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1.
目的：探讨真武汤合附子理中丸加减方对糖尿病肾病(DKD)脾肾阳虚证的临床疗效。方法：将120 例DKD脾肾阳虚证患者随机分为2组,每组各60例。对照组采用西医常规治疗,治疗组在对照组基础上加用真武汤合附子理中丸加减方治疗。比较2组治疗前后血糖水平［包括空腹血糖（FPG）、餐后2h血糖（2hPG）、糖化血红蛋白（HbA1c）］、肾功能指标［包括血肌酐（Scr）、血尿素氮(BUN)、24h尿蛋白定量、胱抑素 C（Cys-C）］及中医证候积分,评定2组综合疗效及中医证候疗效,观察不良反应情况。结果：综合疗效和中医证候疗效总有效率治疗组分别为83.33%（50/60）、91.67%（55/60）,对照组分别为75.00%（45/60）、78.33%（47/60）,2组比较,差异均有统计学意义（P＜0.05或P<0.01）。2组治疗后血糖及肾功能指标水平均较治疗前下降,中医证候积分较治疗前降低,且改善程度治疗组均优于对照组,差异均有统计学意义（P<0.05或P<0.01）。治疗组有1例患者出现轻微胃肠道反应,后自行缓解。2组治疗前后血压、心率、肝肾功能及血、尿常规等安全性指标比较,差异均无统计学意义（P>0.05）。结论：真武汤合附子理中丸加减方可有效缓解DKD脾肾阳虚证患者的临床症状,降低血糖水平及尿蛋白含量,保护肾脏功能,安全有效,值得临床推广应用。 相似文献
2.
目的：观察加减桂枝茯苓丸治疗湿热瘀阻型慢性放射性直肠炎的临床疗效。方法：将68 例慢性放射性直肠炎患者随机分为治疗组和对照组,每组各34 例。2组均予以对症支持治疗,对照组在此基础上予复方谷氨酰胺肠溶胶囊治疗,治疗组在对照组的基础上联合加减桂枝茯苓丸治疗,2组疗程均为14 d。观察2组综合疗效、中医证候积分、血清实验室指标［C反应蛋白（CRP）、肿瘤坏死因子-α（TNF-α）、白细胞介素-6（IL-6）］水平、Karnofsky功能状态（KPS）评分及不良反应等情况。结果：治疗期间治疗组剔除1 例,对照组剔除3 例,最终治疗组纳入33 例,对照组纳入31 例。总有效率治疗组为84.85%（28/33）,对照组为67.74%（21/31）,2组比较,差异有统计学意义（P<0.05）。2组中医证候积分、CRP、TNF-α、IL-6及KPS评分治疗前后组内比较及治疗后组间比较,差异均有统计学意义（P<0.05或P<0.01）。治疗期间2组均未出现不良反应。结论：加减桂枝茯苓丸联合西药治疗慢性放射性直肠炎疗效较好,可减轻患者肠道炎症反应,改善临床症状,提高患者生活质量,值得临床推广和应用。 相似文献
3.
目的：探究温阳解毒方联合隔药灸治疗糖尿病神经源性膀胱（DNB）阳虚毒郁证的临床疗效。方法：将52 例DNB阳虚毒郁证患者随机分为2组,每组各26 例。对照组予皮下注射胰岛素或口服降糖药控制血糖,治疗组在对照组基础上予温阳解毒方口服及隔药灸治疗,2组均治疗4周。比较2组治疗前和治疗2、4周后膀胱残余尿量（RUV）、中医证候积分和血糖水平［包括空腹血糖（FPG）、葡萄糖负荷后2h血糖（2hPG）］。结果：治疗组脱落1 例,对照组脱落3 例。2组治疗2周后的RUV、中医证候积分、FPG、2hPG及治疗组治疗4周后的RUV、中医证候积分与本组前一时间节点比较,差异均有统计学意义（P<0.01）;2组治疗2、4周后RUV、中医证候积分组间比较,差异均有统计学意义（P<0.05,P<0.01）,但FPG、2hPG组间比较,差异均无统计学意义（P>0.05）。2组治疗过程中均未出现明显不良反应。结论：温阳解毒方口服联合隔药灸能够有效治疗DNB阳虚毒郁证,可持续减少膀胱残余尿量,缓解临床症状。 相似文献
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目的：探讨丹栀逍遥散加减合甲巯咪唑片治疗甲状腺功能亢进症（甲亢）的临床效果。方法：将98 例甲亢患者随机分为治疗组和对照组,每组各49 例。治疗组采用丹栀逍遥散加减合甲巯咪唑片治疗,对照组单用甲巯咪唑片治疗。治疗4周后观察2组的综合疗效、中医证候积分、血清游离三碘甲状腺原氨酸（FT3）、血清游离甲状腺素（FT4）、促甲状腺素（TSH）及促甲状腺素受体抗体（TRAb）水平以及甲状腺肿胀程度。结果：总有效率治疗组为91.84%（45/49）,对照组为83.67%（41/49）,2组比较,差异有统计学意义（P＜0.05）。2组中医证候积分,FT3、FT4、TSH、TRAb水平以及甲状腺肿大程度评分治疗前后组内比较及治疗后组间比较,差异均有统计学意义（P＜0.05）。2组不良反应发生率比较,差异无统计学意义（P>0.05）。结论：应用丹栀逍遥散加减联合甲巯咪唑片治疗甲亢效果理想,值得临床推广应用。 相似文献
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目的：观察温胆汤合左金丸治疗慢性胃炎寒热错杂证的临床疗效。方法：将我院诊治的74 例慢性胃炎寒热错杂证患者随机分为治疗组和对照组,每组各37 例。2组均行常规治疗,对照组在常规治疗的基础上给予左金丸治疗,治疗组在对照组基础上再加温胆汤治疗。观察2组综合疗效、治疗前后中医证候积分、不良反应和复发情况。结果：总有效率治疗组为97.30%（36/37）,明显高于对照组的86.49%（32/37）,差异有统计学意义（P＜0.05）;2组中医证候积分治疗前后组内比较及治疗后组间比较,差异均有统计学意义（P＜0.05）;不良反应总发生率治疗组为5.40%（2/37）,优于对照组的18.92%（7/37）,差异均具有统计学意义（P＜0.05）。结论：温胆汤合左金丸治疗慢性胃炎寒热错杂证疗效明确,可改善其中医证候,减少不良反应和降低复发率。 相似文献
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目的：观察循经推拿联合定喘散穴位贴敷治疗小儿肺炎喘嗽的临床疗效。方法：将肺炎喘嗽患儿120 例随机分为观察组和对照组,每组各60 例。对照组采用定喘散穴位贴敷干预,观察组在对照组的基础上配合循经推拿干预。干预7 d后,观察2组综合疗效及咳嗽、咳痰、肺部啰音消失时间。结果：总有效率观察组为96.67%（58/60）,对照组为81.67%（49/60）,2组比较,差异有统计学意义（P＜0.01）;观察组咳嗽、咳痰、肺部啰音平均消失时间均较对照组短,差异均有统计学意义（P＜0.05或P＜0.01）。结论：循经推拿配合定喘散穴位贴敷能有效缩短肺炎喘嗽患儿的咳嗽、咳痰、肺部啰音消失时间,效果颇佳,值得临床推广应用。 相似文献
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目的：观察益气活血通络方加减治疗气虚血瘀型慢性萎缩性胃炎（CAG）的临床疗效。方法：将50 例气虚血瘀型CAG患者随机分为治疗组与对照组,每组各25 例。治疗组予以益气活血通络方加减治疗,对照组予以胃复春片治疗,均治疗3个月。观察2组患者的综合疗效、中医证候疗效及中医证候积分、胃镜评分、组织病理评分。结果：综合疗效总有效率治疗组为76.00%（19/25）,对照组为40.00%（10/25）,2组比较,差异有统计学意义（P<0.05）。中医证候疗效总有效率治疗组为100.00%（25/25）,对照组为76.00%（19/25）,2组比较,差异有统计学意义（P<0.01）。2组中医证候积分、胃镜评分、组织病理评分治疗前后组内比较及治疗后组间比较,差异均有统计学意义（P<0.01或P<0.05）。治疗组治疗后胃黏膜改善程度优于对照组（P<0.05）。结论：益气活血通络方加减治疗气虚血瘀型CAG疗效显著,能有效缓解患者症状,改善其内镜下表现及病理组织学表现。 相似文献
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目的：观察加味增液汤合针刺治疗气阴两虚型干眼症的临床疗效。方法：将60例辨证属气阴两虚型干眼症患者随机分为2组各30例，对照组采用人工泪液滴眼治疗，治疗组采用加味增液汤合针刺治疗。观察2组患者主要中医证候积分情况、泪液分泌量（SIt）、泪膜破裂时间（BUT），评价2组临床疗效。结果：总有效率治疗组为93.3%，对照组为76.7%，组间比较，差异有统计学意义（P<0.05）。2组中医证候积分、SIt、BUT治疗前后组内比较及治疗后组间比较，差异均有统计学意义（P<0.05）。结论：加味增液汤合针刺治疗气阴两虚型干眼症有较好疗效，较单纯应用人工泪液有明显优势。 相似文献
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目的：观察葶苓饮治疗慢性心力衰竭伴利尿剂抵抗的临床疗效。方法：将慢性心力衰竭伴利尿剂抵抗患者80 例随机分为治疗组和对照组,每组各40 例。对照组采用西医常规治疗,治疗组在对照组基础上加用葶苓饮治疗。观察2组治疗前后24h尿量、体质量、心功能指标（左室射血分数、B型纳尿肽前体）、电解质（血钠、血钾）、肾功能指标（血肌酐、尿酸）、Lee氏心衰积分、中医证候积分的变化,分别采用中医证候积分减少率、Lee氏心衰积分减少率评定中医证候疗效及综合疗效。结果：综合疗效总有效率治疗组为80.00%（32/40）,对照组为52.50%（21/40）,差异有统计学意义（P＜0.05）。中医证候疗效总有效率治疗组为85.00%（34/40）,对照组为62.50%（25/40）,差异有统计学意义（P＜0.05）。治疗后2组24h尿量、体质量、心功能指标均较治疗前改善,且治疗组优于对照组（均P<0.05）;治疗后2组血钾较治疗前均下降（P＜0.05）,但组间比较,差异无统计学意义（P＞0.05）,血钠、肾功能指标治疗前后组内比较及治疗后组间比较,差异均无统计学意义（P＞0.05）。结论：葶苓饮联合利尿剂能增加慢性心力衰竭伴利尿剂抵抗患者的24h尿量,改善心功能及临床症状,且安全性高。 相似文献
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目的:探讨柴胡桂枝干姜汤对原发性高血压病（EH）寒热错杂证患者中医证候积分及血管内皮功能的影响。方法：将106 例EH寒热错杂证患者随机为治疗组和对照组,每组各53 例。对照组采用苯磺酸氨氯地平片治疗,治疗组在对照组基础上加用柴胡桂枝干姜汤治疗。治疗3个月后,对比2组中医证候积分、血管内皮功能［一氧化氮（NO）、内皮素-1（ET-1）］及血压［收缩压（SBP）、舒张压（DBP）］水平。结果：与对照组比较,治疗组治疗后中医证候积分ET-1、SBP、DBP水平更低,NO水平更高,差异均有统计学意义（均P＜0.05）。结论：柴胡桂枝干姜汤能够降低EH寒热错杂证患者血压,改善中医证候和血管内皮功能。 相似文献
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This study presents an analytical solution for the problem of waves passing a submerged porous structure, using a multi-region method in the solution scheme considering the characteristics of geometry and composing materials of the porous structure. Using the flux and pressure conditions on horizontal boundaries and interfaces, the orthogonal property of wave motion within the porous layers through water depth is derived, and applied in the solution process. The flux and pressure conditions on vertical boundaries and interfaces are integrated to give a set of linear matrix equations, through which the unknown coefficients are solved. Comparisons of the present method with previous studies are preceded in verification, which suggests the validity and practicability of the present study, with a further expectation of extending our work to build a mild-slope equation over multiple-layer porous medium in the future. 相似文献
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Suction-induced seepage is pivotal to the installation of caisson foundations in sand. Indeed, the upward pore water flow on the inner side of the caisson wall causes a release of a fraction of soil resistance due to the reduction of the lateral effective stress. A safe caisson installation requires a reliable prediction of soil conditions, especially soil resistance and critical suction for piping. These soil conditions must be predicted for the whole installation process.In this paper, we examine the effect on such prediction of the assumed permeability profile, which is described as a function of depth below the mudline. This study is motivated by the fact that marine sediments generally exhibit a permeability that decreases with depth because of consolidation under gravity. Hence, the question is whether conventional theories based on a constant permeability lead to a conservative prediction of soil conditions or not. Our conclusion is affirmative only regarding piping condition. As for soil resistance, a prediction based on the assumption of a constant permeability is non-conservative. This is due to an overestimated reduction in effective stresses under suction-induced seepage. 相似文献
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最近,由欧盟(则资助的研究项目(Parforce)研究人员发现了海洋藻类与气候变化之间的联系。项目研究人员发现,从海洋藻类及浮游生物释放的碘蒸汽,在海面上浓缩,形成对抗地球变暖的悬浮微粒。此悬浮微粒对地球气候变化及降 相似文献
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目的：研究气阴两虚Lewis肺癌荷瘤模型小鼠的行为学特征、饮水量、摄食量、体质量及肺复方对上述指标及脏器指数的影响。方法：取C57BL/6J小鼠40只,将其随机分为空白组8只、造模组32只。造模组灌服热性中药水煎液合并烟熏制备气阴两虚模型（造模第一阶段,共14 d）,于第15天移植Lewis肺癌细胞（造模第二阶段,共14 d）,按性别、体质量分层随机分为模型组、顺铂组、肺复方组及顺铂+肺复方组（联用组）,连续进行药物干预14 d。以造模每阶段及药物干预第1天的体质量、饮水量和摄食量分别作为基础体质量、基础饮水量和基础摄食量。并于固定时间,每2 d记录动物饮水量和摄食量,每3 d记录动物体质量,药物干预结束后处理动物,测量、计算其去瘤体质量和肝、脾及胸腺的脏器指数。结果：造模第一阶段小鼠饮水量和摄食量减少,造模第二阶段小鼠体质量增加,气阴两虚Lewis肺癌荷瘤模型小鼠脾脏和肝脏指数升高,胸腺指数降低（P<0.05或P<0.01）。药物干预后各组小鼠活动量增加,肺复方组饮水量、体质量增加,顺铂组小鼠摄食量、体质量减少,脾脏指数、去瘤体质量降低,联用组小鼠饮水量增加、摄食量减少,脾脏、胸腺指数升高（P<0.05或P<0.01）。结论：气阴两虚Lewis肺癌荷瘤模型小鼠的饮水量和摄食量减少,体质量增加;肺复方可缓解模型动物口干少饮、形体羸瘦等症状,改善顺铂引起的不良反应,增加模型小鼠脾脏和胸腺指数;肺复方干预肺癌的作用机制可能与其增强机体免疫功能有关。 相似文献
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Le Bas T.P. Somers M.L. Campbell J.M. Beale R. 《Oceanic Engineering, IEEE Journal of》1996,21(4):545-553
For many years, GLORIA has been producing sonar images of the deep ocean floor. In the mid-1980's, the SeaMARC II system came to prominence producing depth values as well as sonar images. The basic method compares the phases of the signals returning from the seafloor to two rows of transducers. The phase differences are converted into angles of arrival and together with the arrival times converted into range and depth values. This capability has now been added to the GLORIA system. The fact that GLORIA uses a 2s FM pulse means the backscattered reverberation can come from a strip of seafloor up to 1.5 km wide. To accommodate this, overlapping complex FFT's are used to produce a time-frequency matrix for the returning signals. In this matrix, a constant range feature appears as a diagonal. Phases are then calculated using a least-mean-squares estimate along diagonals. The main source of error and bias is due to surface reflection, and this is taken into account. The GLORIA swath bathymetry system was tested on two cruises and it was possible to produce depth contours with a good level of confidence. The total swath width was over eight water depths and would have been greater with a more favorable velocity profile. Comparison with other bathymetry data (such as multibeam systems) showed excellent correlation, having a standard deviation of only 4% of total water depth 相似文献
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《Marine Policy》2013
This paper discusses the development of ITQs in Norway. Even if some would deny that anything such exists, fisheries management in Norway has some unmistakable characteristics of an ITQ system. Both boatowners and policy makers have discovered the attractions of transferable quotas, the former as a means to increase their private profits, the latter as a vehicle to reduce fleet overcapacity. The slow evolution of transferability is mainly the result of ideological opposition and opposition to structural changes, the latter involving falling number of fishermen, changes in location of the fishing industry, and changed composition of the fishing fleet. The development of this system in the purse seine fleet and the fleet fishing for cod and similar species is traced. Then the concept of resource rent is discussed, as well as how it has become capitalized in quota values, which show up as a rise in value of long term assets of the fishing industry. 相似文献
20.
The use of Omega sondes, designed for the determination of upper air wind vectors, for relative position measurements on the ground is described. The technique shows promise in measuring the deformation of sea ice, the motion of oceanic surface water, and the trajectories of constant-level balloons. The sondes need not be recollected, are inexpensive, and can be built up to large arrays. The accuracy can be as high as ±30 m within a radius of about 30 km from the observing point. The computation is based on noise suppression of the signal retransmitted from the sondes 相似文献