基于数据挖掘探析现代湖湘名中医治疗肺癌的用药规律          下载免费PDF全文

刘珍  刘馨怡  金禹辰 《应用海洋学学报》2023,39(7):41

目的：基于数据挖掘技术探析现代湖湘名中医治疗肺癌的用药规律。方法：通过计算机检索2000年1月1日至2023年5月31日中国知网（CNKI）、万方数据(WANFANG DATA)、维普中文科技期刊数据库（VIP）中关于现代湖湘名中医治疗肺癌的相关病案,使用Excel 2016、IBM SPSS Modeler 18.0、IBM SPSS Statistics 25.0软件进行药物频次、性味归经、功效、关联规则及核心药物聚类分析。结果：共纳入处方111首,中药290味,累计用药频次为1690次。高频药物24味（使用频次≥18次）,排前10位的药物依次为甘草、黄芪、白花蛇舌草、法半夏、茯苓、白术、浙贝母、麦冬、桑白皮、半枝莲。四气以寒、温、平为主;五味以苦、甘、辛为主;归经以归肝、肺、胃、脾经为主,功效以活血散瘀、行气止痛、清热解毒为主。关联规则分析得到核心药物26组,其中二联组合2组,三联组合24组。聚类分析得到核心组方5首。结论：现代湖湘名中医论治肺癌多从肝、肺、胃、脾论治,选用苦寒之品清热解毒,辅以甘温之品补益正气,治以活血散瘀、行气止痛、清热解毒、扶正益气为法,为肺癌的临床治疗提供了依据与参考。  相似文献   

淀山湖蓝藻水华高发期叶绿素a动态及相关环境因子分析   总被引：22，自引：3，他引：19  

吴阿娜  朱梦杰  汤琳  朱刚  汪琴  张锦平 《湖泊科学》2011,23(1):67-72

根据2008年5-9月专项监测数据,分析蓝藻水华高发期淀山湖叶绿素a浓度的动态变化,及其与pH、溶解氧、TN、TP等环境因子的相互关系.结果表明,淀山湖蓝藻水华高发期叶绿素a存在明显的时间变化和空间分异,特别是叶绿素a的峰值共对应了3次水华暴发过程.其叶绿素a对数与总磷对数呈极显著正相关,与硝酸盐氮、TN/TP呈负相关...  相似文献   

巢湖四条入湖河流硝态氮污染来源的氮稳定同位素解析   总被引：6，自引：1，他引：5  

刘姝  孔繁翔  蔡元锋  阳振  王济奎  史小丽 《湖泊科学》2012,24(6):952-956

采用氮稳定同位素技术对巢湖四条主要污染输入河流(南淝河、十五里河、派河和双桥河)的氮污染状况和硝态氮来源进行研究.结果表明,巢湖四条入湖河流氮污染最严重的是十五里河,其次是南淝河和派河,双桥河的污染相对较轻.硝态氮的稳定同位素分析结果表明,巢湖四条入湖河流的硝态氮污染物在季节上受到不同因子的影响.十五里河和南淝河的硝态氮污染主要来源于城市生活污水和工业废水;派河的硝态氮污染在冬季主要来源于工业废水,春季来源于农业面源,而在夏季主要受到雨水的影响;双桥河的硝态氮污染冬、春季主要来源于农业面源,夏季主要受雨水的影响.此外本研究结果还表明巢湖四条主要入湖河流的氮污染源主要为铵态氮,因此今后要对铵态氮的来源进行同位素示踪.  相似文献   

青海湖热力状况的模拟与未来情景之研究   总被引：5，自引：2，他引：3  

秦伯强  黄群 《湖泊科学》1998,10(3):25-31

运用基于湖泊热量收支与湍流扩散的湖泊热力学模型模拟了青海湖近３０年来湖水热力状况,内容包括湖泊水面温度,温度沿深度的垂直分布,冬季结冰与融冰的起迄时间,冰盖厚度;积雪深度与天数等。在此基础上,运用４个ＧＣＭｓ模型输出的ＣＯ２倍增情景下该地区的气候状况,评价了湖泊热力状况在未来的可能变化情况。  相似文献   

延安地区上三叠统长6期沉积特征及其演化   总被引：1，自引：0，他引：1  

王震  吴汉宁  李英  王靖华  柏冠军  赵希刚 《煤田地质与勘探》2005,33(6):17-20

通过对川口油田测井曲线和岩心分析,总结了延安地区上三叠统长6期沉积微相特征,建立了长6期岩性和测井曲线的响应模式。再结合分析沉积的演化过程、电性和物性特征、骨架砂体的几何形态和沉积演变,得出该地区沉积相和演化模式。认为从长6₄到长6₁期沉积环境为湖泊、三角洲前缘、三角洲平原亚相到河流相。长6₁、长6₂是主力储层,其物性最好。   相似文献   

2016年3月21日金塔县M_S 4.7地震强震动记录分析     

徐钦  田秀丰  潘章容  张卫东  袁洁 《地震地磁观测与研究》2017,38(2):94-97

2016年3月21日11时29分甘肃省酒泉市金塔县发生M_S 4.7地震,甘肃省强震动台网中心收集到5组三分向加速度记录,常规处理后得到15条零基线校正后的三分向峰值加速度(PGA),选取土层台基类型的62XID台站加速度记录(PGA数值最大)进行分析,绘制校正后的加速度、速度和位移时程曲线及加速度反应谱,为中国西部工程震害调查提供参考资料。  相似文献   

Identification and assessment of water safety risk for groundwater recharge with reclaimed water in China     

Zhen?Li  Chongqing?Xu  Miao?LiEmail author  Guihuan?Yan  Xiang?LiuEmail author  Yeping?Ma 《Stochastic Environmental Research and Risk Assessment (SERRA)》2017,31(7):1671-1682

Groundwater recharge using reclaimed water has developed rapidly around the world to relieve the groundwater resource shortage and declining of the water table. Traditional water treatment systems are inefficient to remove all the types of contaminants, so it is urgent to identify the priority chemical substances (CSs) that deserve our first concern. In this study, we developed a method (EER method) to identify priority CSs in groundwater recharge by surface spreading and direct aquifer injection. Three stages were processed which were exposure assessment, effect assessment and ranking for identification of priority CSs. Fourteen cities in China were selected for data collected and 90 pollutants in reclaimed water samples were analyzed as the target pollutants for a case study. According to three stages, the 90 CSs studied were divided into five groups (primary control CSs and high, moderate and low and no risk control CSs). In the primary control CSs and high, moderate and low and no risk control CSs group there were 14, 18, 21, 21 and 16 CSs, respectively when groundwater recharged by surface spreading, while there were 15, 18, 21, 21 and 15 CSs when recharged by direct injection. This method provided an indicator of prioritizing the risk of 90 compounds in the reclaimed water for groundwater recharge.  相似文献   

Study of a smart platform based on backstepping control method     

Luyu Li  Baowei Cheng  Yu Zhang  Han Qin 《地震工程与工程振动(英文版)》2017,16(3):599-608

A structural model is significant for the verification of structural control algorithms. However, for nonlinear behavior, experiments are mostly destructive tests that are costly, and conducting repetitive structural experiments is difficult. Therefore, a repetitive structural vibration model is important for structural vibration control. In this study, a smart platform to realize different structural behaviors is developed based on the backstepping control algorithm. Lyapunov functions are used to derive the control law. Simulations show that the designed model can track the structural responses of different arbitrary linear structures very well. In addition, the proposed platform can track responses of different piecewise linear structures and desired models with various hysteresis very well. Numerical results verify the effectiveness of the proposed tracking controller through the backstepping method for the established platform.  相似文献   

Frequency-dependent rupture process,stress change,and seismogenic mechanism of the 25 April 2015 Nepal Gorkha <Emphasis Type="Italic">M</Emphasis><Subscript>w</Subscript> 7.8 earthquake     

JiuXun Yin  HuaJian Yao  HongFeng Yang  Jing Liu  WeiZe Qin  HaiJiang Zhang 《中国科学:地球科学(英文版)》2017,60(4):796-808

On 25 April 2015, an M _w 7.8 earthquake occurred on the Main Himalaya Thrust fault with a dip angle of ~ 7° about 77 km northwest of Kathmandu, Nepal. This Nepal Gorkha event is the largest one on the Himalayan thrust belt since 1950. Here we use the compressive sensing method in the frequency domain to track the seismic radiation and rupture process of this event using teleseismic P waves recorded by array stations in North America. We also compute the distribution of static shear stress changes on the fault plane from a coseismic slip model. Our results indicate a dominant east-southeastward unilateral rupture process from the epicenter with an average rupture speed of ~3 km s^?1. Coseismic radiation of this earthquake shows clear frequency-dependent features. The lower frequency (0.05–0.3 Hz) radiation mainly originates from large coseismic slip regions with negative coseismic shear stress changes. In comparison, higher frequency (0.3–0.6 Hz) radiation appears to be from the down-dip part around the margin of large slip areas, which has been loaded and presents positive coseismic shear stress changes. We propose an asperity model to interpret this Nepal earthquake sequence and compare the frequency-dependent coseismic radiation with that in subduction zones. Such frequency-dependent radiation indicates the depth-varying frictional properties on the plate interface of the Nepal section in the main Himalaya thrust system, similar to previous findings in oceanic subduction zones. Our findings provide further evidence of the spatial correlation between changes of static stress status on the fault plane and the observed frequency-dependent coseismic radiation during large earthquakes. Our results show that the frequency-dependent coseismic radiation is not only found for megathrust earthquakes in the oceanic subduction environment, but also holds true for thrust events in the continental collision zone.  相似文献   

Snowdrift effect on snow deposition: Insights from a comparison of a snow pit profile and meteorological observations in east Antarctica     

MingHu Ding  Tong Zhang  CunDe Xiao  ChuanJin Li  Bo Jin  LinGen Bian  ShuJie Wang  DongQi Zhang  DaHe Qin 《中国科学:地球科学(英文版)》2017,60(4):672-685

A high-frequency and precise ultrasonic sounder was used to monitor precipitated/deposited and drift snow events over a 3-year period(17 January 2005 to 4 January 2008) at the Eagle automatic weather station site,inland Antarctica.Ion species and oxygen isotope ratios were also generated from a snow pit below the sensor.These accumulation and snowdrift events were used to examine the synchronism with seasonal variations of δ~(18)O and ion species,providing an opportunity to assess the snowdrift effect in typical Antarctic inland conditions.There were up to 1-year differences for this 3-year-long snow pit between the traditional dating method and ultrasonic records.This difference implies that in areas with low accumulation or high wind,the snowdrift effect can induce abnormal disturbances on snow deposition.The snowdrift effect should be seriously taken into account for high-resolution dating of ice cores and estimation of surface mass balance,especially when the morphology of most Antarctic inland areas is similar to that of the Eagle site.  相似文献