项目(Fspy3-2015019)。
摘    要:目的:探讨基于体表面积(BSA)和固定碘速率给药,不同浓度对比剂对CT肝静脉成像质量的影响。方法:选取2020年1月至11月符合纳入标准,行上腹部增强CT扫描的患者130例,根据所用对比剂浓度不同,分为高浓度组(62例)和低浓度组(68例),高浓度组对比剂为碘帕醇(含碘370mg/mL),低浓度组对比剂为碘佛醇(含碘320mg/mL);根据BSA计算患者所用对比剂的总量,固定碘速率注射,进行分期动态扫描。选取肝静脉期数据行肝静脉血管重建,对图像质量进行评价,测量两组图像肝静脉和肝实质的CT值及其标准差值,计算信噪比和对比噪声比,并对图像质量进行主观评分;采用独立样本t检验比较两组间客观评价指标的差异,采用Mann-Whitney U检验比较主观评分的差异。结果:高、低浓度组图像评分分别为(3.74±0.47)分和(3.77±0.53)分,差异无统计学意义;两组间肝静脉左、中、右三支主干和同层面肝实质的CT值、SD值、SNR及肝静脉相对于肝实质的CNR,差异无统计学意义。结论:基于BSA及固定碘速率注射对比剂,两种不同浓度对比剂在肝静脉CT成像中的效果同样清晰利于诊断。 

关 键 词:体表面积    对比剂浓度    肝静脉    多层螺旋CT
收稿时间:2021-01-04

Discussion on the Effect of Different Concentrations of Contrast Media on CT Imaging of Hepatic Veins Based on BSA and Fixed Iodine Rate
DONG Xiangyu,FANG Tingsong,YUAN Jianxiang,LIANG Zhenhua,LI Junhong.Discussion on the Effect of Different Concentrations of Contrast Media on CT Imaging of Hepatic Veins Based on BSA and Fixed Iodine Rate[J].Computerized Tomography Theory and Applications,2021,30(4):466-476.
Authors:DONG Xiangyu  FANG Tingsong  YUAN Jianxiang  LIANG Zhenhua  LI Junhong
Affiliation:Department of Radiology, Foshan TCM Hospital of Guangzhou University of Chinese Medicine, Foshan 528000, China
Abstract:Objective: To explore the effects of different concentrations of contrast agents on the quality of CT hepatic venous imaging based on body surface area (BSA) and fixed iodine rate administration. Method: According to the inclusion criteria, 130 patients were selected and received enhanced upper abdominal CT scan from January to November 2020. According to the different contrast agents, they were divided into high concentration group (62 cases) and low concentration group (68 cases). The contrast agent of the high concentration group was iopamidol (containing iodine 370mg/mL), and the contrast agent of the low concentration group was ioversol (containing iodine 320mg/mL). To calculate the total amount of iodine based on BSA. fixed iodine rate administration, and triple-phase enhanced CT scans. Hepatic vein phase data were selected for reconstruction of hepatic vein vessels, and image quality was evaluated. CT values and standard deviations of hepatic vein and liver parenchyma of the two groups of images were measured. Signal-to-noise ratio (SNR) and contrastive noise ratio (CNR) were calculated, and image quality was evaluated subjectively. The independent sample t test was used to compare the differences in objective evaluation indicators between the two groups, and the Mann-Whitney U test was used to compare the differences in subjective scores. Results: The image scores of high and low concentration groups were (3.74±0.47) points and (3.77±0.53) points, respectively, with no statistical significance; There were no significant differences in CT values, SD values, SNR values of the left, middle and right branches of hepatic vein and liver parenchyma at the same level between the two groups. Conclusion: Based on BSA and fixed iodine rate injection contrast agent, the effect of two different concentrations of contrast agent in hepatic venous CT imaging is equally clear and conducive to diagnosis. 
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