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31.
The Faroe Islands in the North Atlantic Ocean are susceptible to flow-type landslides in coarse-grained highly organic colluvium. Following several hazardous debris avalanche events, research work has been initiated to quantify landslide risk. A central task in this work is to predict landslide runout behavior. From numerical simulation of four debris avalanches, this study provides a first screening of which rheology and appertaining input parameters best predict runout behavior of debris avalanches in the Faroe Islands. Three rheologies (frictional, Voellmy, and Bingham) are selected and used for individual back analysis of the events in the numerical models BING and DAN3D. A best fit rheology is selected from comparing predicted and observed landslide runout behavior. General back analysis to identify the optimal input parameters for the chosen rheology is performed by cross validation, where each debris avalanche is modeled with input parameters from the three other events. Optimal input parameters are found from the model run producing the most accurate runout length and velocity. The Bingham is selected as the best fit rheology, a result differing from similar studies of coarse-grained landslides. A reason for why particularly the frictional rheology proves unsuitable is its tendency to produce too long runout lengths of the low-weight runout material, a result showing important limitations for using the frictional rheology in DAN3D. Optimal Bingham input parameters are τ y ?=?980 Pa and μ b ?=?117 Pa/s. However, future studies performed in 2D models are needed for precise parameterization before results can be used for landslide risk assessment.  相似文献   
32.
Previous studies have shown that aryl hydrocarbon receptor (AhR) agonists possess anti-estrogenic activities and several mechanisms have been proposed to explain the interactions between AhR and estrogen receptor (ER) signalling pathways. In the present study, we show that 3,3'4,4'5-pentachlorobiphenyl (PCB126 - a dioxin-like AhR agonist) produced estrogenic responses in the absence of ER agonist, in fish in vitro system. We exposed salmon primary hepatocytes to PCB126 (1, 10 and 50 pM) and the ER agonist nonylphenol (NP; 5 and 10 microM) singly and also in combination. Vitellogenin (Vtg) and zona radiata proteins (Zr-proteins) levels were analysed by semi-quantitative ELISA. We observed that the protein levels of Vtg and Zr-proteins were significantly induced in a concentration-specific manner in cells treated with PCB126 and NP, singly or in combination. In general, these results show a novel aspect of dioxin-like PCB effect not previously demonstrated in fish system.  相似文献   
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