Abstract: The Shierzhan intrusion, located in the Great Xing'an Range of northeastern China, is mainly composed of syenogranite and monzogranite. Zircon U-Pb age obtained by LA-ICP-MS analyses from the syenogranite is 298Ma, suggesting that it is the result of Late Paleozoic magmatic activities. Petrochemically, the Shierzhan granite is characterized by high K (K2O 4.82%~6.06%), and therefore belongs to shoshonite series. It is enriched in LILE (LREE, Rb, Th, and K) and depleted in HFSE (Nb, Ta, P, and Ti), showing characteristics of post-orogenic granites. It is proposed that this pluton was likely the product of post-orogenic evolution after the collision of Xing'an and Songnen massifs. Zircon Hf isotopic data of the granite suggest that crustal growth of Xing'an massif in northern Great Xing'an Range occurred in the Phanerozoic, which is much different from that of the Eerguna massif which diaplayes crustal formation age of Neoprotozoic to Phanerozoic. Therefore, the Xing'an and Eerguna massifs have different early crustal evolution histories.