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The refractory meteorite inclusions known as CAIs (calcium-aluminum rich inclusions) display melted rims that were produced by thermal events of only a few seconds duration. We show that gas dynamic deceleration in a temporary atmosphere around an accreting parent body, produced by gas release during accretion, could provide a regime of sufficiently high gas density and small scale height to achieve partial melting of the CAIs. In addition, the presence of dust in the atmosphere would increase the gradient of pressure with height (i.e., effectively reduce the scale height), lower the rate of blowoff (thus keeping more gas around the body), as well as allow dust particles to become trapped in the partially melted material as is observed in some cases. Thus, CAIs may be regarded as probes of a primitive atmosphere by virtue of the thermal and mineralogical alteration that occurred upon their passage through the atmosphere. 相似文献
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GSTA is a major glutathione S-transferase gene responsible for 4-hydroxynonenal conjugation in largemouth bass liver 总被引:2,自引:0,他引:2
We have previously shown that largemouth bass (Micropterus salmoides) has a remarkable ability to conjugate 4-hydroxy-2-nonenal (4HNE), a mutagenic and cytotoxic alpha,beta-unsaturated aldehyde produced during the peroxidation of lipids. In addition, we have isolated a glutathione S-transferase cDNA (bass GSTA) that encodes a recombinant protein which is highly active in 4HNE conjugation and structurally similar to plaice (Pleuronectes platessa) GSTA. In the present study, HPLC-GST subunit analysis revealed the presence of at least two major GST isoforms in bass liver, with one peak constituting 80% of the total bass liver GST protein. Liquid chromatography mass spectrometry (LC-MS) and electrospray ionization analysis of the major bass GST subunit yielded a molecular weight of 26,396 kDa. Endo-proteinase Lys-C digestion and Edman degradation protein sequencing of this GST peak demonstrated that this protein was encoded by bass GSTA. Analysis of genomic DNA fragments isolated by nested PCR indicated the presence of a GST gene cluster in bass liver that contained GSTA, and was similar to a GST gene cluster characterized by Leaver et al., in plaice. Collectively, our data indicates the presence of a major GST in bass liver involved in the protection against oxidative stress. This GST is part of a gene cluster that may be conserved in certain freshwater and marine fish. 相似文献
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Concern has been raised that the increased use of pesticides in intensive aquaculture practices may cause adverse sublethal effects to non-target aquatic species. Azamethiphos is an organophosphate (OP) pesticide used to combat sea lice infestations in farmed salmonids. Here, the sublethal impact on the blue mussel, Mytilus edulis, of short term exposure to azamethiphos was determined. The testing regime included biomarkers of exposure (acetylcholinesterase activity), cytotoxicity (neutral red retention), immune function (phagocytic index) and physiological condition (feeding rate). The distribution and sensitivity of M. edulis acetylcholinesterase to inhibition by azamethiphos was first determined, yielding IC(50) values of 0.736 and 1.30 mg l(-1) for gill and haemolymph, respectively. Exposure of mussels to 0.1 mg l(-1) azamethiphos for periods of up to 24h caused a significant reduction in acetylcholinesterase activity in both the haemolymph (P<0.0002) and the gill (P<0.002), alteration in cell viability (P<0.02) and decrease in phagocytic index (P<0.03). The feeding rate remained unaffected. The results support the hypothesis that, in addition to its neurotoxic effects, azamethiphos can modulate haemocyte function and immune defence in M. edulis at environmentally relevant concentrations after only a few hours. 相似文献
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夏威夷群岛的向外幅射海岭沿该岛火山的主断裂带演化。希洛海岭与冒纳凯阿火山呈经向由夏威夷向东伸延 ,被认为是夏威夷火山的一部分。冒纳凯阿火山超覆于较古老的科哈拉火山 ,以致于科哈拉的重力高接近于冒纳凯阿边缘 ,表明科哈拉火山筑积物远离冒纳凯阿的侧翼下方伸延。据推测 ,希洛海岭起源于科哈拉在南部断裂带 ,其后 ,冒纳凯阿演化使其增大。笔者乘“ThomasG.Thompson”号调查船调查古老的科哈拉火山筑积物残余 ,此处可能是冒纳凯阿年轻熔岩未覆盖部分。将希洛海岭视为科哈拉的一部分能够说明约1100m的阶地的生成… 相似文献
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