Determinants of species susceptibility to oxidative stress: A comparison of channel catfish and brown bullhead     

Richard T. Di Giulio  Jeff V. Behar  David B. Carlson  Bruce M. Hasspieler  David E. Watson 《Marine environmental research》1995,39(1-4)

Xenobiotic-mediated productions of reactive oxygen species, via enzymemediated redox cycling, have been implicated in a variety of toxicological phenomena including lipid peroxidation, enzyme inactivation and oxidative DNA damage leading to cancer. A comparison was undertaken of two benthic freshwater fish species that appear to differ markedly in their susceptibility to chemical carcinogenesis—the channel catfish (Ictalurus punctatus) and the more cancer-prone brown bullhead (Ameriurus nebulosus)-in terms of basic biochemical characteristics related to oxidative stress. This has included analysis of microsomal redox cycling of model xenobiotics (e.g. menadione) as well as antioxidant and other detoxifying enzymes in hepatic tissue of the two species. In addition, endpoints of oxidative stress, such as altered glutathione status and oxidative DNA damage, were examined. These studies have revealed numerous qualitative and quantitative differences between the two species both in terms of basal enzyme activities and in species response to model prooxidants. For example, bullhead appear to possess a greater capacity for microsomal redox cycling of xenobiotics, but have glutathione-dependent defense systems less able to withstand oxidative challenge. These and other interspecific differences have allowed for an improved understanding of the basic mechanisms which may underly species susceptibility to oxidative stress and critical manifestations such as cancer.  相似文献   

Hydrogeology of the Nurra Region, Sardinia (Italy): basement-cover influences on groundwater occurrence and hydrogeochemistry   总被引：2，自引：0，他引：2  

Giorgio Ghiglieri  Giacomo Oggiano  Maria Dolores Fidelibus  Tamiru Alemayehu  Giulio Barbieri  Antonio Vernier 《Hydrogeology Journal》2009,17(2):447-466

The Nurra district in the Island of Sardinia (Italy) has a Palaeozoic basement and covers, consisting of Mesozoic carbonates, Cenozoic pyroclastic rocks and Quaternary, mainly clastic, sediments. The faulting and folding affecting the covers predominantly control the geomorphology. The morphology of the southern part is controlled by the Tertiary volcanic activity that generated a stack of pyroclastic flows. Geological structures and lithology exert the main control on recharge and groundwater circulation, as well as its availability and quality. The watershed divides do not fit the groundwater divide; the latter is conditioned by open folds and by faults. The Mesozoic folded carbonate sequences contain appreciable amounts of groundwater, particularly where structural lows are generated by synclines and normal faults. The regional groundwater flow has been defined. The investigated groundwater shows relatively high TDS and chloride concentrations which, along with other hydrogeochemical evidence, rules out sea-water intrusion as the cause of high salinity. The high chloride and sulphate concentrations can be related to deep hydrothermal circuits and to Triassic evaporites, respectively. The source water chemistry has been modified by various geochemical processes due to the groundwater–rock interaction, including ion exchange with hydrothermal minerals and clays, incongruent solution of dolomite, and sulphate reduction.  相似文献   

Formal proposal for the Bathonian GSSP (Middle Jurassic) in the Ravin du Bès Section (Bas-Auran, SE France)     

Sixto R. Fernández-López  Giulio Pavia  Elisabetta Erba  Myett Guiomar  Maria H. Henriques  Roberto Lanza  Charles Mangold  Davide Olivero  Daniele Tiraboschi 《Swiss Journal of Geoscience》2009,102(2):271-295

The Bathonian Global Stratotype Section and Point (GSSP) is proposed at the base of limestone bed RB071 (bed 23 in Sturani 1967) in the Ravin du Bès Section (43° 57′ 38′′ N, 6° 18′ 55′′ E), Bas-Auran area, “Alpes de Haute Provence” French department. The Ravin du Bès Section, as formal candidate GSSP for the base of the Bathonian Stage, satisfies most of the requirements recommended by the International Commission on Stratigraphy: 1) The exposure extends over 13 m in thickness. At the Bajocian-Bathonian transition, no vertical (bio-, ichno- or tapho-) facies changes, condensation, stratigraphic gaps or hiatuses have been recorded. Structural complexity, synsedimentary and tectonic disturbances, or important alterations by metamorphism are not relevant constraints. 2) There is a well-preserved, abundant and diverse fossil record across the boundary interval, with key markers (ammonites and nannofossils) for worldwide correlation. The base of the Bathonian Stage and Zigzag Zone in Bas-Auran corresponds to the first occurrence level of Gonolkites convergens Buckman, which coincides with the first occurrence of Morphoceras parvum Wetzel. Calcareous nannofossils, as secondary global marker, are present in all beds and allow characterizing the Bajocian-Bathonian transition. 3) Regional analyses of sequence stratigraphy and manganese chemostratigraphy are available. Spectral gamma-ray data corroborate an Early Bathonian deepening half-cycle of second order. 4) The criteria of accessibility, conservation and protection are assured by the “Réserve Naturelle Géologique de Haute Provence”. The Cabo Mondego Section (Portugal) is suggested as the Bathonian auxiliary section and point (ASSP) within this GSSP proposal.  相似文献   

Immunotoxicity of the xenoestrogen 4-nonylphenol to the cockle Cerastoderma glaucum     

Matozzo V  Rova G  Ricciardi F  Marin MG 《Marine pollution bulletin》2008,57(6-12):453-459

The in vivo effects of 4-nonylphenol (NP) on functional responses of haemocytes from the cockle Cerastoderma glaucum were investigated after 7 days exposure to sublethal NP concentrations (0, 0+acetone, 0.0125, 0.025, 0.05 and 0.1 mg/l NP). Haemocytes from both controls and exposed cockles were collected, and the effects of NP on total haemocyte count (THC) and volume of circulating cells, intracellular superoxide anion (O(2)(-)) levels, acid phosphatase and lysozyme-like activities in both haemocyte lysate (HL) and cell-free haemolymph (CFH) were evaluated. Exposure of cockles to 0.1mg/l NP significantly increased THC (p<0.05) with respect to controls. Analysis of haemocyte size frequency distribution showed that the haemocyte fraction of about 7-8 microm in diameter and 250 femtolitres in volume increased markedly in cockles exposed to the highest NP concentration tested. Apoptosis resulting in cell volume reduction in NP-exposed animals cannot be excluded. No statistically significant variation in intracellular O(2)(-) levels was observed. Conversely, significant increases (p<0.05) in acid phosphatase activity were observed in CFH from 0.05 and 0.1mg/l NP-exposed animals; no significant differences in enzyme activity were recorded in HL. Lysozyme-like activity also increased significantly in CFH from cockles exposed to 0.05 mg/l NP (p<0.05) and 0.1 mg/l NP (p<0.001). Instead, lysozyme-like activity decreased significantly (p<0.05) in the HL of animals exposed to 0.05 mg/lNP. Our results suggest that NP induces variations in the functional responses of haemocytes of C. glaucum, mainly by reducing cell membrane stability and promoting cell degranulation.  相似文献   

The expansion,limit and decline of the global marine fish catch     

Giulio Pontecorvo  William E. Schrank 《Marine Policy》2012

Catch of marine fish grew from after WW II–1989, at which point it stabilized. In 1996 it began to decline. It continues to decline now, at a time when earth's population is expected to reach 10 billion by 2050. Since the factors driving the increase are primarily the growth in income, population, technology of catching fish and ever increasing fishing effort, it is to be expected that the aggregate marine catch will continue to decline. This decline has important implications for marine ecosystems but primarily its importance relates to the human use of other global resources such as food, water and world's climate.  相似文献   

Identification of lateral discontinuities via multi‐offset phase analysis of surface wave data     

Giulio Vignoli  Giorgio Cassiani 《Geophysical Prospecting》2010,58(3):389-413

Surface wave methods are based on the inversion of observed Rayleigh wave phase‐velocity dispersion curves. The goal is to estimate mainly the shear‐wave velocity profile of the investigated site. The model used for the interpretation is 1D, hence results obtained wherever lateral variations are present cannot be considered reliable. In this paper, we study four synthetic models, all with a lateral heterogeneity. When we process the entire corresponding seismograms with traditional f‐k approach, the resulting 1D profiles are representative of the subsurface properties averaged over the whole length of the receivers lines. These results show that classical analysis disregards evidences of sharp lateral velocity changes even when they show up in the raw seismograms. In our research, we implement and test over the same synthetic models, a novel robust automated method to check the appropriateness of 1D model assumption and locate the discontinuities. This new approach is a development of the recent multi‐offset phase analysis with the following further advantages: it does not need previous noise evaluation and more than one shot. Only once the discontinuities are clearly identified, we confidently perform classical f‐k dispersion curve extraction and inversion separately on both sides of the discontinuity. Thus the final results, obtained by putting side by side the 1D profiles, are correct 2D reconstructions of the discontinuous S‐wave distributions obtained without any additional ad‐hoc hypotheses.  相似文献   

Frequency‐dependent multi‐offset phase analysis of surface waves: an example of high‐resolution characterization of a riparian aquifer          下载免费PDF全文

Giulio Vignoli  Isabella Gervasio  Giuseppe Brancatelli  Jacopo Boaga  Bruno Della Vedova  Giorgio Cassiani 《Geophysical Prospecting》2016,64(1):102-111

Multi‐offset phase analysis of seismic surface waves is an established technique for the extraction of dispersion curves with high spatial resolution and, consequently, for the investigation of the subsurface in terms of shear wave velocity distribution. However, field applications are rarely documented in the published literature. In this paper, we discuss an implementation of the multi‐offset phase analysis consisting of the estimation of the Rayleigh wave velocity by means of a moving window with a frequency‐dependent length. This allows maximizing the lateral resolution at high frequencies while warranting stability at the lower frequencies. In this way, we can retrieve the shallow lateral variability with high accuracy and, at the same time, obtain a robust surface‐wave velocity measurement at depth. In this paper, we apply this methodology to a dataset collected for hydrogeophysical purposes and compare the inversion results with those obtained by using refraction seismics and electrical resistivity tomography. The surface‐wave results are in good agreement with those provided by the other methods and demonstrate a superior capability in retrieving both lateral and vertical velocity variations, including inversions. Our results are further corroborated by the lithological information from a borehole drilled on the acquisition line. The availability of multi‐offset phase analysis data also allows disentangling a fairly complex interpretation of the other geophysical results.  相似文献   

Italian accelerometric archive: geological, geophysical and geotechnical investigations at strong-motion stations     

Lucia Luzi  Sara Lovati  Ezio D’Alema  Simone Marzorati  Domenico Di Giacomo  Salomon Hailemikael  Ettore Cardarelli  Michele Cercato  Gerarda Di Filippo  Giuliano Milana  Giuseppe Di Giulio  Mario Rainone  Patrizio Torrese  Patrizio Signanini  Gabriele Scarascia Mugnozza  Stefano Rivellino  Antonella Gorini 《Bulletin of Earthquake Engineering》2010,8(5):1189-1207

Geological, geophysical and geotechnical investigations, for the characterization of the strong-motion recording sites managed by the Italian Civil Protection, have been carried out in the framework of the project “Italian strong-motion database in the period 1972–2004”. The project aimed at creating an updated database of strong-motion data acquired in Italy by different institutions in the time span 1972–2004, and at improving the quality of disseminated data. This article illustrates the state of the recording site characterization before the beginning of the project, explains the criteria adopted to select the sites where geophysical/geotechnical investigation have been performed and describes the results of the promoted field surveys.  相似文献   

Genesis of amethyst geodes in basaltic rocks of the Serra Geral Formation (Ametista do Sul,Rio Grande do Sul,Brazil): a fluid inclusion,REE, oxygen,carbon, and Sr isotope study on basalt,quartz, and calcite   总被引：1，自引：0，他引：1  

H.?Albert?GilgEmail author  Giulio?Morteani  Yuri?Kostitsyn  Christine?Preinfalk  Istvan?Gatter  Adelir?J.?Strieder 《Mineralium Deposita》2003,38(8):1009-1025

In the Ametista do Sul area, Rio Grande do Sul, Brazil, amethyst-bearing geodes are hosted by a ~40- to 50-m-thick subhorizontal high-Ti basaltic lava flow of the Lower Cretaceous Paraná Continental Flood Basalt Province. The typically spherical cap-shaped, sometimes vertically elongated geodes display an outer rim of celadonite followed inwards by agate and colorless and finally amethystine quartz. Calcite formed throughout the whole crystallization sequence, but most commonly as very late euhedral crystals, sometimes with gypsum, in the central cavity. Fluid inclusions in colorless quartz and amethyst are predominantly monophase and contain an aqueous liquid. Two-phase liquid–vapor inclusions are rare. Some with a consistent degree of fill homogenize into the liquid between 95 and 98 °C. Ice-melting temperatures in the absence of a vapor phase between –4 and +4 °C indicate low salinities. Chondrite-normalized REE patterns of calcites are highly variable and show generally no systematic correlation with the paragenetic sequence. The oxygen isotope composition of calcites is very homogeneous (δ¹⁸O_VSMOW=24.9±1.1‰, n=34) indicating crystallization temperatures of less than 100 °C. Carbon isotope values of calcites show a considerable variation ranging from –18.7 to –2.9‰ (VPDB). The ⁸⁷Sr/⁸⁶Sr ratio of calcites varies between 0.706 and 0.708 and is more radiogenic than that of the host basalt (~0.705). The most likely source of silica, calcium, carbon, and minor elements in the infill of the geodes is the highly reactive interstitial glass of the host basalts leached by gas-poor aqueous solutions of meteoric origin ascending from the locally artesian Botucatú aquifer system in the footwall of the volcanic sequence. The genesis of amethyst geodes in basalts at Ametista do Sul, Brazil, is thus considered as a two-stage process with an early magmatic protogeode formation and a late, low temperature infill of the cavity. Editorial handling: A. Cheilletz  相似文献   

The stability of the equilibrium of supermassive and superdense stars     

Giulio Calamai 《Astrophysics and Space Science》1970,6(2):240-257

The second variation of the mass-energy (by constant baryon number) is analysed to inquire into the stability of the equilibrium for a spherical mass under the action of its own gravitation. The equations of general relativity are used. For zero density at the surface, the sphere is stable if (and only if) a solution of a second order equation (Jacobi equation) has only one zero in the interior (at center) of the sphere. The results obtained in this way coincide of course with those obtained by means of the Chandrasekhar-Misner-Zapolsky variational principle, but the solution of the Jacobi equation is more simple and straightforward. In particular, the stability of the several modes are analysed without making any choice of a trial function for the Lagrangian displacement.The method is applied to the GrattonR-polytropic model of supermassive stars.Work done in the Laboratorio Astrofisico, Frascati-Roma, Italy.  相似文献