Protective effects of Ecklonia cava extract on the toxicity and oxidative stress induced by hair dye in in-vitro and in-vivo models     

Oh  Jae-Young  Ryu  Bo-Mi  Yang  Hye-Won  Kim  Eun-A.  Lee  Jung-Suck  Jeon  You-Jin 《中国海洋湖沼学报》2019,37(3):909-917

Oxidative hair dyes containing p-phenylenediamine(PPD) are reported to induce an allergic reaction by promoting oxidative stress when absorbed through the skin. Despite the associated risk, these hair dyes remain popular owing to their convenience and sharpness of color. This makes it important to minimize the cytotoxicity and oxidative stress induced by PPD-containing hair dyes. Ecklonia cava extract has been evaluated in different studies for its protective effects against external stress in fibroblasts and keratinocytes. Our study was aimed at using in-vitro and in-vivo models to investigate the extract's effects on cytotoxicity of and oxidative stress induced by PPD-containing hair dyes. Analysis of CIEL*a*b* Color space was first used to determine the range of E. cava extract that would not interfere with the coloring ability of the dye upon addition. Subsequently, the set ranges of E. cava extract(5% and 7%) were added to the hair dye and their toxicity assessed by evaluating the viability of fibroblasts and keratinocytes. The effects on developmental phenotypes and induction of oxidative stress by hair dye were evaluated and compared with those of hair dyes containing different contents of E. cava extract using an in-vivo zebrafish model. Our results showed that E. cava extract in hair dye could significantly decrease the cytotoxicity and levels of oxidative stress caused by hair dyes containing PPD in both in-vitro and in-vivo models.These results suggest that the addition of 7% E. cava extract to 250 μg/mL hair dye does not interfere with the coloring ability of the dye while showing significant protective effects against the hair dye. The study proposes that the use of E. cava extract as an adduct to hair dyes containing PPD reduces the cytotoxicity and oxidative stress induced by these hair dyes.  相似文献   

Spatial variations of small phytoplankton contributions in the Northern Bering Sea and the Southern Chukchi Sea     

Sang Heon Lee  Jongseong Ryu  Dabin Lee  Jung-Woo Park  Jae-Il Kwon  Jingping Zhao 《地理信息系统科学与遥感》2019,56(5):794-810

Phytoplankton size classes (hereafter, PSCs) were derived from satellite ocean color data using a present phytoplankton abundance-based optical algorithm in the northern Bering and southern Chukchi Seas to characterize the spatial and seasonal variations of the different PSC and investigate the contributions of small phytoplankton to the total phytoplankton biomass. The comparison results showed that the phytoplankton abundance-based method approach could reasonably classify the three PSCs (pico-, nano-, and micro phytoplankton). The satellite maps of the dominant PSCs were derived using long-term satellite ocean color data. The general spatial distribution showed that the large (micro-) phytoplankton were dominant in the coastal waters and the west side of the Bering strait, while the small size (nano- or pico-) phytoplankton were dominant in the open ocean waters. Nano- and microphytoplankton were dominant in May and October in most of the study area, while pico-phytoplankton were dominant in the summer months in the open ocean waters. The annual variation in small phytoplankton dominance had a strong positive relationship with the annual mean sea surface temperature (SST), which is consistent with the increasing dominance of small phytoplankton biomass as water temperature increases. Microphytoplankton have an apparent increasing trend in the southeastern Chukchi Sea but slightly decreasing trends in Chirikov and St. Lawrence Island Polynya (SLIP). In contrast, there were increasing trends in picophytoplankton in Chirikov and SLIP, which seems to be related to increasing annual SST. It is crucial to monitor changes in dominant groups of phytoplankton community in the Bering and Chukchi Seas as important biological hotspots responding to the recent changes in environmental conditions.  相似文献   

Gas hydrates in the western deep-water Ulleung Basin, East Sea of Korea   总被引：1，自引：0，他引：1  

Byong-Jae Ryu  Michael Riedel  Ji-Hoon Kim  Roy D. Hyndman  Young-Joo Lee  Bu-Heung Chung  Il-Soo Kim 《Marine and Petroleum Geology》2009,26(8):1483-1498

Geophysical surveys and geological studies of gas hydrates in the western deep-water Ulleung Basin of the East Sea off the east coast of Korea have been carried out by the Korea Institute of Geoscience and Mineral Resources (KIGAM) since 2000. The work included a grid of 4782 km of 2D multi-channel seismic reflection lines and 11 piston cores 5–8 m long. In the piston cores, cracks generally parallel to bedding suggest significant in-situ gas. The cores showed high amounts of total organic carbon (TOC), and from the southern study area showed high residual hydrocarbon gas concentrations. The lack of higher hydrocarbons and the carbon isotope ratios indicate that the methane is primarily biogenic. The seismic data show areas of bottom-simulating reflectors (BSRs) that are associated with gas hydrates and underlying free gas. An important observation is the numerous seismic blanking zones up to 2 km across that probably reflect widespread fluid and gas venting and that are inferred to contain substantial gas hydrate. Some of the important results are: (1) BSRs are widespread, although most have low amplitudes; (2) increased P-wave velocities above some BSRs suggest distributed low to moderate concentration gas hydrate whereas a velocity decrease below the BSR suggests free gas; (3) the blanking zones are often associated with upbowing of sedimentary bedding reflectors in time sections that has been interpreted at least in part due to velocity pull-up produced by high-velocity gas hydrate. High gas hydrate concentrations are also inferred in several examples where high interval velocities are resolved within the blanking zones. Recently, gas hydrate recoveries by the piston coring and deep-drilling in 2007 support the interpretation of substantial gas hydrate in many of these structures.  相似文献   

Physiological and biochemical responses of <Emphasis Type="Italic">Prorocentrum minimum</Emphasis> to high light stress     

So Yun Park  Eun Seok Choi  Jinik Hwang  Donggiun Kim  Tae Kwon Ryu  Taek-Kyun Lee 《Ocean Science Journal》2009,44(4):199-204

Prorocentrum minimum is a common bloomforming photosynthetic dinoflagellate found along the southern coast of Korea. To investigate the adaptive responses of P. minimum to high light stress, we measured growth rate, and generation of reactive oxidative species (ROS), superoxide dismutase (SOD), catalase (CAT), and malondialdehyde (MDA) in cultures exposed to normal (NL) and high light levels (HL). The results showed that HL (800 μmol m^?2 s^?1) inhibited growth of P. minimum, with maximal inhibition after 7–9 days. HL also increased the amount of ROS and MDA, suggesting that HL stress leads to oxidative damage and lipid peroxidation in this species. Under HL, we first detected superoxide on day 4 and H₂O₂ on day 5. We also detected SOD activity on day 5 and CAT activity on day 6. The level of lipid peroxidation, an indicator of cell death, was high on day 8. Addition of diphenyleneiodonium (DPI), an NAD(P)H inhibitor, decreased the levels of superoxide generation and lipid peroxidation. Our results indicate that the production of ROS which results from HL stress in P. minimum also induces antioxidative enzymes that counteract oxidative damage and allow P. minimum to survive.  相似文献   

Late Holocene distal mud deposits off the Nakdong delta,SE Korea: evidence for shore-parallel sediment transport in a current-dominated setting     

Jong-Hwa Chun  Yuri Kim  Jang-Jun Bahk  Young Jun Kim  Dong-Hyo Kang  Yong Hoon Kim  Gil Young Kim  Byong-Jae Ryu 《Geo-Marine Letters》2015,35(6):475-485

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Computational Fluid Dynamics Modelling of the Diurnal Variation of Flow in a Street Canyon     

Kyung-Hwan Kwak  Jong-Jin Baik  Sang-Hyun Lee  Young-Hee Ryu 《Boundary-Layer Meteorology》2011,141(1):77-92

Urban surface and radiation processes are incorporated into a computational fluid dynamics (CFD) model to investigate the diurnal variation of flow in a street canyon with an aspect ratio of 1. The developed CFD model predicts surface and substrate temperatures of the roof, walls, and road. One-day simulations are performed with various ambient wind speeds of 2, 3, 4, 5, and 6 ms⁻¹, with the ambient wind perpendicular to the north–south oriented canyon. During the day, the largest maximum surface temperature for all surfaces is found at the road surface for an ambient wind speed of 3 ms⁻¹ (56.0°C). Two flow regimes are identified by the vortex configuration in the street canyon. Flow regime I is characterized by a primary vortex. Flow regime II is characterized by two counter-rotating vortices, which appears in the presence of strong downwind building-wall heating. Air temperature is relatively low near the downwind building wall in flow regime I and inside the upper vortex in flow regime II. In flow regime II, the upper vortex expands with increasing ambient wind speed, thus enlarging the extent of cool air within the canyon. The canyon wind speed in flow regime II is proportional to the ambient wind speed, but that in flow regime I is not. For weak ambient winds, the dependency of surface sensible heat flux on the ambient wind speed is found to play an essential role in determining the relationship between canyon wind speed and ambient wind speed.  相似文献   

Stability Assessment of a Pit Slope Under Blast Loading: A Case Study of Pasir Coal Mine     

D. Deb  K. N. R. Kaushik  B. H. Choi  C. H. Ryu  Y. B. Jung  C. Sunwoo 《Geotechnical and Geological Engineering》2011,29(4):419-429

In Pasir mine, coal seams and host rocks of varying thickness have been uniquely deposited with an average dip angle of 85°. The host rocks are weak and mainly composed of mudstone and sandstone comprising of 90–95% of the total pit volume. The thickness of coal seams and host rocks ranges from sub-metric to few tenths of meter. The overall safe pit slope angle was evaluated to be 27° for mining depth of 50–150 m. Several slopes failure incidents have occurred in the mine causing considerable disruption in production and monetary loss. It is envisaged that slope failures may be triggered due to blasting conducted in steeply dipping stratified deposit. In order to investigate the causes of slope failures, peak particle velocity (PPV) and accelerations at various locations from the blast site have been measured. In addition, finite element models of pit slope have been analyzed by applying static or gravity loading as well as blasting or dynamic loading. This paper elaborates the results of in situ measurements of ground vibration and numerical investigation and suggests possible causes of slope failures in Pasir mine.  相似文献   

Sediment mounds and other sedimentary features related to hydrate occurrences in a columnar seismic blanking zone of the Ulleung Basin, East Sea, Korea     

Jong-Hwa Chun  Byong-Jae Ryu  Byeong-Kook Son  Ji-Hoon Kim  Joo Yong Lee  Jang-Jun Bahk  Hag-Ju Kim  Kyung Sik Woo  Odette Nehza 《Marine and Petroleum Geology》2011,28(10):1787-1800

A mound related to a cold vent in a columnar seismic blanking zone (CSBZ) was formed around site UBGH1-10 in the central Ulleung Basin (2077 m water depth), East Sea, Korea. The mound is 300–400 m wide and 2–3 m high according to multi-beam bathymetry, 2–7 kHz sub-bottom profiler data, and multi-channel reflection seismic data. Seafloor topography and characteristics were investigated using a remotely operated vehicle (ROV) around site UBGH1-10, which is located near the northern part of the mound. The origin of the mound was investigated through lithology, mineralogy, hydrate occurrence, and sedimentary features using dive cores, piston cores, and a deep-drilling core. The CSBZ extends to ∼265 ms two-way traveltime (TWT) below the seafloor within a mass-transport deposit (MTD) unit. Gas hydrate was entirely contained 6–141 m below the seafloor (mbsf) within hemipelagic deposits intercalated with a fine-grained turbidite (HTD) unit, characteristically associated with high resistivity values at site UBGH1-10. The hydrate is commonly characterized by veins, nodules, and massive types, and is found within muddy sediments as a fracture-filling type. Methane has been produced by microbial reduction of CO₂, as indicated by C₁/C₂₊, δ¹³CCH4, and δD₄CH analyses. The bowl-shaped hydrate cap revealed at 20–45 ms TWT below the seafloor has very high resistivity and high salinity, suggesting rapid and recent gas hydrate formation. The origin of the sediment mound is interpreted as a topographic high formed by the expansion associated with the formation of the gas hydrate cap above the CSBZ. The lower sedimentation rate of the mound sediments may be due to local enhancement of bottom currents by topographic effects. In addition, no evidence of gas bubbles, chemosynthetic communities, or bacterial mats was observed in the mound, suggesting an inactive cold vent.  相似文献   

Spatial polychaeta habitat potential mapping using probabilistic models     

Jong-Kuk Choi  Hyun-Joo Oh  Bon Joo Koo  Joo-Hyung Ryu  Saro Lee 《Estuarine, Coastal and Shelf Science》2011

The purpose of this study was to apply probabilistic models to the mapping of the potential polychaeta habitat area in the Hwangdo tidal flat, Korea. Remote sensing techniques were used to construct spatial datasets of ecological environments and field observations were carried out to determine the distribution of macrobenthos. Habitat potential mapping was achieved for two polychaeta species, Prionospio japonica and Prionospio pulchra, and eight control factors relating to the tidal macrobenthos distribution were selected. These included the intertidal digital elevation model (DEM), slope, aspect, tidal exposure duration, distance from tidal channels, tidal channel density, spectral reflectance of the near infrared (NIR) bands and surface sedimentary facies from satellite imagery. The spatial relationships between the polychaeta species and each control factor were calculated using a frequency ratio and weights-of-evidence combined with geographic information system (GIS) data. The species were randomly divided into a training set (70%) to analyze habitat potential using frequency ratio and weights-of-evidence, and a test set (30%) to verify the predicted habitat potential map. The relationships were overlaid to produce a habitat potential map with a polychaeta habitat potential (PHP) index value. These maps were verified by comparing them to surveyed habitat locations such as the verification data set. For the verification results, the frequency ratio model showed prediction accuracies of 77.71% and 74.87% for P. japonica and P. pulchra, respectively, while those for the weights-of-evidence model were 64.05% and 62.95%. Thus, the frequency ratio model provided a more accurate prediction than the weights-of-evidence model. Our data demonstrate that the frequency ratio and weights-of-evidence models based upon GIS analysis are effective for generating habitat potential maps of polychaeta species in a tidal flat. The results of this study can be applied towards conservation and management initiatives for the macrofauna of tidal flats.  相似文献   

Characterizing Excavation Damaged Zone and Stability of Pressurized Lined Rock Caverns for Underground Compressed Air Energy Storage   总被引：2，自引：2，他引：0  

Hyung-Mok Kim  Jonny Rutqvist  Ju-Hwan Jeong  Byung-Hee Choi  Dong-Woo Ryu  Won-Kyong Song 《Rock Mechanics and Rock Engineering》2013,46(5):1113-1124

In this paper, we investigate the influence of the excavation damaged zone (EDZ) on the geomechanical performance of compressed air energy storage (CAES) in lined rock caverns. We conducted a detailed characterization of the EDZ in rock caverns that have been excavated for a Korean pilot test program on CAES in (concrete) lined rock caverns at shallow depth. The EDZ was characterized by measurements of P- and S-wave velocities and permeability across the EDZ and into undisturbed host rock. Moreover, we constructed an in situ concrete lining model and conducted permeability measurements in boreholes penetrating the concrete, through the EDZ and into the undisturbed host rock. Using the site-specific conditions and the results of the EDZ characterization, we carried out a model simulation to investigate the influence of the EDZ on the CAES performance, in particular related to geomechanical responses and stability. We used a modeling approach including coupled thermodynamic multiphase flow and geomechanics, which was proven to be useful in previous generic CAES studies. Our modeling results showed that the potential for inducing tensile fractures and air leakage through the concrete lining could be substantially reduced if the EDZ around the cavern could be minimized. Moreover, the results showed that the most favorable design for reducing the potential for tensile failure in the lining would be a relatively compliant concrete lining with a tight inner seal, and a relatively stiff (uncompliant) host rock with a minimized EDZ. Because EDZ compliance depends on its compressibility (or modulus) and thickness, care should be taken during drill and blast operations to minimize the damage to the cavern walls.  相似文献