Joint FAO/WHO/IOC activities to provide scientific advice on marine biotoxins (research report)   总被引：1，自引：0，他引：1  

Toyofuku H 《Marine pollution bulletin》2006,52(12):1735-1745

The Joint FAO/WHO/IOC ad hoc Expert Consultation on Biotoxins in Molluscan Bivalves performed risk assessments for a number of biotoxins present in bivalve molluscs. For performing risk assessments, the Expert Consultation categorized the biotoxins into eight distinct groups based on chemical structure. The Expert Consultation established LOAELs for the azaspiracid (AZA), okadaic acid (OA), saxitoxin (STX), and domoic acid (DA) toxin groups. The derived provisional acute RfDs for the AZA, OA, STX, and DA toxin groups were 0.04 μg/kg bw, 0.33 μg/kg bw, 0.7 μg/kg bw, and 100 μg/kg bw, respectively. For the yessotoxin (YTX) group, a NOAEL was established, based on animal studies. Applying a safety factor of 100, a provisional acute RfD of 50 μg/kg bw was suggested for the YTX group. The Expert Consultation considered that the database for cyclic imines, brevetoxins, and pectenotoxins was insufficient to establish provisional acute RfDs for these three toxin groups.  相似文献   

Comparison of carbon cycle between the western Pacific subarctic and subtropical time-series stations: highlights of the K2S1 project     

Makio C. Honda  Masahide Wakita  Kazuhiko Matsumoto  Tetsuichi Fujiki  Eko Siswanto  Kosei Sasaoka  Hajime Kawakami  Yoshihisa Mino  Chiho Sukigara  Minoru Kitamura  Yoshikazu Sasai  Sherwood L. Smith  Taketo Hashioka  Chisato Yoshikawa  Katsunori Kimoto  Shuichi Watanabe  Toru Kobari  Toshi Nagata  Koji Hamasaki  Ryo Kaneko  Mario Uchimiya  Hideki Fukuda  Osamu Abe  Toshiro Saino 《Journal of Oceanography》2017,73(5):647-667

A comparative study of ecosystems and biogeochemistry at time-series stations in the subarctic gyre (K2) and subtropical region (S1) of the western North Pacific Ocean (K2S1 project) was conducted between 2010 and 2013 to collect essential data about the ecosystem and biological pump in each area and to provide a baseline of information for predicting changes in biologically mediated material cycles in the future. From seasonal chemical and biological observations, general oceanographic settings were verified and annual carbon budgets at both stations were determined. Annual mean of phytoplankton biomass and primary productivity at the oligotrophic station S1 were comparable to that at the eutrophic station K2. Based on chemical/physical observations and numerical simulations, the likely “missing nutrient source” was suggested to include regeneration, meso-scale eddy driven upwelling, meteorological events, and eolian inputs in addition to winter vertical mixing. Time-series observation of carbonate chemistry revealed that ocean acidification (OA) was ongoing at both stations, and that the rate of OA was faster at S1 than at K2 although OA at K2 is more critical for calcifying organisms.  相似文献