CYP1B1 knockdown does not alter synergistic developmental toxicity of polycyclic aromatic hydrocarbons in zebrafish (Danio rerio)     

Timme-Laragy AR  Noyes PD  Buhler DR  Di Giulio RT 《Marine environmental research》2008,66(1):85-87

Polycyclic aromatic hydrocarbons (PAHs) are contaminants increasing in the environment largely due to burning of fossil fuels. Our previous work identified a synergistic toxicity interaction in zebrafish embryos occurring when PAHs that are agonists for the aryl hydrocarbon receptor (AHR) co-occur with PAHs that are CYP1A inhibitors. This toxicity is mediated by the AHR2, and morpholino knockdown of CYP1A exacerbated toxicity. This study tested two hypotheses: (1) in the absence of functional CYP1A, metabolism of PAHs is shunted towards CYP1B1, which has been shown in mammals to produce more reactive metabolites of PAHs; alternatively, (2) CYP1B1 serves a protective role similar to CYP1A. We used a morpholino approach to knockdown CYP1B1 alone and in co-knockdown with CYP1A to determine whether we could alter deformities caused by synergistic toxicity of PAHs. CYP1B1 knockdown was not different from non-injected controls; nor were CYP1B1+CYP1A co-knockdown deformities different from CYP1A knockdown alone. These data suggest that CYP1B1 is not a significant factor in causing synergistic toxicity of PAHs, nor, in contrast to CYP1A, in providing protection.  相似文献   

Anomalous Emissions of SO2 During the Recent Eruption of Santa Ana Volcano, El Salvador, Central America   总被引：1，自引：0，他引：1  

Rodolfo Olmos  José Barrancos  Claudia Rivera  Francisco Barahona  Dina L. López  Benancio Henriquez  Agustín Hernández  Efrain Benitez  Pedro A. Hernández  Nemesio M. Pérez  Bo Galle 《Pure and Applied Geophysics》2007,164(12):2489-2506

Santa Ana volcano in western El Salvador, Central America, had a phreatic eruption at 8:05 am (local time) on October 1, 2005, 101 years after its last eruption. However, during the last one hundred years this volcano has presented periods of quiet degassing with fumarolic activity and an acidic lake within its crater. This paper presents results of frequent measurements of SO₂ degassing using the MiniDOAS (Differential Optical Absorption Spectroscopy) system and a comparison with the volcanic seismicity prior to the eruption, during, and after the eruption. Vehicle measurements of SO₂ flux were taken every hour during the first nine days of the eruption and daily after that. The period of time reported here is from August to December, 2005. Three periods of degassing are distinguished: pre-eruptive, eruptive, and post-eruptive periods. The intense activity at Santa Ana volcano started in July 2005. During the pre-eruptive period up to 4306 and 5154 ton/day of SO₂ flux were recorded on October 24 and September 9, 2005, respectively. These values were of the same order of magnitude as the recorded values just after the October 1^st eruption (2925 ton/day at 10:01 am). Hourly measurements of SO₂ flux taken during the first nine days after the main eruptive event indicate that explosions are preceded by an increase in SO₂ flux and that this parameter reaches a peak after the explosion took place. This behavior suggests that increasing accumulation of exsolved magmatic gases occurs within the magmatic chamber before the explosions, increasing the pressure until the point of explosion. A correlation between SO₂ fluxes and RSAM (Real Time Seismic Amplitude Measurements) is observed during the complete sampling period. Periodic fluctuations in the SO₂ and RSAM values during the entire study period are observed. One possible mechanism explaining these fluctuations it that convective circulation within the magmatic chamber can bring fresh magma periodically to shallow levels, allowing increasing degasification and then decreasing degasification as the batch of magma lowers its gas content, becomes denser, and sinks to give space to a new magma pulse. These results illustrate that the measurements of SO₂ flux can provide important warning signals for incoming explosive activity in active volcanoes.  相似文献   

Influence of land runoff on rates and agents of bioerosion of coral substrates     

Hutchings P  Peyrot-Clausade M  Osnorno A 《Marine pollution bulletin》2005,51(1-4):438-447

Annually large volumes of fresh water laden with sediment are washed down the Daintree River in North Queensland into the Great Barrier Reef lagoon. To investigate the effects of land runoff on bioerosion, samples of recently killed colonies of Porites were laid at 6 sites on a cross shelf transect from Snapper Island at the entrance to the river to Osprey Reef, approximately 328 km from the river mouth out in the Coral Sea. Rates and agents of bioerosion were determined over 4 years and inshore sites exhibited significantly lower rates of total bioerosion than the other sites. Offshore sites experienced high rates of bioerosion primarily due to grazing and internal bioerosion by macroborers such as sponges and bivalves was also important at some of these sites. Inshore sites were covered in heavy layers of silt which inhibited colonization and growth of microborers, primarily algae. This resulted in lower levels of grazing than at offshore sites. However the activity of macroborers (primarily sponges and bivalves) was often high at these sites. The macroboring communities differed between sites and over time and it is hypothesised that these site differences were due to different levels of terrestrial runoff. These results are compared with those from French Polynesia where contaminated terrestrial runoff greatly influenced rates and agents of bioerosion. However other factors such as overfishing may also play an important role in some locations.  相似文献   

Metal speciation and environmental impact on sandy beaches due to El Salvador copper mine, Chile   总被引：1，自引：0，他引：1  

Ramirez M  Massolo S  Frache R  Correa JA 《Marine pollution bulletin》2005,50(1):62-72

Several coastal rocky shores in northern Chile have been affected by the discharges of copper mine tailings. The present study aims to analyze the chemical speciation of heavy metals in relation to the diversity of sessile species in the rocky intertidal benthic community on the northern Chilean coast, which is influenced by the presence of copper mine tailings. In particular, the chemical forms of Cd, Cu, Fe, Mn, Ni, Pb and Zn in beach sediment samples collected in the area influenced by El Salvador mine tailings were studied using a sequential chemical extraction method. In general, all the elements present a maximum concentration in the area near the actual discharge point (Caleta Palito). With regard to Cu and Mn, the concentrations range between 7.2-985 and 746-22,739 microg/g respectively, being lower than background levels only in the control site of Caleta Zenteno. Moreover, the correlation coefficients highlight that Fe, Mn and Ni correlate significantly and positively in the studied area, showing a possible common, natural origin, whilst Cu shows a negative correlation with Fe, Mn and Ni. It could be possible that Cu has an anthropogenic origin, coming from mining activity in the area. Cd, Fe, Mn, Ni, Pb and Zn are mostly associated with the residual phase, whilst Cu presents a different speciation pattern, as resulted from selective extractions. In fact, Cu is highly associated with organic and exchangeable phases in contaminated localities, whilst it is mainly bound to the residual phase in control sites. Moreover, our results, compared to local biological diversity, showed that those sites characterized by the highest metal concentrations in bioavailable phase had the lowest biodiversity.  相似文献   

Effects of soil resistivity on currents induced on pipelines     

Ana Osella  Alicia Favetto 《Journal of Applied Geophysics》2000,44(4):45

The goal of cathodic protection is to prevent corrosion by maintaining buried pipelines at a constant potential with respect to the surrounding soil. In practice, however, the implementation is very complicated since many factors can contribute to the current flowing off the pipe. Design requires characterization of the parameters impacting the corrosion process, such as soil resistivity, size of the pipe and quality of the coating.In the present paper, we have studied the effect of geomagnetic fields on the pipe-induced currents considering it as an additional cause of corrosion. A theoretical method implemented to model the induced currents was tested in a previous work and the effect during disturbed days was quantified. This theoretical model indicated that the intensity of the current induced in a pipeline by the varying geomagnetic field depends on the intensity and rate of change of the field and the electrical resistivity of the soil. This induced current is in equilibrium with the host current and there is no current drainage between the pipeline and the host until, along the length of the pipeline, the host resistivity becomes different. At that point, current must flow between the pipe and host in order to establish a new equilibrium. It is this drainage current, flowing between the pipeline and the host, which causes corrosion problems.Following these results, experimental tests were performed in Tierra del Fuego. In this zone, a geophysical study was made to determine the discontinuities in soil resistivities and simultaneous measurements of the geomagnetic field and the drainage of current were recorded at different sites. The results obtained from the correlation of the data are consistent with the theoretical predictions.  相似文献   

Effect of temperature and illumination on pyrite oxidation between pH 2 and 6     

Martin Schoonen  Alicia Elsetinow  Michael Borda  Daniel Strongin 《Geochemical transactions》2000,1(1):23-11

The effect of heat and illumination with visible light on the oxidation of pyrite with dissolved molecular oxygen in solutions between pH 2 and 6 has been investigated using a combination of surface science experiments and batch oxidation experiments. The rate of the oxidation of pyrite is strongly dependent on temperature. It is, however, not possible to cast the temperature dependence in a simple Arrhenius equation because the magnitude of the activation energy depends on the progress variable chosen. Activation energies based on proton release rate, sulfate release rate, and total iron release rate vary by as much as 40 kJ mol^-1, suggesting that the oxidation mechanism of the sulfur and iron component of pyrite are largely independent of each other. This difference in mechanism can also explain why the reaction rates on the basis of these three different progress variables do not show the same pH dependence. Exposed to visible light, the rate of pyrite oxidation is under most conditions accelerated by less than a factor of two. Some of this acceleration may be accounted for by a light-induced heating of the pyrite surface. Surface science experiments employing photoelectron spectroscopy show no evidence for significant changes in the chemical composition of the surface as a function of exposure to visible light. The batch sorption experiments show, however, that the reaction stoichiometry changes somewhat, which indicates that there might be a change in reaction mechanism as a result of exposure to visible light.  相似文献   

Effect of sub-indicator weighting schemes on the spatial dependence of multidimensional phenomena     

Libório  Matheus Pereira  de Abreu  João Francisco  Ekel  Petr Iakovlevitch  Machado  Alexei Manso Correa 《Journal of Geographical Systems》2023,25(2):185-211

Journal of Geographical Systems - The weighting of sub-indicators is widely debated in the composite indicator literature. However, these weighting schemes’ effects on the composite...  相似文献   

Mixed layer depth (MLD) variability in the southern Bay of Biscay. Deepening of winter MLDs concurrent with generalized upper water warming trends?     

Raquel Somavilla Cabrillo  Cesar González-Pola  Manuel Ruiz-Villarreal  Alicia Lavín Montero 《Ocean Dynamics》2011,61(9):1215-1235

Mixed layer depth (MLD) variability from seasonal to decadal time scales in the Bay of Biscay is studied in this work. A hydrographic time series running since 1991 in the study area, a climatology of the upper layer vertical structure based on the topology of this temperature profile time series and a one-dimensional water column model have been used for this purpose. The prevailing factors driving MLD variability have been determined with detail, and agreement with observations is achieved. Tests carried out to investigate climatological profile skill to reproduce the upper layer temporal evolution have demonstrated its ability to simulate variability at seasonal time scales and reproduce the most conspicuous events observed. This has enabled us to carry out a reconstruction of the MLD variability for the last 60 years in the study area. Favourable sequence of intense mixing events explains interannual differences and cases of extraordinary deepening of winter mixed layer. The negative phase of the Eastern Atlantic pattern seems to determine important interannual variability through intense episodes of cooling and mixing as in winter 2005 in the Bay of Biscay. Low-frequency variability is also observed. A very striking and unexpected shallower winter MLD during the 1970s and 1980s than those observed from 1995 has been found. Simulation results support this counter-intuitive outcome of shallower winter mixed layers concurrent with generalized upper water warming trends reported on several occasions for the area. The long-term trends in MLD seem related with decadal variability in the North Atlantic Oscillation, being in phase and opposition with other deepening-shallowing cycles found from subtropical-to-subpolar areas in the North Atlantic.  相似文献   

Contrasting perspectives on mangroves in arid Northwestern Mexico: Implications for integrated coastal management     

Xavier López-Medellín  Alicia CastilloExequiel Ezcurra 《Ocean & Coastal Management》2011,54(4):318-329

Mangroves in Northwestern Mexico are vital to maintain coastal environments healthy, to provide nutrients for several food chains, and to supply valuable goods and services that sustain and improve human livelihoods. Many of these values offer a range of opportunities for economic development that attract workers, investors and developers. Recently, federal privatization policies have promoted an accelerated coastal development of this region to obtain large profits in short times, creating competing and overlapping interests to use coastal environments and control key resources. Such intense developments are modifying the ecological conditions of many coastal areas, threatening the provision of important ecosystem services to society. After years of centralized decisions, new paradigms are needed to achieve a coastal management that ensures long-term ecosystem maintenance, fair resource use and social equity. Recognizing the multiplicity of actors involved in coastal management and using a qualitative research methodology, we identified and explored the perspectives of different key stakeholders in the states of Baja California Sur and Sonora, Mexico, to better understand their views on mangroves use and management as well as the interaction among them. We discuss similarities and/or discrepancies found among stakeholders’ perceptions by describing their central ideas and identifying overlapping interests that may create conflicts when defining development and conservation programs or formulating policies. This information also intends to encourage further research on the social-ecological system of the coasts in Northwestern Mexico and to contribute to address coastal management issues in integrated ways that consider the social dimension through documenting stakeholders’ narratives in the future.  相似文献   

A transition from a decelerated to an accelerated phase of the universe expansion from the simplest non-trivial polynomial function of T in the f(R,T) formalism     

P. H. R. S. Moraes  G. Ribeiro  R. A. C. Correa 《Astrophysics and Space Science》2016,361(7):227

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