Gene Expression Analysis for Exposure to Estrogenic Substances     

Martin Alberti  Ulf Kausch  Stefanie Haindl  Martin Seifert 《洁净——土壤、空气、水》2005,33(1):38-44

Zebrafish (Danio rerio) were exposed with 17β‐estradiol (E2) and nonylphenol (NP) in different concentrations. Gene expression analysis was carried out by two different approaches. First, RT‐PCR experiments were performed for the examination of expression levels of the two marker genes vitellogenin and aromatase. This approach showed a significant increase in the expression of the vitellogenin gene in exposed male fish (500 ng/L 17β‐estradiol and 250 μg/L nonylphenol). This egg yolk protein is usually not synthesized in male vertebrates. A slight decrease of expression of the aromatase gene was observed in exposed female zebrafish. Aromatase is known to catalyze the conversion of androgens to estrogens. Second, DNA microarray experiments were carried out, which allow the simultaneous examination of the expression levels of a great number of marker genes. The microarray experiments resulted in an up‐regulation of vitellogenin up to 850‐fold. In addition, several other genes were identified to be up‐regulated by estrogens, for example the high mobility group box protein ssrp1 (78‐fold) or the chaperonin containing t‐complex polypeptide 1, beta subunit cctb (22‐fold).  相似文献   

The significance of European high mountain lakes in critical load distributions at the EMEP grid scale     

Chris J. Curtis  Max Posch  Pilar Casals-Carrasco  Jordi Catalan  Mike Hughes  Martin Kernan  Marc Ventura 《Aquatic Sciences - Research Across Boundaries》2005,67(3):252-262

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山东莒南后左山恐龙公园早白垩世恐龙足迹化石初步研究   总被引：8，自引：5，他引：8  

李日辉  刘明渭  Lockley Martin R 《地质通报》2005,24(3):277-280

山东省莒南县后左山恐龙公园内保存了数量众多、形态各异的恐龙足迹化石。该足迹化石群产于早白垩世大盛群田家楼组,主要是兽脚类、鸟脚类恐龙的足迹,尤以前者占优质。最大的一个为椭圆形,大小100cm×70cm,可能系鸟脚类恐龙的足迹。鸟脚类足迹大多为椭圆形,长轴一般30～40cm,常呈幻迹保存。最大的兽脚类足迹为三趾型,长49cm,宽35cm,是大型肉食龙类的足迹;最小的一个长8.5cm,宽4.5cm,可能是虚骨龙类的足迹。另外还发现了少量可能是驰龙的足迹,具有2个很长的趾(Ⅲ和Ⅳ趾),趾间角极小,二者几乎平行。鸟脚类恐龙足迹层位分布局限,但密度较大,产出的层面常发育泥裂、波痕,甚至冰晶痕,与泥岩、粉砂质泥岩等层位相关性较强。  相似文献   

Simulation of the development of gypsum maze caves     

Steffen Birk  Rudolf Liedl  Martin Sauter  Georg Teutsch 《Environmental Geology》2005,48(3):296-306

The development of gypsum maze caves under artesian conditions has been simulated. The numerical model simulations show that the evolution of maze caves in this type of setting requires structural preferences such as laterally extended fissure networks in a horizon of the gypsum layer. Without any structural preferences vertical shafts rather than maze caves are predicted to develop. The most important stage for the development of horizontal caves under artesian conditions is found to be the initial karstification period. During this period the structure of the mature conduit system is established. The solutional enlargement of conduits is spatially extended, total dissolution rates are higher than the later ones.  相似文献   

Low-temperature heat capacity of magnesioferrite (MgFe2O4)     

Stephan Klemme  Martin Ahrens 《Physics and Chemistry of Minerals》2005,32(5-6):374-378

The low-temperature heat capacity of magnesioferrite (MgFe₂O₄) was measured between 1.5 K and 300 K, and thermochemical functions were derived from the results. No heat capacity anomaly was observed. From our data, we suggest a standard entropy (298.15 K) for magnesioferrite of 120.8±0.6 J mol⁻¹ K⁻¹, which is about 2.4 J mol⁻¹ K⁻¹ higher than previously reported calorimetric studies; but is in rough agreement with predictions from sets of internally consistent thermodynamic data.  相似文献   

A study of the chemistry of pore fluids and authigenic carbonates in methane seep environments: Kodiak Trench, Hydrate Ridge, Monterey Bay, and Eel River Basin   总被引：3，自引：0，他引：3  

Joris Gieskes  Chris Mahn  Shelley Day  Jonathan B. Martin  Jens Greinert  Tony Rathburn  Brian McAdoo 《Chemical Geology》2005,220(3-4):329-345

Analyses of the chemical and isotopic composition of carbonates rocks recovered from methane seepage areas of the Kodiak Trench, Hydrate Ridge, Monterey Bay Clam Flats, and the Eel River Basin, coupled with the studies of the chemistry of the pore fluids, have shown that these carbonates have grown within the sediment column. Geochemical profiles of pore fluids show that, in deep water seeps (Kodiak Trench—4450 m; Monterey Bay—1000 m; Hydrate Ridge—650 m), δ¹³C (DIC) values are low (isotopically light), whereas in the Eel River area ( 350–500 m), δ¹³C (DIC) values are much higher (isotopically heavier). In all cases, the δ¹³C values indicate that processes of methane oxidation, associated with sulfate reduction, are dominant in the shallow sediments. Data on the isotopic composition of authigenic carbonates found at sites in Kodiak Trench, Eel River Basin South, and Eel River Basin North indicate a variable composition and origin in different geochemical environments. Some of the authigenic carbonates from the study sites show a trend in their δ¹³C values similar to those of the pore fluids obtained in their vicinity, suggesting formation at relatively shallow depths, but others indicate formation at greater sediment depths. The latter usually consist of high magnesium calcite or dolomite, which, from their high values of δ¹³C (up to 23‰;) and δ¹⁸O (up to 7.5‰), suggest formation in the deeper horizons of the sediments, in the zone of methanogenesis. These observations are in agreement with observations by other workers at Hydrate Ridge, in Monterey Bay, and in the Eel River Basin.  相似文献   

Effect of groundwater and sea weathering cycles on the strength of chalk rock from unstable coastal cliffs of NW France     

Anne Duperret  Said Taibi  Rory N. Mortimore  Martin Daigneault 《Engineering Geology》2005,78(3-4):321-343

The aim of this paper is to evaluate the role of groundwater and sea weathering on the strength of the chalk rocks exposed on the coastline of the English Channel in Normandy, NW France. We present a study of the rock strength variations of three representative chalk units (Lewes Chalk, Seaford Chalk and Newhaven Chalk) exposed at various locations on the coastal chalk cliffs. The combination of UCS tests and SEM observations have been used (1) on dry natural chalk samples, (2) on chalk samples at various moisture contents, (3) on dry chalk samples submitted to a 10-day cycle of alternating wetting and drying by distilled water and by sea water. Dry chalk samples show low UCS strength (3.46–4 MPa) indicative of very weak rocks. When chalk samples are submitted to progressive water wetting, they present a decrease of UCS strength and Young's modulus of 40% to 50%. This behaviour begins at low values of water content within the chalk, i.e., for a degree of water saturation ranging between 10% and 17%. When chalk samples are submitted to an artificial weathering cycle with distilled water, a decrease in strength is observed, whereas the Young's modulus increases. SEM observations indicate the occurrence of microcracks and particle aggregates in the sample. When chalk samples are submitted to an artificial weathering with sea water, the decrease of UCS strength and Young's modulus achieves a minimum. SEM observations indicate salt crystals within the chalk. On the coastal cliffs of NW France, weathering processes depend both on chalk lithology, which show a range of sensitivity to weathering and on the location of the chalk in the coastal area. Processes allied to the degree of weathering (e.g., salt crystallisation or fresh water disaggregation) differ in the chalk massif, on the cliff face and on the shore platform.  相似文献   

Neutron powder diffraction study of the orientational order–disorder phase transition in calcite, CaCO3     

Martin T. Dove  Ian P. Swainson  Brian M. Powell  Donald C. Tennant 《Physics and Chemistry of Minerals》2005,32(7):493-503

Neutron powder diffraction studies of calcite on heating towards the orientational order–disorder phase transition show that the phase transition is not a simple analogue of an Ising-like transition, but more similar to a rotational analogue of Lindemann melting. The transition is precipitated by the librational amplitude of the carbonate molecular ions exceeding a critical value rather than a result of a statistical entropy of ‘wrong’ orientations. Using tested interatomic potentials the single-particle orientational potential and nearest-neighbour orientational interactions have been calculated.  相似文献   

The Mesozoic–Cenozoic structural framework of the Bay of Kiel area, western Baltic Sea     

Martin Bak Hansen  Holger Lykke-Andersen  Ali Dehghani  Dirk Gajewski  Christian Hübscher  Morten Olesen  Klaus Reicherter 《International Journal of Earth Sciences》2005,94(5-6):1070-1082

A dense grid of multichannel high-resolution seismic sections from the Bay of Kiel in the western Baltic Sea has been interpreted in order to reveal the Mesozoic and Cenozoic geological evolution of the northern part of the North German Basin. The overall geological evolution of the study area can be separated into four distinct periods. During the Triassic and the Early Jurassic, E–W extension and the deposition of clastic sediments initiated the movement of the underlying Zechstein evaporites. The deposition ceased during the Middle Jurassic, when the entire area was uplifted as a result of the Mid North Sea Doming. The uplift resulted in a pronounced erosion of Upper Triassic and Lower Jurassic strata. This event is marked by a clear angular unconformity on all the seismic sections. The region remained an area of non-deposition until the end of the Early Cretaceous, when the sedimentation resumed in the area. Throughout the Late Cretaceous the sedimentation took place under tectonic quiescence. Reactivated salt movement is observed at the Cretaceous Cenozoic transition as a result of the change from an extensional to compressional regional stress field. The vertical salt movement influenced the Cenozoic sedimentation and resulted in thin-skinned faulting.  相似文献   

Late Neogene low-angle thrusting on the northwestern margin of the South Carpathians (Poiana Rusca, West Romania)     

Martin S. Oczlon  Dan Onescu 《Tectonophysics》2005,410(1-4):367-377

Mineral exploration drillholes and geoelectric prospecting provide for the first time evidence for thrusting of the South Carpathian Paleozoic basement over northerly adjacent Middle Miocene sediments. Investigations were carried out in two locations, 30 km apart, along the northern margin of the Poiana Rusca Mountains, Romania, southwestern Carpathians. Drill holes in both locations encountered weakly consolidated Middle Miocene clay, sand, and fine gravel below Paleozoic low-grade metamorphic rocks. Intersections from various drill holes demonstrate the presence of low-angle thrusting. Kinematic indicators are so far lacking, but with a thrust direction oriented roughly normal to strike of the Poiana Rusca Mountains, minimum displacement is 1–1.4 km in northwestern or northern direction, respectively. Thrusting occurred most likely during the Late Miocene–Pliocene, whereafter Quaternary regional uplift dissected the thrust plane. In the tectonic framework of Neogene dextral translation of the Tisza–Dacia Block against the southerly adjacent Moesian Platform, transtension appears responsible for Middle Miocene basin formation along the northern margin of the Poiana Rusca region. Proceeding collision of the Tisza–Dacia Block with the East European Craton introduced stronger impingement of the Tisza–Dacia Block against the Moesian Platform, leading to a Late Miocene–Pliocene transpressional regime, in which the northern Poiana Rusca basement was thrust over its adjacent Middle Miocene sediments.  相似文献