Trace elements in ferromanganese nodules from the central indian ocean basin     

J. N. Pattan  G. Parthiban  Ankeeta Amonkar  Sufiyan A. Shaikh  S. Jai Sankar 《Marine Georesources & Geotechnology》2017,35(8):1147-1157

Thirty-three bulk ferromanganese nodules from the sediment–water interface of siliceous sediment domain from the Central Indian Ocean Basin were analyzed for 50 elements including 6 new (Be, As, Se, Sn, Sb, and Bi) using inductively coupled plasma–mass spectrometer. The Mn/Fe ratio and triangular plot (Fe-Mn-{Cu+Ni+Co?×?10}) suggest that ferromanganese nodules are of hydrogenetic, early diagenetic, and diagenetic origin. In the ferromanganese nodules, Mo, Sb, Bi, and As are highly enriched ～320, 160, 90, and 50 times compared with upper continental crust, respectively. A majority of the elements such as Be, Sc, Ti, V, Co, As, Se, Sr, Y, Zr, Nb, Sn, rare earth elements (REEs), Pb, Bi, P, Th, U, Hf, and Ta are associated with Fe, whereas, Cu, Ni, Zn, Mo, Li, Ga, Sb, Mg, and Cs are associated with Mn in the ferromanganese nodules. Redox proxies such as U/Th (0.14) and Mo/Mn (0.0019) ratio in the ferromanganese nodules suggest their formation under oxic conditions.  相似文献   

藻蓝蛋白对博来霉素肺纤维化小鼠肠道菌群的影响          下载免费PDF全文

臧帆  李文军  秦松  林剑 《海洋科学》2023,47(6):42-51

博来霉素(bleomycin,BLM)是目前用于治疗头颈癌等多种癌症的药物之一,但会产生一系列副作用,例如肺纤维化(pulmonary fibrosis,PF),这大大降低了患者的生活质量。藻蓝蛋白(phycocyanin,PC)作为一种色素蛋白对包括PF在内的多种疾病具有调节作用。研究发现,慢性肠道疾病通常伴有肺部疾病,患者的肠道菌群会发生紊乱。针对上述线索,研究了PC对BLM诱导的PF小鼠肠道菌群的影响。通过尾静脉将BLM注入小鼠体内,以构建肺纤维化模型。然后通过16S r RNA高通量基因测序技术,分析了PC对BLM引起的PF小鼠肠道菌群的影响。结果表明,PC降低了BLM诱导的PF程度并调节了小鼠的肠道菌群。通过尾静脉注射BLM后,小鼠肺部受到损伤,肠道菌群发生紊乱。口服藻蓝蛋白干预后,小鼠的肺组织切片显示其胶原蛋白沉积减少,肺泡间隔和炎性细胞浸润减少,小鼠PF程度减轻。此时,小鼠肠道菌群中Alistipes、Lachnospiraceae等有益菌的丰度增加,Rikenella等有害菌的丰度降低,肠道菌群趋于正常。推测PC可以通过增加肠道中有益细菌的数量并减少肠道中有害细菌的数量...  相似文献