Protective effect of topically applied polypeptide from Chlamys farreri against ultraviolet radiation-induced chronic skin damage in guinea pig     

Chi Mingliang  Cao Pengli  Yu Guoying  Zhu Li  Wang Yuejun  Wang Chunbo 《中国海洋湖沼学报》2003,21(4):319-323

Polypeptide fromChlamys farreri (PCF), a topical polypeptide isolated fromChlamys farreri, was used in this experiment aimed to investigate the photoprotective effect of PCF against chronic skin damage induced by ultraviolet A (UVA) and ultraviolet B (UVB) radiation. The chronic ultraviolet-irradiated guinea pig model was established, and visible changes in the skin including wrinkling, sagging and erythema were observed. Malondialdehyde (MDA) and antioxidant enzymes including superoxide dismutase (SOD) and glutathione peroxidase (GSH-px) in the dorsal skin were determined using biochemical methods. The results showed: (1) PCF (5 % and 20%) could greatly protect the dorsal skin of guinea pig against wrinkling, sagging and erythema induced by UV radiation in a concentration-dependent manner. (2) PCF could reduce MDA formation in the dorsal skin caused by UV irradiation, while increasing the activities of SOD and GSH-px. (3) The differences among the PCF groups and UV model group were significant (P<0.05,P<0.01). These results indicated that topical application, of PCF provided broad solar UV spectrum photoprotection; and that the antioxidant property of PCF might play a role in photoprotection. Project No. 39970638 supported by the NSFC, and the Science and Technology Bureau of Qingdao (No. 2001-28-50).  相似文献   

蜕壳素对凡纳滨对虾生长及表观消化率的影响     

刘立鹤  郑石轩  徐焕新  郑献昌 《广东海洋大学学报》2003,23(4):30-36

研究了外源性蜕皮激素对凡纳滨对虾生长和表观消化率的影响 ,实验时在基础饲料中分别添加 0 .1%、0 .2 %、0 .4 %的两种市售蜕壳素产品 ,制成 6种外源性脱壳素配合饲料 ,不添加的基础饲料作为对照组 ,试验在 2 6 0L玻璃钢循环水养殖系统中 ,每个剂量组设 3个重复 ,8周生长试验结果表明 :市售蜕壳素产品能有效地促进对虾生长 ,试验结束时 ,试验组虾体增重分别较对照组增加 16 .8%、7.5 2 %、5 .9%、11.4 %、2 9.0 7%、16 .5 3% ,但是凡纳滨对虾对饲料粗蛋白的表观消化率没有明显地提高 ,凡纳滨对虾对脂肪的表观消化率较低。推算凡纳滨对虾饲料中最佳蜕皮酮添加量为 6 0mg/kg。  相似文献   

Bond rolling resistance and its effect on yielding of bonded granulates by DEM analyses     

M. J. Jiang  H. S. Yu  D. Harris 《国际地质力学数值与分析法杂志》2006,30(8):723-761

A discrete element modelling of bonded granulates and investigation on the bond effect on their behaviour are very important to geomechanics. This paper presents a two‐dimensional (2‐D) discrete element theory for bonded granulates with bond rolling resistance and provides a numerical investigation into the effect of bond rolling resistance on the yielding of bonded granulates. The model consists of mechanical contact models and equations governing the motion of bonded particles. The key point of the theory is that the assumption in the original bond contact model previously proposed by the authors (55th CSCE‐ASCE Conference, Hamilton, Ont., Canada, 2002; 313–320; J. Eng. Mech. (ASCE) 2005; 131 (11):1209–1213) that bonded particles are in contact at discrete points, is here replaced by a more reliable assumption that bonded particles are in contact over a width. By making the idealization that the bond contact width is continuously distributed with the normal/tangential basic elements (BE) (each BE is composed of spring, dashpot, bond, slider or divider), we establish a bond rolling contact model together with bond normal/tangential contact models, and also relate the governing equations to local equilibrium. Only one physical parameter β needs to be introduced in the theory in comparison to the original bond discrete element model. The model has been implemented into a 2‐D distinct element method code, NS2D. Using the NS2D, a total of 86 1‐D, constant stress ratio, and biaxial compressions tests have been carried out on the bonded granular samples of different densities, bonding strengths and rolling resistances. The numerical results show that: (i) the new theory predicts a larger internal friction angle, a larger yielding stress, more brittle behaviour and larger final broken contact ratio than the original bond model; (ii) the yielding stress increases nonlinearly with the increasing value of β, and (iii) the first‐yield curve (initiation of bond breakage), which define a zone of none bond breakage and which shape and size are affected by the material density, is amplified by the bond rolling resistance in analogous to that predicted by the original bond model. Copyright © 2006 John Wiley & Sons, Ltd.  相似文献   

测定天琴RR变星金属丰度的方法     

吴潮  胡景耀  赵永恒 《天文学进展》2006,24(4):308-318

银晕中天琴RR变星金属丰度的测定对于研究银河系晕的形成和演化具有重要的意义．在当前的技术条件下,高分辨光谱的方法难以测量银晕中较暗的天琴RR变星的金属丰度．高分辨光谱测定金属丰度的方法对恒星大气模型的依赖性较高,而恒星脉动引起的复杂大气状况对于建立正确的大气模型本身就是挑战．△S光谱方法、Caby测光方法和光变曲线的参数方法则弥补了高分辨光谱方法的不足,将能测量更远距离上的天琴RR变星的金属丰度．着重介绍了这3种方法发展的历史、具体的观测流程以及需要注意的问题。通过比较这3种方法的优劣,为实际观测时方法的选用提供借鉴。  相似文献   

酶解法提取鱼油的工艺参数优化   总被引：1，自引：0，他引：1  

洪鹏志刘书成  章超桦吉宏武 《广东海洋大学学报》2006,26(3):56-60

利用蛋白酶酶解法从黄鳍金枪鱼（Thunnus albacares）加工的下脚料——鱼头中提取鱼油。以鱼油提取率和感官特征为指标，通过正交优化实验设计，获得了胰蛋白酶提取鱼油的最佳酶解工艺参数：酶解温度45℃，酶添加量1．5％．料液质量比1：1，酶解时间4h，酶解pH8。在该条件下．鱼油的提取率为4．34％，理化指标除过氧化值外均达到SC／T3502-2000的粗鱼油二级标准。多不饱和脂肪酸总含量高达38．47％,其中DHA和EPA的含量分别为23．63％和4．84％。  相似文献   

    

A. S. Belyakov  V. S. Lavrov  A. V. Nikolaev  L. L. Khudzinskii 《Doklady Earth Sciences》2006,407(2):258

  相似文献   

胶东“玲珑-焦家式”金矿资源潜力与找矿   总被引：1，自引：1，他引：0  

李士先  王建收 《山东国土资源》2006,22(12):36-41

“玲珑焦家式”金矿的成岩成矿,从新太古代至中生代存在着继承性的成因关系,成矿具有长期性、多源性特点,但中生代燕山早期岩浆活动是主导成矿因素。区域化探成果显示胶东金矿直接矿源岩———郭家岭花岗岩金的丰度比原始矿源岩———早前寒武纪变质沉积岩系及侵入岩系金的丰度低1/2。郭家岭花岗岩面积在2 km2以上岩体定量估计金亏损总量与胶东金矿总量预测的资源量相当,从一个侧面展现了胶东金矿资源的潜力。望儿山金矿的找矿实践展示,焦家式金矿在1 000 m以下尚有巨大潜力,整个胶东金矿产区在3 000 m以上的资源潜力应在5000 t以上。  相似文献   

我国个人所得税制度完善的法律思考     

刘升 《广东海洋大学学报》2006,26(2):44-46

个人所得税是与每个人联系都很紧密的税种,它的完善与否,直接体现了我国法制建设的完善程度及居民素质的高低。但现行税制由于内外原因,存在各种缺陷。因此有必要在理论中找到对策,并在实践中寻求答案逐步完善个人所得税制度。  相似文献   

应用ATA的对数周期馈源方案于FAST的可能性探讨     

吴盛殷  熊继衮  吕善伟  张江林  徐祥  南仁东  金乘进 《天文学进展》2004,22(2):179-187

介绍应用于美国凤凰计划的Allen望远镜阵(ATA)的对数周期馈源(LPA)概况，初步给出此种馈源的基本参数及性能，仿真估算了其驻波比和方向图，并结合正在进行中的我国500m孔径球面射电望远镜(FAST)计划，探讨了应用这种宽带馈源的可能性及其限制。  相似文献   

Parameters of the intense X-ray and gamma-ray radiation from the solar flare of May 20, 2002, as observed from the Coronas-F spacecraft     

A. V. Bogomolov  A. P. Ignat’ev  K. Kudela  S. N. Kuznetsov  Yu. I. Logachev  O. V. Morozov  I. N. Myagkova  S. N. Oparin  A. A. Pertsov  S. I. Svertilov  B. Yu. Yushkov 《Astronomy Letters》2003,29(3):199-204

We consider temporal, spectral, and polarization parameters of the hard X-ray and gamma-ray radiation observed during the solar flare of May 20, 2002, in the course of experiments with the SONG and SPR-N instruments onboard the Coronas-F spacecraft. This flare is one of the most intense gamma-ray events among all of the bursts of solar hard electromagnetic radiation detected since the beginning of the Coronas-F operation (since July 31, 2001) and one of the few gamma-ray events observed during solar cycle 23. A simultaneous analysis of the Coronas-F and GOES data on solar thermal X-ray radiation suggests that, apart from heating due to currents of matter in the the flare region, impulsive heating due to the injection of energetic electrons took place during the near-limb flare S21E65 of May 20, 2002. These electrons produced intense hard X-ray and gamma-ray radiation. The spectrum of this radiation extends up to energies ≥7 MeV. Intense gamma-ray lines are virtually unobservable against the background of the nonthermal continuum. The polarization of the hard X-ray (20–100 keV) radiation was estimated to be ≤15–20%. No significant increase in the flux of energetic protons from the flare under consideration was found. At the same time, according to ACE data, the fluxes of energetic electrons in interplanetary space increased shortly (～25 min) after the flare.  相似文献