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1.
肝癌碘油CT分型与临床意义探讨 总被引：2，自引：0，他引：2
本文目的是评价肝癌碘油ＣＴ分型与其与栓塞疗效相应关系,使用的材料和方法是收集和分析我院４５例肝癌肝动脉碘油术后ＣＴ表现,比较分型与栓塞后肿瘤复发情况。结果是碘油在肝癌内的聚集开矿何分三种类型：完全型,斑片型和稀少型。经过随访发现,完全型疗效最佳,全部病例观察１年均未见局部复发：疗效其次是斑片型,其中１６例栓塞后６个月局部复发,余均在８－１０个月内复发;稀少型均在６个月内局部复发。结论是碘油在肝癌形 相似文献
2.
目的：评价支气管动脉灌注化疗栓塞及CT导引下注入无水乙醇与超液化碘油双介入疗法治疗原发性肺癌的疗效，材料和方法：20例原发肺癌进行了单纯支气管动脉化疗，累计68次，20例进行了单纯支气管动脉化疗栓塞，另外40例均进行了双介入治疗，其中20例在支气管动脉化疗栓塞的同时进行了CT导引下注射无水乙醇与超液化碘油混合剂的介入治疗（PEI），化疗栓塞共计28次，局部化疗40次，单纯化疗合并CT介入治疗20例，化疗共64次以上，40例进行的CT导引下注射无水乙醇与超液化碘油混合剂和介入治疗次数累计118次，结果：采用支气管动脉化疗栓塞（或化疗）合并CT导引下注射无水乙醇的双介入疗法治疗有效率分别为90％和80％，单纯支气管动脉化疗栓塞及单纯化疗的临床有效率分别为70％和30％，双介入与单介入的有效率比较有显著性差异（P＜0．01），随访双介入疗法治疗后的患者，3年生存率达到50％，结论：双介入疗法较单纯支气管动脉化疗或化疗栓塞治疗肺癌的临床有效率，生存率明显提高，。 相似文献
3.
目的是探讨乳化碘油增强CT对早期肝癌的诊断作用。方法采用乳化碘油：由碘化油、卵磷脂、甘油等经超声乳化而成：用二乙基亚硝胺诱导法建立大鼠肝癌模型（n＝4）：观察静脉注射乳化碘油（0.4ml／只）后,正常大鼠（n＝4）,及大鼠肝癌病灶的强化情况,并与病理学检查进行对照分析。结果得到：乳化碘油能引起肝脾组织特异性显著强化：透视电镜证实肝细胞参与碘油乳粒的摄取：选取的4只大鼠肝癌模型中,共有14个瘤结,大小4、5±3.4mm;乳化碘油增强CT检出率85.7％（12／14）的瘤结,明显高于平扫时,病灶显示率（14．3％）。结论为乳化碘油是一种潜在的肝脾特异性造影剂,对早期肝癌的检出具有重要价值。 相似文献
4.
支气管动脉灌注化疗栓塞及CT导引下注入无水乙醇治疗肺癌 总被引：1，自引：0，他引：1
目的：分析支气管动脉灌注化序栓塞及CT导引下注入无水乙醇超液化碘油双介入疗法治疗原发性肺癌的疗效。材料和方法：对20例原发肺癌均进行了支气管动脉灌注化疗,累计24次。其中9例在支气管动脉化疗同时进行了栓塞,共13次：单纯化疗11例,共10次。而后20例又分别进行了CT导引下注入无水乙醇的介入治疗,累计49次,其中11例为注入无水乙醇与超液化碘油混合剂,共33例。结果：支气管动脉化疗栓塞及单纯化疗的临床有效率分别为77.77％和45.45％：采用支气管动脉化疗栓塞及CT导引下注射无水乙醇的双介入疗法治疗有效率为88.88％。临床无明显不良反应及并发症。结论：双介入疗法较单独使用其中-种疗法治疗肺癌的临床有效率、生存率明显增高,有显著性差异(P＜0.05)。 相似文献
5.
目的:探讨静脉脑栓塞患者的发病原因、临床表现及CT、磁共振成像(MRI)的影像表现。方法:回顾性分析8例(12处病灶)经临床及影像学联合检查确诊的静脉性脑栓塞患者临床资料。其中6例接受MRI增强扫描,部分患者接受外科手术治疗。分析其治疗前后CT平扫及MRI序列检查结果,评估其影像表现。结果:8例确诊患者中浅表型静脉性栓塞6例(单侧5例、双侧1例),临床表现为头痛、恶心、呕吐、局灶性神经功能缺损或癫痫发作;深部中央型静脉性栓塞者2例(单侧/双侧基底节丘脑静脉梗死各1例),临床表现均较轻且病情进展缓慢,预后效果较理想。12处病灶CT平扫均呈低密度影;T1WI图像呈低信号,DWI图像则呈高信号,T2WI图像呈高信号9处,混杂信号3处;6例行MRI增强扫8处病灶强化环厚薄均匀,但形态欠规则。结论:MRI相较于CT检查,能帮助医师更直观、清晰地了解静脉脑栓塞患者的病灶信息,对针对性治疗方案的拟定和预后效果的准确评估具有积极影响。 相似文献
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目的：探讨CT动脉增强分数（AEF）与肝癌经导管动脉化疗栓塞（TACE）治疗效果的相关性。方法：对我院2019年1月至2020年1月43例原发性肝细胞癌（HCC）患者临床资料进行回顾性分析，所有患者均接受TACE治疗，术前及术后1个月均行CT动态增强扫描检查，根据治疗效果分为治疗有效组及无效组，采用电化学发光法检测各组甲胎蛋白（AFP）水平，比较两组治疗前后AEF、AFP、肿瘤大小变化；采用Pearson系数探究AEF、AFP与肿瘤大小变化的相关性，采用受试者工作特征曲线（ROC）及曲线下面积（AUC）分析肝脏动态增强扫描联合AEF彩图对TACE疗效的评估价值。结果：有效组治疗后AEF、AFP、肿瘤大小均小于治疗前、无效组；Pearson相关性分析结果显示，TACE治疗后AEF、AFP均与肿瘤大小呈正相关；ROC曲线分析结果显示，肝脏动态增强扫描联合AEF评估TACE疗效的AUC为0.902，明显高于肝脏动态增强扫描及AEF单独评估的0.793和0.771。结论：AEF对TACE治疗效果具有良好的评估价值，联合肝脏动态增强扫描能进一步提高准确度，可作为TACE治疗HCC疗效评估的辅助手... 相似文献
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目的：探讨CT与MRI对含脂肪原发性肝癌的诊断及鉴别诊断价值。方法：回顾性分析我院病理证实的22例含脂肪原发性肝癌的CT、MRI表现。结果：22例含脂肪肝癌中,巨块型16例,结节型4例,弥漫型2例。肿瘤单发17例,多发5例;5例多发肿瘤内均只有1个含脂肪病灶,共有含脂肪肿瘤22个。18例肿瘤以实质成分为主,肿瘤内脂肪呈散在、小簇状分布;4例肿瘤以脂肪成分为主,瘤内脂肪呈球状表现,实质成分较少。CT显示肿瘤内斑片状、球状脂肪密度影,MRI脂肪抑制序列及化学位移梯度回波序列正反相位均明确显示脂肪的存在。22例动态增强扫描均较好地显示“快进快出”的影像强化特征,其中15例显示肿瘤假性包膜。结论：CT、MRI能较好显示原发性肝癌的影像特征及肿瘤内所含的脂肪组织,对诊断与鉴别诊断具有重要价值。 相似文献
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作者对３０例原发性肝癌ＬＰ－ＴＡＥ治疗前后有ＣＴ检查的病例进行分析，讨论了碘油选择性沉积在肿瘤内的机理。ＬＰ－ＴＡＥ术后肿瘤区域四种成份的ＣＴ表现，碘油在肿瘤内的三种分布类型及其意义。重点讨论了肝癌ＬＰ－ＴＡＥ术后ＣＴ检查，可以从以下几方面对疗效观察提供帮助，即肿瘤大小变化、碘油聚积量及分布情况、肿瘤区密度变化、子结节的发现和治疗效果、术后并发症的发现等。 相似文献
9.
作者对３０例原发性肝癌ＬＰ－ＴＡＥ治疗前后有ＣＴ检查的病例进行分析，讨论了碘油选择性沉积在肿瘤内的机理．ＬＰ－ＴＡＥ术后肿瘤区域四种成份的ＣＴ表现．碘油在肿瘤内的三种分布类型及其意义。重点讨论了肝癌ＬＰ－ＴＡＥ术后ＣＴ检查，可以从以下几方面对疗效观察提供帮助，即肿瘤大小变化、碘油聚积量及分布情况、肿瘤区密度变化、子结节的发现和治疗效果、术后并发症的发现等． 相似文献
10.
目的:通过分析纤维板层型肝癌的CT/MRI影像学表现,旨在提高对本病的认识,减少误诊率。方法:通过RIS/PACS系统获取病理诊断为纤维板层型肝癌的患者7例,对CT/MRI影像学表现进行描述,并探讨其特异性征象。结果:纤维板层型肝癌影像学表现具有特异性,可以作为诊断与鉴别诊断的依据。CT/MRI表现:一般直径>10cm的单体肿瘤,边界清晰。无肝硬化背景。肿瘤实质成分动脉期混杂强化为主、门静脉期及延迟期强化趋于均匀。肿瘤内部见星状低密度影,增强可能延迟强化。结论:CT/MRI表现具有一定特异性,可以进行诊断与鉴别诊断。 相似文献
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《国际泥沙研究》2019,34(6):564-576
Many parameters are involved in the deposition of a known mass of sand particles discharge from oblique pipes used in a range of engineering applications. Existing knowledge is not sufficient to accurately predict sediment mound dimensions and development from vertical and horizontal pipes. To better understand deposition patterns, laboratory experiments were done to investigate the development of subaqueous sand deposits from oblique pipes in stagnant water. Factors including nozzle diameter, release angle, release height, and sand mass were evaluated. It was found that nozzle size plays the most important role in shape formation and mound development. Release angle and release height were secondarily important. Five different shape patterns were observed and denoted as circular, ellipse, circular-ring, ellipse-ring, and pear-shaped. The scour hole diameter in the middle of the sediment mound was predicted using engineering assumptions and available semi-empirical correlations from the literature. It was found that the existing formulations can accurately predict the size of the scour hole for large release angles (θ = 60°). An aspect ratio of L/do was defined to combine the effect of nozzle size, do, and sand mass where L is the equivalent length of sand particles in a pipe. It was found that the mass balance equation can predict the deposition for L/do < 100. For higher aspect ratios, semi-empirical formulations were developed to predict the deposition length, width, height, and area with ±10% error. 相似文献
13.
Sediment load plays a major role in the morphological evolution of rivers.Therefore,the analysis of the sediment load interaction with hydraulic structures is of main importance in order to enhance the preservation of fish habitats and river morphological characteristics.The present study analyzes the scour mechanisms downstream of a block ramp in live bed conditions,when the sediment supplied by the approaching flow is balanced by the sediment transported out of the scour hole.Experiments were performed in a model flume and the effect of the approaching sediment concentration on the scour geometry was analyzed.It was observed that the scour features depend deeply on the approaching sediment concentration and four main profile configurations were distinguished.The experimental data were analyzed and empirical relationships were developed in order to evaluate the depth and length of a scour hole,the dune height and the distance of the transversal section of maximum dune height from the ramp toe for different hydraulic and geometric conditions.It was also proved that the dynamic equilibrium shape of a scour hole does not depend on the sediment load time history. 相似文献
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In this work a new expression has been developed to predict the settling velocity of a sediment particle which is dispersed in a sediment-fluid mixture during a turbulent flow. A concept of apparent particle diameter has been introduced and is defined by the diameter of the spherical volume in which the particle can move randomly after collision with other particles in suspension. The effect of suspension concentration is studied on the mass density of the sediment-fluid mixture. It has been shown that the settling velocity of sediment particle in a sediment-fluid mixture is a function of different characteristics of the sediment particle such as settling velocity in clear fluid, suspension concentration, relative mass density and Reynolds number. The model has shown good agreement when compared with previously published experimental data and it’s prediction accuracy is superior than the other existing models. 相似文献
15.
Rare earth elements (REEs) have been successfully used as a sediment tracer, but the REE technique has never been used for studying sediment sources for a multi‐year period. A nearly four‐year field experiment was conducted on a small agricultural watershed near Coshocton, OH, USA, to assess the applicability of the REE technique for a multi‐year period and to evaluate the relative contributions of sediment sources in the watershed. Tracer depletion and tracer enrichment ratio (ratio of the tracer concentrations in sediment to the concentrations in the soil in the areas of application) were evaluated to examine the applicability and accuracy of the technique. A minimum of 91 per cent of the mass of the applied elements was still available on any individual morphological element at the end of the experimental period. The tracer enrichment ratio varied from 0·4 to 2·3, and it was not significantly related to time. The relative contributions of six morphological elements within the watershed were evaluated as proportions to total sediment yield. The relative contribution of the lower channel was significantly increased as a function of the amount of sediment yield, while that of the lower backslope was significantly decreased. The relative contribution of the lower channel significantly decreased as a function of cumulative sediment yield, while the contributions of the shoulder and the upper backslope significantly increased. Our results showed that the REE technique can be used to track sediment sources for a relatively long period with two limitations or potential sources of error associated with a selective depletion of tracers and a contamination of downslope areas with tagged sediments from upslope areas. Copyright © 2006 John Wiley & Sons, Ltd. 相似文献
16.
In this paper, a systematic investigation into the effect of both the type of impervious members and the reservoir bottom sediment on the dynamic response of embankment dams has been carried out using the finite and infinite element coupled method. It has been demonstrated from the numerical results that: (1) the resonant frequencies of an embankment dam—foundation system with an upstream inclined concrete apron are different from those with a central clay core; (2) the type of impervious members has a significant influence on the amplification factors of the system in the low frequency range of excitation, but has little effect in the high frequency range of excitation; (3) the foundation material of an embankment dam affects the dynamic response of the dam drastically; (4) the inclusion of the reservoir bottom sediment has a considerable effect on amplification factors of embankment dams in the case of P-wave incidences, but has little influence in the case of SV-wave vertical incidences; and (5) the reservoir bottom sediment also has a profound effect on the deformed shape of the embankment dam for both P-wave and SV-wave incidences. 相似文献
17.
The 184 m cargo ship Bunga Teratai Satu collided with Sudbury Reef, part of the Great Barrier Reef and remained grounded for 12 days. The ship was re-floated only 3 days prior to the November 2000 mass coral spawning. No cargo or fuel was lost but the impact resulted in significant contamination of the reef with anti-foulant paint containing tributyltin (TBT), copper (Cu) and zinc (Zn). Larvae of the reef-building scleractinian coral Acropora microphthalma were exposed to various concentrations of sediment collected from the grounding site in replicated laboratory experiments. Two experiments were performed, both of which used varying ratios of contaminated and control site sediment in seawater as treatments. In the first experiment, the influence of contaminated sediment on larval competency was examined using metamorphosis bioassays. In the second, the effect of contaminated sediment upon larval recruitment on pre-conditioned terracotta tiles was assessed. In both experiments, sediment containing 8.0 mg kg(-1) TBT, 72 mg kg(-1) Cu and 92 mg kg(-1) Zn significantly inhibited larval settlement and metamorphosis. At this level of contamination larvae survived but contracted to a spherical shape and swimming and searching behaviour ceased. At higher contamination levels, 100% mortality was recorded. These results indicate that the contamination of sediment by anti-fouling paint at Sudbury Reef has the potential to significantly reduce coral recruitment in the immediate vicinity of the site and that this contamination may threaten the recovery of the resident coral community unless the paint is removed. 相似文献
18.
Roychoudhury AN 《Marine pollution bulletin》2006,52(4):397-403
Sediment extraction methods to quantify metal concentration in aquatic sediments usually present limitations in accuracy and reproducibility because metal concentration in the supernatant is controlled to a large extent by the physico-chemical properties of the sediment that result in a complex interplay between the solid and the solution phase. It is suggested here that standardization of sediment extraction methods using pure mineral phases or reference material is futile and instead the extraction processes should be calibrated using site-specific sediments before their application. For calibration, time dependent release of metals should be observed for each leachate to ascertain the appropriate time for a given extraction step. Although such an approach is tedious and time consuming, using iron extraction as an example, it is shown here that apart from quantitative data such an approach provides additional information on factors that play an intricate role in metal dynamics in the environment. Single step ascorbate, HCl, oxalate and dithionite extractions were used for targeting specific iron phases from saltmarsh sediments and their response was observed over time in order to calibrate the extraction times for each extractant later to be used in a sequential extraction. For surficial sediments, an extraction time of 24 h, 1 h, 2 h and 3 h was ascertained for ascorbate, HCl, oxalate and dithionite extractions, respectively. Fluctuations in iron concentration in the supernatant over time were ubiquitous. The adsorption-desorption behavior is possibly controlled by the sediment organic matter, formation or consumption of active exchange sites during extraction and the crystallinity of iron mineral phase present in the sediments. 相似文献
19.
目的:研究肩峰下撞击综合征与MSCT下肩峰分型的关系。方法:对2013年1月至2015年1月在我院确诊为肩峰下撞击综合征的110例患者行MSCT扫描,将所有患者按照不同年龄阶段、性别、肩峰的不同位置进行分组,比较不同肩峰形态在不同年龄组、不同性别组以及不同位置组的分布情况。结果:Ⅰ型、Ⅱ型肩峰随年龄增长,比例逐渐降低,Ⅲ型肩峰随年龄增长,比例逐渐增大。Ⅱ型肩峰A组患者比例为51.6%,较B组和C组明显高,Ⅲ型肩峰A组患者比例为22.6%,较B组和C组明显低(P<0.05)。男性组与女性组Ⅰ型、Ⅱ、Ⅲ型肩峰形态所占比例比较,差异均不具有统计学意义(P>0.05)。Ⅲ型肩峰形态右肩较多,所占比例为52.5%,明显高于左肩组(P<0.05)。结论:MSCT可以清楚显示肩峰的形态与结构,肩峰下撞击综合征患者弯曲型肩峰随年龄增大比例逐渐减少,钩型肩峰多在右肩,且随年龄增大比例逐渐增大。 相似文献