Effects of exposure to four endocrine disrupting-chemicals on fertilization and embryonic development of Barbel chub (Squaliobarbus curriculus)     

NIU Cuijuan  WANG Wei  GAO Ying  LI Li 《中国海洋大学学报(英文版)》2013,12(3):491-499

The toxicities of 4 common endocrine-disrupting chemicals (EDCs), 17β-estradiol (E2), p,p′-dichlorodiphenyldichloro-ethylene (DDE), 4-nonylphenol (NP) and tributyltin (TBT), to sperm motility, fertilization rate, hatching rate and embryonic development of Barbel chub (Squaliobarbus curriculus) were investigated in this study. The duration of sperm motility was significantly shortened by exposure to the EDCs at the threshold concentrations of 10 ng Lp>?1p> for E2 and TBT, 1 μg Lp>?1p> for NP and 100 μg Lp>?1p> for DDE, respectively. The fertilization rate was substantially reduced by the EDCs at the lowest observable effect concentrations (LOECs) of 10 ng Lp>?1p> for E2 and TBT and 10 μg Lp>?1p> for DDE and NP, respectively. Of the tested properties of S. curriculus, larval deformity rate was most sensitive to EDC exposure and was significantly increased by DDE at the lowest experimental level of 0.1 μg Lp>?1p>. Other EDCs increased the larval deformity rate at the LOECs of 1 ng Lp>?1p> for E2, 10 ng Lp>?1p> for TBT and 1 μg Lp>?1p> for NP, respectively. Despite their decreases with the increasing EDC concentrations, the hatching rate and larval survival rate of S. curriculus were not significantly affected by the exposure to EDCs. The results indicated that all the 4 EDCs affected significantly and negatively the early life stages of the freshwater fish S. curriculus. Overall, E2 and TBT were more toxic than NP and DDE, while DDE might be more toxic to larval deformity rate than to other measured parameters. Thus, the 4 EDCs showed potential negative influences on natural population dynamics of S. curriculus. Our findings provided valuable basic data for the ecological risk assessment of E2, DDE, NP and TBT.  相似文献   

大型石化建设工程（广西石化）项目管理信息系统应用实战剖析     

章洪波 《中国勘察设计》2009,(1):36-39

中国石油广西石化1000万t/a炼油项目参与各方人员共同使用p3e/c软件编制完成了该项目基础设计、详细设计、采购、施工、试车等整个项目各装置各级网络计划。阐述了应用p3e/c软件在该项目计划、进度与费用控制实战中的计划目标的建立、控制与应用,旨在为同类项目在计划、进度与费用控制上起到抛砖引玉的作用。广西石化1000万t/a炼油项目的计划管理工作吸取了国际上先进的项目管理经验及方法,全面采用了p3e/c软件作为计划管理工具,并充分结合了目前国内施工管理的实际水平,探索出国内大型新建炼油项目计划管理工作的新路,使广西石化1000万t/a炼油项目的计划管理工作处于国内领先的位置。  相似文献   

AR模型在大地电磁测深资料处理中的应用     

张春虹  张刚 《地球物理学进展》2013,28(3):1227-1233

大地电磁测深资料数据采集过程中,由于温度、湿度等对仪器的影响或GPS搜星不正常,采集到的数据有时会出现时间序列跳帧或缺失现象.针对这一问题,本文将基于无激励AR(p)模型预测数据的原理引入大地电磁测深数据处理中.根据已知序列确定AR(p)模型阶数以及模型参数,建立正确的预测模型对缺失数据进行预测,并对比经过预测后的数据与实际样本数据的频谱,表明AR(p)预测模型可以解决原始资料的不连续性问题,提高了大地电磁测深野外资料的利用率.  相似文献   

Modeling vp and Q on Explosion Seismology Data in NE Tibet     

A. Galvé  A. Hirn  J. Gallart  Jiang Mei  Wang Youxue WT  ”BX 《地学前缘》2000,(Z1)

MODELING v_P AND Q ON EXPLOSION SEISMOLOGY DATA IN NE TIBET  相似文献   

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李红  陈连旺  李玉江 《大地测量与地球动力学》2008,28(2):39-44

?????????????????????????????????????GPS????????????????????????????????????????4?????????????????????????????????????????????????????????????????????????壻??????????????????????????????????????????壻?齭???????????????????????????????????塣???????????????????????ζ?????????????????????????????????????????????κ??齭???????????????????????????????????????????????  相似文献   

u‐p semi‐Lagrangian reproducing kernel formulation for landslide modeling          下载免费PDF全文

Thanakorn Siriaksorn  Sheng‐Wei Chi  Craig Foster  Ashkan Mahdavi 《国际地质力学数值与分析法杂志》2018,42(2):231-255

This paper presents a u‐p (displacement‐pressure) semi‐Lagrangian reproducing kernel (RK) formulation to effectively analyze landslide processes. The semi‐Lagrangian RK approximation is constructed based on Lagrangian discretization points with fixed kernel supports in the current configuration. As a result, it tracks state variables at discretization points while allowing extreme deformation and material separation that is beyond the capability of Lagrangian formulations. The u‐p formulation following Biot theory is incorporated into the formulation to describe poromechanics of saturated geomaterials. In addition, a stabilized nodal integration method to ensure stability of the domain integration and kernel contact algorithms to model contact between bodies are introduced in the u‐p semi‐Lagrangian RK formulation. The proposed method is verified with several numerical examples and validated with an experimental result and the field data of an actual landslide.  相似文献   

North Indian Ocean warming and sea level rise in an OGCM     

Bijoy Thompson  C. Gnanaseelan  Anant Parekh  P. S. Salvekar 《Journal of Earth System Science》2008,117(2):169-178

The variability in the long-term temperature and sea level over the north Indian Ocean during the period 1958–2000 has been investigated using an Ocean General Circulation Model, Modular Ocean Model version 4. The model simulated fields are compared with the sea level observations from tide-gauges, Topex/Poseidon (T/P) satellite, in situ temperature profile observations from WHOI moored buoy and sea surface temperature (SST) observations from DS1, DS3 and DS4 moored buoys. It is seen that the long (6–8 years) warming episodes in the SST over the north Indian Ocean are followed by short episodes (2–3 years) of cooling. The model temperature and sea level anomaly over the north Indian Ocean show an increasing trend in the study period. The model thermocline heat content per unit area shows a linear increasing trend (from 1958–2000) at the rate of 0.0018 × 10p>11p> J/mp>2p> per year for north Indian Ocean. North Indian Ocean sea level anomaly (thermosteric component) also shows a linear increasing trend of 0.31 mm/year during 1958–2000.  相似文献   

P16^INK4A联合HPV L1壳蛋白检测在宫颈鳞状上皮内病变诊断中的应用     

潘琼慧  郑翔  何海珍  朱雪燕  胡仙清  朱雪琼 《寒旱区科学》2017,9(5):104-108,69

目的 初步探讨P16p>INK4Ap>联合HPV L1壳蛋白检测在宫颈鳞状上皮内病变诊断中的应用价值。方法 选择在温州市人民医院就诊患者,收集69例宫颈鳞状上皮内病变标本,行P16p>INK4Ap>、HPV L1壳蛋白检测,分析P16p>INK4Ap>、HPV L1壳蛋白及P16p>INK4Ap>联合HPV L1壳蛋白在各级宫颈病变中的表达差异。结果 P16p>INK4Ap>在LSIL组、HSIL组、SCC组中的阳性率分别为45.5%、85.2%、100.0%。同LSIL组比较,P16p>INK4Ap>在HSIL组及SCC组阳性率明显升高（P<0.01）。HPV L1壳蛋白在LSIL组、HSIL组、SCC组中的阳性率分别为63.6%、18.5%、0%,HPV L1壳蛋白在LSIL组中阳性率明显低于HSIL组及SCC组（P<0.01）。随着宫颈病变加重,P16+/L1-阳性率有升高趋势（P<0.01）,P16-/L1+阳性率有下降趋势（P<0.01）。LSIL组中P16+/L1-阳性率明显低于HSIL组和SCC组（P<0.01）,SCC组P16+/L1-阳性率较HSIL组有明显提高（P<0.05）。LSIL组中P16-/L1+阳性率明显低于HSIL组和SCC组（P<0.01）。P16+/L1-较P16p>INK4p>、HPV L1壳蛋白单一检测筛查HSIL+特异性明显升高（P<0.01）。结论 P16p>INK4Ap>联合HPV L1壳蛋白有望成为诊断宫颈鳞状上皮内病变的有效指标。  相似文献   

Timing of low-temperature metamorphism and cooling of the Paleozoic and Mesozoic formations of the Bükkium,innermost Western Carpathians,Hungary     

P. Árkai  K. Balogh  I. Dunkl 《International Journal of Earth Sciences》1995,84(2):334-344

K-Ar ages of illite-muscovite and fission track ages of zircon and apatite were determined from various lithotypes of the B&amp;uuml;kkium, which forms the innermost segment of the Western Carpathians. The stratigraphic ages of these Dinaric type formations cover a wide range from the Late Ordovician up to the Late Jurassic. The grade of the orogenic dynamo-thermal metamorphism varies from the late diagenetic zone through the p548584w3m12784t/xxlarge8216.gif" alt="lsquo" align="BASELINE" BORDER="0">anchizonep548584w3m12784t/xxlarge8217.gif" alt="rsquo" align="BASELINE" BORDER="0"> up to the p548584w3m12784t/xxlarge8216.gif" alt="lsquo" align="BASELINE" BORDER="0">epizonep548584w3m12784t/xxlarge8217.gif" alt="rsquo" align="BASELINE" BORDER="0"> (chlorite, maximally biotite isograd of the greenschist facies). The K-Ar system of the illite-muscovite in the < 2 p548584w3m12784t/xxlarge956.gif" alt="mgr" align="MIDDLE" BORDER="0">m grain-size fraction approached equilibrium only in p548584w3m12784t/xxlarge8216.gif" alt="lsquo" align="BASELINE" BORDER="0">epizonalp548584w3m12784t/xxlarge8217.gif" alt="rsquo" align="BASELINE" BORDER="0"> and high-temperature p548584w3m12784t/xxlarge8216.gif" alt="lsquo" align="BASELINE" BORDER="0">anchizonalp548584w3m12784t/xxlarge8217.gif" alt="rsquo" align="BASELINE" BORDER="0"> conditions. The orogenic metamorphism culminated between the eo-Hellenic (160-120 Ma) phase connected to the beginning of the subduction in the Dinarides, and the Austrian (100-95 Ma) phase characterized by compressional crustal thickening. No isotope geochronological evidence was found for proving any Hercynian recrystallization. The stability field of fission tracks in zircon was approached using the thermal histories of the different tectonic units. A temperature less than 250&amp;deg;C and effective heating time of 20&amp;#x2013;30 Ma had only negligible effects on the tracks, whereas total annealing was reached between 250 and 300&amp;deg;C. Apatite fission track ages from the Paleozoic and Mesozoic formations show that the uplift of the B&amp;uuml;kk Mountains occurred only in the Tertiary (not earlier than ca. 40 Ma ago). Thermal modeling based on apatite fission track length spectra and preserved Paleogene sediment thickness data proved that the Late Neogene burial of the recently exhumed plateau of the B&amp;uuml;kk Mountains exceeded 1 km.  相似文献   

Properties of theβ pictoris disc deduced from optical imaging polarimetry     

Ramon D. Wolstencroft  S. M. Scarrott  T. M. Gledhill 《Astrophysics and Space Science》1995,224(1-2):395-398

The asymmetries in the brightness structure and levels of polarization between the two sides of thep8ll60/xxlarge946.gif" alt="beta" align="MIDDLE" BORDER="0"> Pic disc are discussed. The possibility of these differences being caused by a planet, or planets, within the circumstellar disc is investigated.  相似文献