Protective effect of topically applied polypeptide from Chlamys farreri against ultraviolet radiation-induced chronic skin damage in guinea pig     

Chi Mingliang  Cao Pengli  Yu Guoying  Zhu Li  Wang Yuejun  Wang Chunbo 《中国海洋湖沼学报》2003,21(4):319-323

Polypeptide fromChlamys farreri (PCF), a topical polypeptide isolated fromChlamys farreri, was used in this experiment aimed to investigate the photoprotective effect of PCF against chronic skin damage induced by ultraviolet A (UVA) and ultraviolet B (UVB) radiation. The chronic ultraviolet-irradiated guinea pig model was established, and visible changes in the skin including wrinkling, sagging and erythema were observed. Malondialdehyde (MDA) and antioxidant enzymes including superoxide dismutase (SOD) and glutathione peroxidase (GSH-px) in the dorsal skin were determined using biochemical methods. The results showed: (1) PCF (5 % and 20%) could greatly protect the dorsal skin of guinea pig against wrinkling, sagging and erythema induced by UV radiation in a concentration-dependent manner. (2) PCF could reduce MDA formation in the dorsal skin caused by UV irradiation, while increasing the activities of SOD and GSH-px. (3) The differences among the PCF groups and UV model group were significant (P<0.05,P<0.01). These results indicated that topical application, of PCF provided broad solar UV spectrum photoprotection; and that the antioxidant property of PCF might play a role in photoprotection. Project No. 39970638 supported by the NSFC, and the Science and Technology Bureau of Qingdao (No. 2001-28-50).  相似文献   

Modelling of deformation response and chemo‐mechanical coupling in chalk     

S. Pietruszczak  D. Lydzba  J. F. Shao 《国际地质力学数值与分析法杂志》2006,30(10):997-1018

A constitutive relation is derived for describing the mechanical response of chalk. The approach is based on a phenomenological framework which employs chemo‐plasticity. The properties of the material are assumed to be affected by the physico‐chemical processes that occur through the interaction between the skeleton and the pore fluid. The underlying mechanism is discussed by invoking a micromechanical analysis. The performance of the framework is illustrated by examining the evolution of mechanical characteristics in the presence of different pore fluids. Copyright © 2006 John Wiley & Sons, Ltd.  相似文献   

    

A. S. Belyakov  V. S. Lavrov  A. V. Nikolaev  L. L. Khudzinskii 《Doklady Earth Sciences》2006,407(2):258

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胶东“玲珑-焦家式”金矿资源潜力与找矿   总被引：1，自引：1，他引：0  

李士先  王建收 《山东国土资源》2006,22(12):36-41

“玲珑焦家式”金矿的成岩成矿,从新太古代至中生代存在着继承性的成因关系,成矿具有长期性、多源性特点,但中生代燕山早期岩浆活动是主导成矿因素。区域化探成果显示胶东金矿直接矿源岩———郭家岭花岗岩金的丰度比原始矿源岩———早前寒武纪变质沉积岩系及侵入岩系金的丰度低1/2。郭家岭花岗岩面积在2 km2以上岩体定量估计金亏损总量与胶东金矿总量预测的资源量相当,从一个侧面展现了胶东金矿资源的潜力。望儿山金矿的找矿实践展示,焦家式金矿在1 000 m以下尚有巨大潜力,整个胶东金矿产区在3 000 m以上的资源潜力应在5000 t以上。  相似文献   

Application of Grain Size Analysis to Study Sedimentary Environment of Sand Dune in the Vicinity of Tumen River     

Feng Ma  Li Liu  Lin Cao 《东北亚地学研究》2003,(1)

The dunes in estuary of Tumen River in China lie to the area between the Jiushaping and Fangchuan in the left bank of Tumen River (Fig.1). The dis-tance is about 15～20 km between the dunes and the coast. It ranges from China to D. P. R. Korea and Russia. The range of the height of dunes is about 15～20 m and the width is 100～200 m. By the re-connaissance, we protracted 9 section planes of the dunes and collected 40 sand samples of the dunes, and identified the sedimentary environment …  相似文献   

应用GPS观测青藏高原东北缘应力场变化   总被引：2，自引：0，他引：2  

张永志  胡斌  陈宏宾 《地球科学与环境学报》2003,25(4):80-84

采用各向同性弹性地球模型推导了地面位移场速率与地壳内任意点应力场变化的边界积分关系,同时利用青藏高原东北缘1999～2001年观测的GPS资料对观测区地壳深度为5 km和25 km的主应力和最大剪应力进行了计算分析.结果表明,青藏高原东北缘的主应力变化主要集中在祁连山断裂、海原断裂等,在1920～1954年间历史上发生过多次震级为7.0～8.5级强震的断裂附近,并具有主应力变化沿断层走向分布、最大剪应力沿断层走向交替变化等特征.  相似文献   

Geological environment conflicts of Kunming Basin and its urban sustainable development     

Jianhua FAN Bingfei SHI 《东北亚地学研究》2006,9(2):217-219

Kunming Basin locates middle of Yunnan altiplano and has a particularity in geography,topographic and geological environment.With the urban dilation quickly,add the reason of the unreasonable city layout,conflicts between environment and urban resources consumption become shrill increasingly.It is human being activities that lead to vulnerability and depravation of geological environment in local.Take a few examples on geological environment to expatiate relationship between urban construction and geological environment carrying capacity,and find a way how to make a better plan for urban sustainable development to achieve new balance between man and nature in local.  相似文献   

超基性岩中含铜、钴块状硫化物矿床——德尔尼铜矿成因新认识   总被引：1，自引：0，他引：1  

章午生  陈杰 《青海国土经略》1996,(1)

长期以来对德尔尼铜矿的成因存在着不同认识。从矿石组成和结构、构造来看,应属典型的块状硫化物矿石,矿床亦应属于含铜黄铁矿型矿床。但从其地质产状来看又与一般的黄铁矿型矿床大不相同,与一般的岩浆熔离铜镍硫化物矿床也有较多差异。这就是本矿床类型独特之处。近年来通过工作又取得一些新资料,特别是超基性岩和矿石的同位素年龄数据。本文在综合新老资料基础上,提出新看法,认为该矿床形成于上地幔,再就位于地壳浅部。其成因类型暂定为:“深部熔离—构造侵位矿床”。鉴于本矿床与一般块状硫化物矿床相比有其独特性,建议命名为“德尔尼型”。  相似文献   

成团天体系统成员概率计算的有效性问题     

邵正义  赵君亮 《天文学报》1996,37(4):377-386

本文提出了一个普适的衡量成团天体系统成员概率计算结果的有效性指数：Ｅ＝１－ＮΣ｛Ｐ（ｉ）［１－Ｐ（ｉ）］｝／ΣＰ（ｉ）Σ［１－Ｐ（ｉ）］｝，并以此对以Ｓａｎｄｅｒｓ方法为基础的各种成员确定模型的有效性进行了分析．从总体上说，运动学资料（自行、视向速度等）是一类有效的观测判据．  相似文献   

南海北缘北东东向构造活动性研究     

任镇寰  任奔滔  罗振暖  陈益明  钟贻军 《大地测量与地球动力学》1996,(2)

从地形地貌特征、重磁地球物理场、深部构造与断裂构造以及地震活动、震源机制等多方面论述北东东向构造是南海北缘的主要活动构造。对于长期以来认为新华夏系北东向构造是该区主要活动构造的观点来说，这是一种新的学术思想。  相似文献