Polypeptide fromChlamys farreri (PCF), a topical polypeptide isolated fromChlamys farreri, was used in this experiment aimed to investigate the photoprotective effect of PCF against chronic skin damage induced by
ultraviolet A (UVA) and ultraviolet B (UVB) radiation. The chronic ultraviolet-irradiated guinea pig model was established,
and visible changes in the skin including wrinkling, sagging and erythema were observed. Malondialdehyde (MDA) and antioxidant
enzymes including superoxide dismutase (SOD) and glutathione peroxidase (GSH-px) in the dorsal skin were determined using
biochemical methods. The results showed: (1) PCF (5 % and 20%) could greatly protect the dorsal skin of guinea pig against
wrinkling, sagging and erythema induced by UV radiation in a concentration-dependent manner. (2) PCF could reduce MDA formation
in the dorsal skin caused by UV irradiation, while increasing the activities of SOD and GSH-px. (3) The differences among
the PCF groups and UV model group were significant (P<0.05,P<0.01). These results indicated that topical application, of PCF provided broad solar UV spectrum photoprotection; and that
the antioxidant property of PCF might play a role in photoprotection.
Project No. 39970638 supported by the NSFC, and the Science and Technology Bureau of Qingdao (No. 2001-28-50). 相似文献
As well known, the methods of remote sensing and Bowen Ratio for retrieving surface flux are based on energy balance closure; however, in most cases, surface energy observed in experiment is lack of closure. There are two main causes for this: one is from the errors of the observation devices and the differences of their observational scale; the other lies in the effect of horizontal advection on the surface flux measurement. Therefore, it is very important to estimate the effects of horizontal advection quantitatively. Based on the local advection theory and the surface experiment, a model has been proposed for correcting the effect of horizontal advection on surface flux measurement, in which the relationship between the fetch of the measurement and pixel size for remote sensed data was considered. By means of numerical simulations, the sensitivities of the main parameters in the model and the scaling problems of horizontal advection were analyzed. At last, by using the observational data acquired in agricultural field with relatively homogeneous surface, the model was validated.
