Lysosomal injury and MFO activity in the liver of flounder (Platichthys flesus L.) in relation to histopathology of hepatic degeneration and carcinogenesis     

Angela Khler  Hans Jürgen Pluta 《Marine environmental research》1995,39(1-4)

Flounder (Platichthys flesus L.), 18–48 cm total length were sampled in the mouth of the Elbe River during a 3-year interdisciplinary project ‘Fish Diseases in the Wadden Sea’. Lysosomal changes (lysosomal membrane stability) and the activity of biotransforming enzymes (MFOs/EROD) were measured parallel to investigations of ultrastructural changes in liver cells, tissue pathologies and macroscopically visible changes. The aim of the study was to investigate if these cyto- and biochemical parameters were able to reflect contaminant induced biological effects. Interlinking of the results of the MFO activity to the pathological alterations observed at the electron- and light-microscopic levels as well as during macroscopic inspection of identical individuals evidenced that the activity of the biotransformation enzymes (EROD) was not induced in healthy livers, increased considerably with the onset of liver changes and dropped again in those livers with degenerative, preneoplastic and neoplastic lesions. In contrast, concurrent studies of lysosomal membrane stability measured in parallel showed a decrease with the onset and progression of liver lesions from reversible to irreversible, neoplastic change.  相似文献   

Variability of organic δC and C/N in the Mersey Estuary, U.K. and its implications for sea-level reconstruction studies     

Graham P. Wilson  Angela L. Lamb  Melanie J. Leng  Silvia Gonzalez  David Huddart 《Estuarine, Coastal and Shelf Science》2005,64(4):685-698

Microfossil analysis (e.g. diatoms, foraminifera and pollen) represents the cornerstone of Holocene relative sea-level (RSL) reconstruction because their distribution in the contemporary inter-tidal zone is principally controlled by ground elevation within the tidal frame. A combination of poor microfossil preservation and a limited range in the sediment record may severely restrict the accuracy of resulting RSL reconstructions. Organic δ¹³C and C/N analysis of inter-tidal sediments have shown some potential as coastal palaeoenvironmental proxies. Here we assess their viability for reconstructing RSL change by examining patterns of organic δ¹³C and C/N values in a modern estuarine environment. δ¹³C and C/N analysis of bulk organic inter-tidal sediments and vegetation, as well as suspended and bedload organic sediments of the Mersey Estuary, U.K., demonstrate that the two main sources of organic carbon to surface saltmarsh sediments (terrestrial vegetation and tidal-derived particulate organic matter) have distinctive δ¹³C and C/N signatures. The resulting relationship between ground elevation within the tidal frame and surface sediment δ¹³C and C/N is unaffected by decompositional changes. The potential of this technique for RSL reconstruction is demonstrated by the analysis of part of an early Holocene sediment core from the Mersey Estuary. Organic δ¹³C and C/N analysis is less time consuming than microfossil analysis and is likely to provide continuous records of RSL change.  相似文献   

Carbon cycling through the pelagic foodweb in the northern Humboldt Current off Chile (23{degrees}S)     

Gonzalez  H.E.; Giesecke  R.; Vargas  C.A.; Pavez  M.; Iriarte  J.; Santibanez  P.; Castro  L.; Escribano  R.; Pages  F. 《ICES Journal of Marine Science》2004,61(4):572-584

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Diel vertical behaviour, predator-prey relationships, and occupation of space by jack mackerel (Trachurus murphyi) off Chile   总被引：3，自引：0，他引：3  

Bertrand  Arnaud; Barbieri  Maria Angela; Cordova  Jose; Hernandez  Carola; Gomez  Fabian; Leiva  Francisco 《ICES Journal of Marine Science》2004,61(7):1105-1112

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A seasonal survey of the sterol composition of the cockle cerastoderma edule: A comparison of polluted and non-polluted environments     

James A Ballantine  Angela Lavis  Robert J Morris 《Marine environmental research》1983,9(2):111-122

The sterol composition of a cockle population from an unpolluted environment in South Wales was monitored by monthly sampling over a 12-month period. In spite of the likely variation in dietary sterols during this period, the component sterols of the cockles showed no significant seasonal variation, indicating that the cockle was able to exhibit a high degree of control over the composition of its functional sterols.Dramatic differences were observed in the sterol compositions of a nearby cockle population from a highly polluted environment, near a sewage outfall; only three out of the ten sterols present were common to the unpolluted cockles. Forty-five per cent of the sterols from the ‘polluted’ samples contained fully reduced systems and included three new alkylated C-29, C-30 and C-31 stanols. It is considered possible that these structural changes may affect the stereochemistry of the functional sterols and hence alter the permeability of the animal's membranes. This may reflect a biochemical response to the polluted environment.  相似文献   

Multifrequency behayiour of the dwarf nova SS Cygni     

F. Giovannelli  I. Gonzalez Martinez-Pais  S. Gaudenzi  R. Lombardi  C. Rossi  R. U. Claudi 《Astrophysics and Space Science》1990,169(1-2):125-132

Several years of coordinated multifrequency observations of the dwarf nova SS Cygni have been performed in order to study the accretion behaviour of this system in particular, and in general to clarify this crucial problem for the cataclysmic variables.From IUE measurements, together with those from optical and IR ground based telescopes, we have found orbital modulations in the continuum and in the equivalent widths of the emission lines. During quiescent phases the behaviour of SS Cygni are dependent on the type of the preceding outburst (long-type or short-type).In this paper we will discuss the physical implications one can derive from these results.Paper presented at the 11th European Regional Astronomical Meetings of the IAU on New Windows to the Universe, held 3–8 July, 1989, Tenerife, Canary Islands, Spain.Based on the observations performed with IUE (VILSPA) satellite, and with the telescopes of the Loiano and Roque de los Muchachos Observatories.  相似文献   

Asking the right questions: environmental conflict in the case of Azerbaijan     

Shannon O'Lear  Angela Gray 《Area》2006,38(4):390-401

This paper contributes an empirical test of key themes of the literature on natural resource conflict. Survey and interview data from an ongoing project in Azerbaijan provide insights into an unexpected lack of conflict in Azerbaijan related to the environment, resources and energy despite the predictions of resource conflict literature. We contend that questions about public perceptions about the environment and other daily concerns are critical if we are to understand who is likely (or unlikely) to be involved in conflict and why. The data presented in this paper demonstrate that Azerbaijani citizens rank environmental and resource issues among their immediate concerns and their top concerns for the country. However, compared to other day-to-day concerns such as the Nagorno-Karabakh conflict and economic concerns, environment-related concerns do not appear to be sufficient to motivate widespread violent conflict or citizen dissent related to environmental or natural resource conditions.  相似文献   

S-wave velocity structure, mantle xenoliths and the upper mantle beneath the Kaapvaal craton   总被引：1，自引：0，他引：1  

Angela Marie Larson  J. Arthur Snoke  David E. James 《Geophysical Journal International》2006,167(1):171-186

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Using Spatial Statistics to Examine the Pattern of Urban Land Development in Halifax–Dartmouth     

Angela L. Cuthbert  William P. Anderson 《The Professional geographer》2002,54(4):521-532

This article examines the locational patterns of population and employment and the resultant changes in urban form in the Halifax–Dartmouth region between 1970 and 1996. The article employs the univariate and bivariate K function to measure spatial dependence or clustering within and between the classes of residential and commercial land parcels. The results of the K function estimates suggest that residential land parcels cluster together, commercial land parcels cluster together, and residential and commercial land parcels have become more clustered over time. Evidence of clustering provides insight into the changing urban form of the region and possible multinucleation.  相似文献   

Geochronology of granulites from the south Itabuna-Salvador-Curaçá Block,São Francisco Craton (Brazil): Nd isotopes and U–Pb zircon ages     

Jean-Jacques Peucat  Johildo Salomão Figueiredo Barbosa  Ivana Conceição de Araújo Pinho  Jean-Louis Paquette  Hervé Martin  C. Mark Fanning  Angela Beatriz de Menezes Leal  Simone Cruz 《Journal of South American Earth Sciences》2011,31(4):397-413

This work provides five new U–Pb zircon dating and the corresponding Nd isotope data for felsic granulites from the south Itabuna-Salvador-Curaçá Block (ISCB), in the São Francisco Craton, Brazil. Three major sets of felsic granulites can be recognised. The oldest set is tonalitic in composition and of TTG affinity. It is Archaean in age with magmatic zircon cores dated at 2675 ± 11 Ma by LA-ICPMS and up to ca 2.7–2.9 Ga by SHRIMP on an other sample. It exhibits epsilon Nd values between ?8 and ?11 at 2.1 Ga. This Nd signature is similar to that of granulites found in the western Archaean Jequié Block. Cartographically, this set of Archaean terrains represents at least 50% of the granulites in the studied area. The second set corresponds to a Palaeoproterozoic calc-alkaline tonalitic suite with zircon ages from 2019 ± 19 Ma to 2191 ± 10 Ma and epsilon Nd values between ?3 and ?4 at 2.1 Ga, corresponding partially to a newly formed crust. The third set of granulites is also Palaeoproterozoic. It is shoshonitic to monzonitic in composition and synchronous with the high grade metamorphism dated by metamorphic zircons at 2086 ± 7 Ma (average of five samples). The Nd isotope signature for this alkaline set is similar to that of the Palaeoproterozoic calc-alkaline one. Nd isotopes appear to be a very efficient tool to distinguish Archaean from Palaeoproterozoic felsic protoliths in granulitic suites of the Itabuna-Salvador-Curaçá Block (ISCB). Finally, the southern part of the ISCB is composed of a mixture of Archaean and Palaeoproterozoic protoliths, in similar amounts, suggesting that it was probably an active margin between 2.1 and 2.2 Ga located on the eastern border of the Archaean Jequié Block. A major crustal thickening process occurred at ca 2.09 Ga in the ISCB and seems significantly younger towards the west, in the Jequié granulites, where an average of 2056 ± 9 Ma is determined for the high grade event.  相似文献