Protective effect of topically applied polypeptide from Chlamys farreri against ultraviolet radiation-induced chronic skin damage in guinea pig     

Chi Mingliang  Cao Pengli  Yu Guoying  Zhu Li  Wang Yuejun  Wang Chunbo 《中国海洋湖沼学报》2003,21(4):319-323

Polypeptide fromChlamys farreri (PCF), a topical polypeptide isolated fromChlamys farreri, was used in this experiment aimed to investigate the photoprotective effect of PCF against chronic skin damage induced by ultraviolet A (UVA) and ultraviolet B (UVB) radiation. The chronic ultraviolet-irradiated guinea pig model was established, and visible changes in the skin including wrinkling, sagging and erythema were observed. Malondialdehyde (MDA) and antioxidant enzymes including superoxide dismutase (SOD) and glutathione peroxidase (GSH-px) in the dorsal skin were determined using biochemical methods. The results showed: (1) PCF (5 % and 20%) could greatly protect the dorsal skin of guinea pig against wrinkling, sagging and erythema induced by UV radiation in a concentration-dependent manner. (2) PCF could reduce MDA formation in the dorsal skin caused by UV irradiation, while increasing the activities of SOD and GSH-px. (3) The differences among the PCF groups and UV model group were significant (P<0.05,P<0.01). These results indicated that topical application, of PCF provided broad solar UV spectrum photoprotection; and that the antioxidant property of PCF might play a role in photoprotection. Project No. 39970638 supported by the NSFC, and the Science and Technology Bureau of Qingdao (No. 2001-28-50).  相似文献   

    

A. S. Belyakov  V. S. Lavrov  A. V. Nikolaev  L. L. Khudzinskii 《Doklady Earth Sciences》2006,407(2):258

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胶东“玲珑-焦家式”金矿资源潜力与找矿   总被引：1，自引：1，他引：0  

李士先  王建收 《山东国土资源》2006,22(12):36-41

“玲珑焦家式”金矿的成岩成矿,从新太古代至中生代存在着继承性的成因关系,成矿具有长期性、多源性特点,但中生代燕山早期岩浆活动是主导成矿因素。区域化探成果显示胶东金矿直接矿源岩———郭家岭花岗岩金的丰度比原始矿源岩———早前寒武纪变质沉积岩系及侵入岩系金的丰度低1/2。郭家岭花岗岩面积在2 km2以上岩体定量估计金亏损总量与胶东金矿总量预测的资源量相当,从一个侧面展现了胶东金矿资源的潜力。望儿山金矿的找矿实践展示,焦家式金矿在1 000 m以下尚有巨大潜力,整个胶东金矿产区在3 000 m以上的资源潜力应在5000 t以上。  相似文献   

差分法周跳探测与修复方法改进     

郑作亚  程宗颐  黄珹 《中国科学院上海天文台年刊》2004,(1)

在目前常用的周跳探测与修复方法基础上 ,提出了首先将观测资料按照观测历元不连续分成若干小弧段 ,然后利用差分法进行周跳探测 ,根据差分后周跳放大的特性判断周跳和野值 ,并确定其位置利用宽带组合和电离层组合的方法解算周跳大小。通过实例验证了其有效性。  相似文献   

Application of Grain Size Analysis to Study Sedimentary Environment of Sand Dune in the Vicinity of Tumen River     

Feng Ma  Li Liu  Lin Cao 《东北亚地学研究》2003,(1)

The dunes in estuary of Tumen River in China lie to the area between the Jiushaping and Fangchuan in the left bank of Tumen River (Fig.1). The dis-tance is about 15～20 km between the dunes and the coast. It ranges from China to D. P. R. Korea and Russia. The range of the height of dunes is about 15～20 m and the width is 100～200 m. By the re-connaissance, we protracted 9 section planes of the dunes and collected 40 sand samples of the dunes, and identified the sedimentary environment …  相似文献   

Quantifying hydrogen‐deuterium exchange of meteoritic dicarboxylic acids during aqueous extraction     

Megan FULLER  Yongsong HUANG 《Meteoritics & planetary science》2003,38(3):357-363

Abstract— Hydrogen isotope ratios of organic compounds in carbonaceous chondrites provide critical information about their origins and evolutionary history. However, because many of these compounds are obtained by aqueous extraction, the degree of hydrogen‐deuterium (H/D) exchange that occurs during the process needs to be quantitatively evaluated. This study uses compound‐specific hydrogen isotopic analysis to quantify the H/D exchange during aqueous extraction. Three common meteoritic dicarboxylic acids (succinic, glutaric, and 2‐methyl glutaric acids) were refluxed under conditions simulating the extraction process. Changes in δD values of the dicarboxylic acids were measured following the reflux experiments. A pseudo‐first order rate law was used to model the H/D exchange rates which were then used to calculate the isotope exchange resulting from aqueous extraction. The degree of H/D exchange varies as a result of differences in molecular structure, the alkalinity of the extraction solution and presence/absence of meteorite powder. However, our model indicates that succinic, glutaric, and 2‐methyl glutaric acids with a δD of 1800%***_o would experience isotope changes of 38_o, 10_o, and 6_o, respectively during the extraction process. Therefore, the overall change in δD values of the dicarboxylic acids during the aqueous extraction process is negligible. We also demonstrate that H/D exchange occurs on the chiral α‐carbon in 2‐methyl glutaric acid. The results suggest that the racemic mixture of 2‐methyl glutaric acid in the Tagish Lake meteorite could result from post‐synthesis aqueous alteration. The approach employed in this study can also be used to quantify H/D exchange for other important meteoritic compounds such as amino acids.  相似文献   

Geological environment conflicts of Kunming Basin and its urban sustainable development     

Jianhua FAN Bingfei SHI 《东北亚地学研究》2006,9(2):217-219

Kunming Basin locates middle of Yunnan altiplano and has a particularity in geography,topographic and geological environment.With the urban dilation quickly,add the reason of the unreasonable city layout,conflicts between environment and urban resources consumption become shrill increasingly.It is human being activities that lead to vulnerability and depravation of geological environment in local.Take a few examples on geological environment to expatiate relationship between urban construction and geological environment carrying capacity,and find a way how to make a better plan for urban sustainable development to achieve new balance between man and nature in local.  相似文献   

超基性岩中含铜、钴块状硫化物矿床——德尔尼铜矿成因新认识   总被引：1，自引：0，他引：1  

章午生  陈杰 《青海国土经略》1996,(1)

长期以来对德尔尼铜矿的成因存在着不同认识。从矿石组成和结构、构造来看,应属典型的块状硫化物矿石,矿床亦应属于含铜黄铁矿型矿床。但从其地质产状来看又与一般的黄铁矿型矿床大不相同,与一般的岩浆熔离铜镍硫化物矿床也有较多差异。这就是本矿床类型独特之处。近年来通过工作又取得一些新资料,特别是超基性岩和矿石的同位素年龄数据。本文在综合新老资料基础上,提出新看法,认为该矿床形成于上地幔,再就位于地壳浅部。其成因类型暂定为:“深部熔离—构造侵位矿床”。鉴于本矿床与一般块状硫化物矿床相比有其独特性,建议命名为“德尔尼型”。  相似文献   

南海北缘北东东向构造活动性研究     

任镇寰  任奔滔  罗振暖  陈益明  钟贻军 《大地测量与地球动力学》1996,(2)

从地形地貌特征、重磁地球物理场、深部构造与断裂构造以及地震活动、震源机制等多方面论述北东东向构造是南海北缘的主要活动构造。对于长期以来认为新华夏系北东向构造是该区主要活动构造的观点来说，这是一种新的学术思想。  相似文献   

有限元法与伪谱法混合求解弹性波动方程   总被引：6，自引：0，他引：6  

马德堂  朱光明 《地球科学与环境学报》2004,26(1):61-64

在地震波场数值模拟中,有限差分法、有限元法和伪谱法都是常用的基本方法,但它们各有不同的适应性和优缺点,如有限差分法、有限元法都存在减弱网格频散和提高计算效率的矛盾,而伪谱法的网格频散小且计算效率高.有限差分法和伪谱法在处理地表结构复杂或地表剧烈起伏以及地下结构复杂的情况时存在较大的难度,而有限元法可较为理想地拟合起伏地表和任意弯曲界面,且可方便地处理自由边界条件和界面边界条件.尝试将有限元法和伪谱法相结合,形成地震波场数值模拟的一种混合方法,利用二者的优点,克服二者的缺点,达到既减弱网格频散又提高计算精度和效率的目的.并采用所谓的‘过度区域‘技术解决两种不同算法的衔接问题.模拟实例表明,给出的混合模拟方法不失为弹性波场数值模拟的一种有效方法.  相似文献