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11.
Polybrominated diphenyl ethers (PBDEs) are now found ubiquitously in the aquatic environment and biota, and there is a growing concern that PBDEs may disrupt endocrine systems, leading to reproductive impairments of aquatic animals. In our study, zebrafish (Danio rerio) were exposed to the 5 ng/L, 1 μg/L and 50 μg/L of DE-71 for the duration of the whole life cycle (120 days, from eggs to adults). The expression of selected genes along the brain-pituitary-gonadal (BPG) axis and liver, and the levels of plasma sex hormones were examined. In male fish, up-regulation of GnRH in brain, FSHβ and LHβ in pituitary, FSH-receptor, LH-receptor, and CYP19a in testis was clearly evident, while down-regulation of CYP11a and 3β-HSD was found in testis. In female fish, a 2.4-fold up-regulation of 3β-HSD was found in ovary upon exposure to 50 μg/L of DE-71. GnRH in brain, FSHβ and LHβ in pituitary were also up-regulated, while ERβ, TH and TPH in brain and GnRH-receptor in pituitary were significantly down-regulated. Hepatic ERα, AR and VTG in males were all down-regulated, while hepatic ERα and AR in female were up-regulated. Serum estradiol (E2) was reduced in both male and female upon exposure to DE-71, while significant increases in serum testosterone (T) and 11-keto-testosterone (11-KT) were only found in male but not female fish. The ratio of T/E2 as well as the ratio of 11-KT/E2 in male fish increased in a dose-dependent manner upon exposure to DE-71. Our overall results showed that whole life exposure of DE-71 altered the expression of regulatory genes and receptors at all three levels of the BPG axis in zebrafish, and the responses are sex dependent. The observed disruption of GnRH and GtHs can be further related to the subsequent disruption in both levels and balance sex steroid hormones. 相似文献
12.
The organic geochemistry of oil seeps from the Sierra de Perijá eastern foothills, Lake Maracaibo Basin, Venezuela 总被引：1，自引：0，他引：1
M. Escobar G. MárquezS. Inciarte J. RojasI. Esteves G. Malandrino 《Organic Geochemistry》2011,42(7):727-738
The organic geochemistry of samples from 11 oil seeps was studied. The samples were collected from the Cachirí area, Carboniferous Region of Tulé (Lake Maracaibo Basin, Venezuela), associated with the Tigre Fault. Biomarkers (hopanes, steranes, n-alkanes, acyclic isoprenoids, and aromatic steroids) were analyzed using gas chromatography-mass spectrometry (GC-MS). These hydrocarbon rich fluids have undergone biodegradation (2-6 on the Peters and Moldowan scale), showing both the partial loss of n-alkanes and the microbial degradation of isoprenoids and steranes. These oil seeps were generated from a mature calcareous source rock that was deposited in a marine paleoenvironment under reducing conditions. Moreover, these seeps are likely derived from the Cretaceous La Luna Formation that reached a level of maturity near the peak of oil generation in the study area. The nature of the studied oil seeps, together with the oil generation models reported for this rock unit in the study area, suggests that these oils are a mixture of an initially heavy, altered oil and a second migrated light crude oil resulting from two generation pulses from the La Luna Formation. Evidence for the presence of light oil trapped in the study area should prompt re-exploration in the northwestern coast of Lake Maracaibo in shallow reservoirs, previously discarded because they usually demonstrated a lack of light oils. 相似文献
13.
Jean-Christophe Pouget David Proaño Andrea Vera Marcos Villacís Thomas Condom Marisa Escobar 《水文科学杂志》2017,62(3):431-446
La forte croissance socio-économique de Quito a conduit à d’importants projets de transferts interbassins, intensifiant la mobilisation des ressources d’altitude situées dans des zones écologiques sensibles et connaissant une fonte accélérée des glaciers. Afin d’étudier divers scénarios d’évolutions, nous proposons une modélisation du continuum climat/glacier/hydrologie/gestion des ressources en eau. Utilisant l’outil Water Evaluation and Planning (WEAP), nous avons développé : (1) une modélisation hydro-climatologique semi-distribuée avec des données mensuelles homogénéisées par vectorisation régionale ; (2) une modélisation de la production en eau des glaciers et de leur évolution interannuelle ; (3) une modélisation en unités hydrologiques distinguant différentes couvertures de sols ; et (4) une modélisation de la gestion distinguant droits, allocation et usages de l’eau. Nous présentons les résultats du calage hydrologique mensuel (1963–2006), en étudiant particulièrement l’équifinalité de diverses paramétrisations. Nous montrons la souplesse, la robustesse et les limites de la modélisation proposée, contribuant à cerner différentes incertitudes dans l’évaluation de scénarios prospectifs. 相似文献
14.
A study on the seismic performance of asymmetric structures with non-linear behaviour and random properties is presented. The structural response of single-storey models, designed using different code criteria is studied using both a deterministic and a probabilistic approach. The worst structural behaviour, in terms of ductility demands, is obtained for symmetric models considering uncertain properties. It is shown that an arbitrary increase of the total lateral strength of the structures does not lead to an increment of the structural safety proportional to the total lateral strength increase, implying that an expensive structure is not always the safest. © 1998 John Wiley & Sons, Ltd. 相似文献
15.
Jacinto GS Sotto LP Senal MI San Diego-McGlone ML Escobar MT Amano A Miller TW 《Marine pollution bulletin》2011,63(5-12):243-248
Herein we present results from one of the first extensive bay-wide oceanographic surveys of Manila Bay, wherein 31 stations were sampled during the northeast monsoon (cold and dry season). A band of hypoxic bottom water (dissolved oxygen<2.8 mg/L) spanned the midsection of the bay from east to west. Bottom nitrate concentrations (5.7-16.8 μM; avg. 11.1 μM) and total organic carbon values in sediments (1.7-3.1%; avg. 2.4%) were high in the midsection, which coincided with the band of hypoxic bottom water. Physical processes and site-specific accumulation of organic material likely lead to hypoxic conditions in Manila Bay, even during the northeast monsoon period when the water column is relatively well mixed. The results of this study complement the previously reported widespread hypoxia that occurs during the rainy season. Thus, hypoxia may be pervasive in the bay throughout the year, although it varies in intensity and spatial extent. 相似文献
16.
Pablo Iribarren Anacona Kevin Norton Andrew Mackintosh Fernando Escobar Simon Allen Bruno Mazzorana Marius Schaefer 《Natural Hazards》2018,92(1):93-112
The rise of total water levels at the coast is caused primarily by three factors that encompass storm surges, tides and wind waves. The accuracy of total water elevation (TWE) forecast depends not only on the cyclonic track and its intensity, but also on the spatial distribution of winds which include its speed and direction. In the present study, the cyclonic winds are validated using buoy winds for the recent cyclones formed in the Bay of Bengal since 2010 using Jelesnianski wind scheme. It is found that the cyclonic winds computed from the scheme show an underestimate in the magnitude and also a mismatch in its direction. Hence, the wind scheme is suitably modified based on the buoy observations available at different locations using a power law which reduces the exponential decay of winds by about 30%. Moreover, the cyclonic wind direction is also corrected by suitably modifying its inflow angle. The significance of modified exponential factor and inflow angle in the computation cyclonic winds is highlighted using statistical analysis. A hydrodynamic finite element-based Advanced Circulation 2D depth integrated (ADCIRC-2DDI) model is used here to compute TWE as a response to combined effect of cyclonic winds and astronomical tides. As contribution of wave setup plays an important role near the coast, a coupled ADCIRC + SWAN is used to perceive the contribution of wind waves on the TWE. The experiments are performed to validate computed surge residuals with available tide gauge data. On comparison of observed surge residuals with the simulations using modified winds from the uncoupled and coupled models, it is found that the simulated surge residuals are better compared, especially with the inclusion of wave effect through the coupled model. 相似文献
17.
Maria I. Velez Jason H. Curtis Mark Brenner Jaime Escobar Barbara W. Leyden Marion Popenoe de Hatch 《Geoarchaeology》2011,26(3):346-364
We inferred the late Holocene environmental history of the Guatemala highlands from multiple lines of evidence in a sediment core from Lake Amatitlán. Inferred environmental changes are generally synchronous with archaeologically documented highland Maya cultural shifts. Population increases in the Middle Preclassic, Early Classic, and Late Postclassic are associated with deforestation and soil erosion. Land abandonment in the Late Preclassic, Late Classic, and Early Postclassic is associated with evidence for reforestation and soil stabilization. Diatoms indicate relatively lower lake level and greater trophic status at times of reduced human impact, from ca. 250 B.C. to A.D. 125 and from ca. A.D. 875 to 1375. Decreased water levels were probably due to drier climate, to reforestation, or both. Lake eutrophication was caused by reduced water volume combined with a legacy of long‐term agricultural activity. Our data contribute to the understanding of relations among ancient Maya culture, climate, and environment. © 2011 Wiley Periodicals, Inc. 相似文献
18.
Jaime Escobar Mark Brenner Thomas J. Whitmore William F. Kenney Jason H. Curtis 《Journal of Paleolimnology》2008,40(2):715-731
Fifty-seven surface sediment samples from 35 Florida lakes were collected to study testate amoebae. Seven genera, 17 species,
and 28 strains were identified in the 46 sediment samples from 31 lakes that contained testate rhizopods. Seven species accounted
for ≥90% of the individuals in all samples. Sediment total phosphorus (TPsed), organic matter (OM), and total carbon:total
nitrogen ratio (TC:TN) were measured to assess the effect of these variables on thecamoebian assemblages. OM content was the
only sediment variable that influenced presence/absence of thecamoebians. Samples with <5% OM contained no thecamoebians.
Lakes with multiple surface sediment samples showed high Morisita–Horn similarity values (0.74–0.99), indicating that all
sites at which samples were collected in a lake provided representative thecamoebian assemblages. No relationship was observed
between thecamoebian diversity indices and sediment variables. Lake trophic state and pH were examined to explore potential
water column influences on thecamoebian communities. Highest thecamoebian diversity indices were found in mesotrophic to eutrophic
lakes with pH near 8.0. These results suggest that water column conditions have a greater influence on thecamoebian assemblages
than do sediment variables. We used multivariate analysis to evaluate the relations between water quality variables and testate
rhizopod assemblages. Canonical correspondence analysis (CCA) showed that alkalinity and pH are the water column variables
that most influence the relative abundance of species. Thecamoebians thus hold promise as bioindicators of acidification in
Florida lakes. Thecamoebian remains in lake sediment cores should be useful to infer past anthropogenic shifts in lake pH. 相似文献
19.
The EGM08 geopotential model complete to degree and order 2159 was used in a remove-compute-restore (RCR) method for the geoid
computation in the State of Rio de Janeiro, Brazil. Terrain and indirect effect corrections were computed using a 6-arcsec
resolution DTE, derived from the TOPODATA Project (Shuttle Radar Topography Mission data) raised by the National Institute
for Space Research. INPE, Brazil. We applied Voronoi/Delaunay discretisations for discrete Stokes integration. In these schemes,
target area is partitioned into polygons/triangles, respectively, and the computation is carried out by point-wise numerical
integration and no gridding is mandatory. For both procedures, the cells were produced using either observed gravity data
combined with gridded Bouguer derived information. Particularly in Delaunay scheme, as the gravity anomalies are interpolated
into the triangular cells, and geoid undulations are computed for their vertices, Stokes function singularity was gone. Externally
estimated errors resulting from a comparison with GPS/leveling data were presented for both the schemes and classical ones,
as well as for the EGM08 undulations. They yielded RMS differences equal to 0.105 m, 0.110 m, 0.110 m, 0.115 m and 0.228 m,
respectively, for Voronoi, Delaunay, Voronoi/Delaunay with gridded-data alone and EGM08, computed between 32 GPS/leveling
points. 相似文献
20.
Dagoberto Escobar Carlos R. Fadragas Genly Leon Yoelsy Leyva 《Astrophysics and Space Science》2014,349(1):575-602
In this work we present a phase space analysis of a quintessence field and a perfect fluid trapped in a Randall-Sundrum’s Braneworld of type 2. We consider a homogeneous but anisotropic Bianchi I brane geometry. Moreover, we consider the effect of the projection of the five-dimensional Weyl tensor onto the three-brane in the form of a negative Dark Radiation term. For the treatment of the potential we use the “Method of f-devisers” that allows investigating arbitrary potentials in a phase space. We present general conditions on the potential in order to obtain the stability of standard 4D and non-standard 5D de Sitter solutions, and we provide the stability conditions for both scalar field-matter scaling solutions, scalar field-dark radiation solutions and scalar field-dominated solutions. We find that the shear-dominated solutions are unstable (particularly, contracting shear-dominated solutions are of saddle type). As a main difference with our previous work, the traditionally ever-expanding models could potentially re-collapse due to the negativity of the dark radiation. Additionally, our system admits a large class of static solutions that are of saddle type. These kinds of solutions are important at intermediate stages in the evolution of the universe, since they allow the transition from contracting to expanding models and viceversa. New features of our scenario are the existence of a bounce and a turnaround, which lead to cyclic behavior, that are not allowed in Bianchi I branes with positive dark radiation term. Finally, as specific examples we consider the potentials V∝sinh?α (β?) and V∝[cosh(ξ?)?1] which have simple f-devisers. 相似文献