An aromatase inhibitor and tamoxifen decrease plasma levels of o,p'-DDT and its metabolites in Nile tilapia (Oreochromis niloticus)     

Leaños-Castañeda O  Gold-Bouchot G  Van Der Kraak G  Lister A  Ceja-Moreno V  Simá-Alvarez R 《Marine environmental research》2004,58(2-5):337-342

The objective of this study was to determine if tamoxifen or an aromatase inhibitor (4-hydroxyandrostenedione; 4-OHA) affected plasma concentrations of o,p' -DDT and its metabolites, o,p'-DDD and o,p'-DDE, in mature tilapia. Male and female tilapia were injected 6 times intraperitoneally with o,p'-DDT (40 mg/kg) alone or in combination with 4-OHA (2 mg/kg) over a 12 day period. An additional group of male fish was injected with tamoxifen (5 mg/kg) plus o,p'-DDT. At the end of the treatment period, plasma samples were extracted and analyzed by GC/ECD. Females injected only with o,p'-DDT had significantly higher levels of o,p'-DDT compared with males. Interestingly, females and males treated concomitantly with o,p'-DDT and 4-OHA or tamoxifen had significantly lower concentrations of plasma o,p'-DDT (about 50%) compared with fish treated with only o,p'-DDT. These initial results suggest that an interaction between endocrine-active compounds occurs in vivo in tilapia and may involve alterations in metabolism of o,p'-DDT.  相似文献   

Seasonal and annual variations of marine sinking particulate flux during 1993~1996 in the central South China Sea   总被引：1，自引：0，他引：1  

CHEN Ronghu  WIESNER M G  ZHENG Yulong  CHENG Xinrong  JIN Haiyan  ZHAO Qingying  ZHENG Lianfu 《海洋学报(英文版)》2007,26(3):33-43

A total of 67 samples from the upper and lower sediment traps in the central South China Sea were analyzed, which were collected during 1993~1996. It is indicated that the distribution of stable isotope values, surface primary productivity, fluxes of total particulate matter, carbonate, biogenic opal, organic carbon, planktonic foraminiferal species and their total amount exhibit obviously seasonal and annual fluctuations. High values of the fluxes occurred in the prevailing periods of the northeastern and southwestern monsoons, and the low values occurred during the periods between the two monsoons. The fluxes of some planktonic foraminiferal species (Globigerinoides sacculifer, G. ruber, Globigerinita glutinata, Neogloboquadrina dutertrei) and their percentages also exhibit two prominent peaks during the prevailing periods of the northeastern and southwestern monsoons respectively, while those of Globigerina bulloides, Globorotalia menardii and Pulleniatina obliquiloculata only exhibit one peak in the prevailing periods of the northeastern monsoon. In addition, fluxes and percentages of Globigerinoides sacculifer and Globorotalia menardii as well as the fluxes of carbonate and total amount of planktonic foraminifera decrease gradually from 1993 to 1996, and those of Globigerina bulloides, Globigerinita glutinata and biogenic opal increase gradually from 1993 to 1996. The fluxes of carbonate and organic carbon in the upper trap are higher than those in the lower one. The study indicates that the seasonal and annual variations of the sediment fluxes and planktonic foraminiferal species are mainly controlled by the changes of surface primary productivity and hydrological conditions related to the East Asian monsoon. The lower carbonate and organic carbon fluxes in the lower trap are related to the dissolution.  相似文献   

Variations of antioxidant efficiency and presence of endosymbiotic diatoms in the Antarctic porifera Haliclona dancoi     

Regoli F  Nigro M  Chierici E  Cerrano C  Schiapparelli S  Totti C  Bavestrello G 《Marine environmental research》2004,58(2-5):637-640

The role of endosymbiotic diatoms as pro-oxidant stressors in porifera has been investigated in the Antarctic sponge Haliclona dancoi in which the presence of diatoms is influenced by marked seasonal variations during the austral summer. Both chlorophaeopigments and frustules were absent in sponge tissues sampled in early November at the beginning of the summer and increased from the mid of December with slightly shifted temporal trends. The efficiency of antioxidant defenses in the sponge showed a marked response to symbionts with clearly enhanced values corresponding to the peak of diatoms.  相似文献   

密西西比现代被动边缘海底扇与古活动边缘海底扇两者浊积相组合之比较     

Shaum.  G 守玉 《海洋地质译丛》1989,(6):25-31

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Measurement of DNA single-strand breaks in gill and hemolymph cells of mussels, Mytilus sp., collected on the French Atlantic Coast     

Akcha F  Tanguy A  Leday G  Pelluhet L  Budzinski H  Chiffoleau JF 《Marine environmental research》2004,58(2-5):753-756

DNA single-strand breaks were measured by the comet assay in both gill and hemolymph cells of mussels collected in 3 sampling areas of the French coast (Pointe du Castelli, Pen Bron and Saint-Nazaire Harbour). Whole mussel tissue samples were also collected for the chemical determination of PAH, PCB and heavy metal concentrations. In mussel, a higher level of DNA strand breaks was measured in gill than in hemolymph cells (p < 0.01). Despite a factor of contamination from 2 to 3 between sites, no difference in the extent of mussel DNA strand breaks was shown between sampling locations (p > 0.05), questioning the sensitivity of the assays used in biomonitoring studies.  相似文献   

Oxidative stress in ecotoxicology: from the analysis of individual antioxidants to a more integrated approach     

Regoli F  Gorbi S  Frenzilli G  Nigro M  Corsi I  Focardi S  Winston GW 《Marine environmental research》2002,54(3-5):419-423

An integrate approach will be discussed for investigations on oxidative stress in xenobiotic toxicity. While the analysis of individual antioxidants is useful for their sensitivity and to understand the mode of action of a stressor, the integration with the analysis of the total antioxidant capacity provides a more holistic assessment of the overall biological significance of such variations. TOSC has a greater predictive value on the health condition of the organisms and allows to discriminate the different role of specific ROS in oxidative stress syndrome.  相似文献   

南极威德尔海陆缘固冰区叶绿素a及硅藻的分布     

陈兴群  G.迪克曼 《海洋学报》1989,11(4):501-509

本文描述了1985年1月-2月联邦德国“极星”号极地考察船沿威德尔海陆缘固冰区调查期间所获得的冰柱状样内叶绿素a以及硅藻的分布,对三个不同区域柱状样的分析结果表明,底部10-30cm的海冰多呈褐色,其内由大量藻类,特别是由硅藻细胞的富集而形成,丰度变化大.在融化的底部冰样中,细胞数高达10⁸个/l,叶绿素a浓度高达2220mg/m³,中部常见到大量小型的失去色素乃至死亡的硅藻细胞.初步鉴定出26种硅藻,其多数隶属于茧形藻属(Amphiprora),斜纹,藻属(Pleurosigma),菱形藻属(Nitzschia),盒形藻属(Biddulphia),角刺藻属(Corethron),海毛藻属(Thalassiothrix),海链藻属(Thalassiosira),以及脆杆藻属(Fragilaria)等,本文还记录了两种不同的底部生态群落:寡种和多种集群的生态类型,并对硅藻的富集和分布成因作了一些讨论.  相似文献   

Different cardiac response to copper in limpets from metal polluted and clean shores of Hong Kong     

Chelazzi G  De Pirro M  Williams GA 《Marine environmental research》2004,58(1):83-93

The gastropod limpet, Cellana grata, is common on moderately exposed to exposed Hong Kong rocky shores. On the basis of the existing literature on trace metal contamination in Hong Kong, four sites were identified, representative of highly polluted (Aberdeen and Lei Yue Mun) and clean (Cape d'Aguilar and Clear Water Bay) conditions. Limpets from the two polluted sites showed similar, but significantly higher body concentrations of copper than limpets from the two clean sites, which were also similar. Non-invasive measurements of cardiac activity of limpets from the four sites showed between site differences in baseline heart rates under standard seawater, irrespective of pollution level. When acutely exposed to water borne copper (2 h, 0.5+/-0.06 SD ppm), however, limpets from clean sites showed a significantly higher increase in inter-beating time (bradycardia) than those from polluted sites. These results highlight the potential use of cardiac activity to assess the exposure of natural populations of limpets to trace metal pollution.  相似文献   

Population structure of Haliotis rubra from South Australia inferred from nuclear and mtDNA analyses   总被引：1，自引：0，他引：1  

LI Zhongbao  Sharon A Appleyar  Nicholas G Elliott 《海洋学报(英文版)》2006,25(4):99-112

1Introduction ThemajorityofAustralia’sabalonefisheryex ports(5.135kt,worth＄216millionin2002～2003,ABARE2004)consistofblacklipabalone(HaliotisrubraLeach,1814).AssuchH.rubrais consideredasanimportantmarineresourcewithin Australia.Likemanyabalonespecieswor…  相似文献   

Bacterial killing by Mytilus hemocyte monolayers as a model for investigating the signaling pathways involved in mussel immune defence     

Canesi L  Scarpato A  Betti M  Ciacci C  Pruzzo C  Gallo G 《Marine environmental research》2002,54(3-5):547-551

The signaling pathways involved in mussel immune defence were investigated utilizing a model of killing of Escherichia coli by Mytilus galloprovincialis hemocytes in a co-culture setting. In particular, the role played by different mitogen activated protein kinases (MAPKs) and by the production of eicosanoids were investigated utilising specific cell permeant, pharmacological enzyme inhibitors. Hemocyte pretreatment with the p38 MAPK inhibitor SB203580 significantly reduced bacterial killing, whereas PD98059 (an inhibitor of ERK--extracellularly regulated kinase--MAPK activation) had no significant effect. Wortmannin also inhibited bacterial killing, indicating a crucial role for PI3-kinase activation in the immune response. Killing of E. coli was also reduced by inhibitors of both PLA2 and cyclooxygenase activities, indicating that eicosanoid production is involved in mediating the response to bacterial challenge. The results demonstrate that bacterial killing by mussel hemocytes is particularly sensitive to inhibitors of the key steps involved in the transduction of bacterial signals into the host cell. Moreover, these data indicate that the hemocyte bactericidal activity can be suitably utilized not only for identifying the signaling pathways involved in the response to bacterial infection, but also as a potential investigative-toxicology model to test drugs and contaminants for their effect on the overall mussel immune defence.  相似文献