Abstract: It was introduced in this paper that some basic geological prospecting prediction theories include mineral deposit models, metallogenic series, metallogenic system, multi-genetic compounds of mineralization, geological abnormity, and the content and developing trend of the model prediction method, as well as the performance characteristics and their application in concealed ore-deposit prediction about new technologies and methods of geophysical and geochemical prospecting. Meanwhile, some new technologies and methods , such as mathematical geology, geographic information systems (GIS)，and quantitative evaluation of the effectiveness of prospecting technique method, were also briefly introduced in the paper.