Array technology as a tool to monitor exposure of fish to xenoestrogens     

Larkin P  Folmar LC  Hemmer MJ  Poston AJ  Lee HS  Denslow ND 《Marine environmental research》2002,54(3-5):395-399

A variety of anthropogenic chemicals are capable of binding to the estrogen receptor of vertebrate species. Binding of these compounds can interfere with homeostasis by disrupting normal gene expression patterns. The purpose of this study was to investigate the feasibility of applying array technology as a monitoring tool for detecting the presence and distribution of estrogenic compounds in coastal habitats using sheepshead minnows as our model. cDNA clones that were isolated from differential display, including vitellogenin alpha and beta, vitelline envelope protein (ZP2), and transferrin, among others, were spotted on the macroarray. The results of these experiments demonstrate a characteristic expression pattern of estrogen responsive genes in sheepshead minnows exposed to 17 beta-estradiol (E2).  相似文献   

人工蜂群算法的改进及在空间数据聚类中的应用     

施方林  李宏伟  朱燕  樊超 《测绘与空间地理信息》2017,(10):35-39

人工蜂群算法是一种新兴的群智能算法,具有灵活、易于与其他技术结合、设置参数少、实用性强的优点,但同时也存在一些缺陷,如蜜源更新和选择机制随意性较大,算法后期收敛速度慢等。本文在总结前人研究成果的基础上,从蜜源更新公式和选择机制两方面对基本的人工蜂群算法做出改进。算法的应用是蜂群算法研究的热点,本文采用位置-属性一体化概念模型,将空间属性与非空间属性纳入统一的空间计算模型,结合本文提出的改进的人工蜂群算法对Meuse数据集进行空间聚类分析,获得了比较好的结果。  相似文献   

南海东北部两种软珊瑚     

李楚璞 《热带海洋学报》1993,(2)

金黄编笠软珊瑚Morchellana boleliformis(Ridley)和黎明编笠软珊瑚Morchellana auroro(Ridley)隶属于棘软珊瑚科Nephtheidae编笠软珊瑚属Morchellana,于1979—1983年采自南海东北部水域。  相似文献   

华北克拉通中生代破坏前的岩石圈地幔与下地壳   总被引：23，自引：11，他引：12  

翟明国 《岩石学报》2008,24(10):2185-2204

华北克拉通是世界上最古老的克拉通之一,有 38亿年的古老陆壳存在,它经历了复杂的地质变迁,在太古宙末(约2500Ma)基本完成克拉通化,在古元古代(约1900~1850Ma)整体受到了高级变质作用,最终完成了克拉通化。它的东部在中生代发生了重大的构造机制的转变,克拉通基底发生了破坏、置换和再造。在太行山重力梯度带以西的华北克拉通受中生代构造转折的改造程度较低,它们的下地壳和岩石圈地幔结构,大致保持了华北克拉通破坏前的状态。前寒武纪麻粒岩地体代表了掀翻抬升到地表的古元古代下地壳,出露地表的时间大致在1850~1800Ma。中、新生代火山岩中的地幔和麻粒岩捕虏体代表了现代的岩石圈地幔和下地壳的岩石。岩石学、地球化学和地球物理的研究,推测华北克拉通西部的岩石圈厚约200km,地壳厚度约45km~50km,是在古元古代(约1.9Ga)时期终极克拉通化作用形成的,其厚度和结构与全球典型的元古宙克拉通岩石圈相同。而太行山重力梯度带以东的克拉通岩石圈地幔受到程度不等的交代、改造、置换和减薄,下地壳大规模重熔,地壳厚度也发生减薄,指示了强烈的壳幔解耦、物质交换和重新耦合的过程。  相似文献   

Life in the Goldilocks Zone: Perceptions of Place Disruption on the Periphery of the Bakken Shale     

Anne N. Junod  Jeffrey B. Jacquet  Felix Fernando  Lynette Flage 《社会与自然资源》2018,31(2):200-217

Community impacts from oil development in the Bakken Shale, located in the north central region of the United States, have been well reported in the press, including highly publicized accounts of social disruption. Less examined are communities on the periphery of such development, which experience related impacts unique to their location. Twenty-eight long-time residents from three Bakken periphery communities were interviewed to evaluate social and environmental impact perceptions, including perceived risks of place disruption. Findings suggest that whereas place meanings and identities were disrupted by the oil boom in Bakken core communities, they remain intact in these periphery communities. Findings further suggest periphery residents view their proximal location to the Bakken region as a social and economic “Goldilocks Zone:” close enough to benefit from spillover economic impacts, yet far enough away to avoid serious negative social impacts. This research extends understanding of place disruption and development impacts in energy periphery communities.  相似文献   

不同地磁匹配导航算法比较研究     

莫荣 《测绘与空间地理信息》2016,(10):46-48

地磁匹配导航的关键技术之一是稳定高效的匹配算法。本文将ICCP算法与蚁群智能算法在地磁匹配导航中的应用效果进行了仿真实验。实验结果表明:ICCP算法具有较好的全局性,但算法复杂,导致实效性差;蚁群算法搜索效率高,实效性强,具有较强的适用性和鲁棒性。从这个角度来说,蚁群算法更加适合于地磁匹配导航。  相似文献   

PHYSICAL PROPERTIES OF METEORITES AND INTERPLANETARY DUST PARTICLES: CLUES TO THE PROPERTIES OF THE METEORS AND THEIR PARENT BODIES     

George J. Flynn 《Earth, Moon, and Planets》2004,95(1-4):361-374

Meteorites, generally 1 cm or larger in size that are believed to sample asteroids, and interplanetary dust particles (IDPs), generally 5–50 μm in size that are believed to sample both asteroids and comets, span the size range of the meteors. Thus, the physical properties of the meteorites and the IDPs are likely to constrain the properties of the meteors and their parent bodies. Measurements of the density, porosity, longitudinal and transverse speeds of sound, elastic modulus, and bulk modulus, as well as imaging of the internal structure by Computed Microtomography indicate that unweathered samples of chondritic meteorites are more porous and have lower sound velocities than compact terrestrial rocks. In general, the IDPs are even more porous than the chondritic meteorites. The impact energy per unit target mass required to produce a barely catastrophic disruption (Q ^* _D) for anhydrous ordinary chondrite meteorites is twice that for terrestrial basalt or glass, indicating that collisional disruption of anhydrous meteorites requires more energy than for a compact basalt. These results indicate that most stone meteors are likely to be weak, porous objects, and that the parent bodies of the anhydrous stone meteorites are likely to be more difficult to disrupt than compact terrestrial basalt.  相似文献   

Prediction of berm geometry using a set of laboratory tests combined with teaching–learning-based optimization and artificial bee colony algorithms     

《Applied Ocean Research》2014

Understanding sediment movement in coastal areas is crucial in planning the stability of coastal structures, the recovery of coastal areas, and the formation of new coast. Accretion or erosion profiles form as a result of sediment movement. The characteristics of these profiles depend on the bed slope, wave conditions, and sediment properties. Here, experimental studies were performed in a wave flume with regular waves, considering different values for the wave height (H₀), wave period (T), bed slope (m), and mean sediment diameter (d₅₀). Accretion profiles developed in these experiments, and the geometric parameters of the resulting berms were determined. Teaching–learning-based optimization (TLBO) and artificial bee colony (ABC) algorithms were applied to regression functions of the data from the physical model. Dimensional and dimensionless equations were found for each parameter. These equations were compared to data from the physical model, to determine the best equation for each parameter and to evaluate the performances of the TLBO and ABC algorithms in the estimation of the berm parameters. Compared to the ABC algorithm, the TLBO algorithm provided better accuracy in estimating the berm parameters. Overall, the equations successfully determined the berm parameters.  相似文献   

Inhibition of Aspergillus parasiticus and cancer cells by marine actinomycete strains     

Ping Li  Peisheng Yan 《中国海洋大学学报(英文版)》2014,13(6):985-994

Ten actinomycete strains isolated from the Yellow Sea off China's coasts were identified as belonging to two genera by 16 S r DNA phylogenetic analysis: Streptomyces and Nocardiopsis. Six Streptomyces strains(MA10, 2SHXF01-3, MA35, MA05-2, MA05-2-1 and MA08-1) and one Nocardiopsis strain(MA03) were predicted to have the potential to produce aromatic polyketides based on the analysis of the KSα(ketoacyl-synthase) gene in the type II PKS(polyketides synthase) gene cluster. Four strains(MA03, MA01, MA10 and MA05-2) exhibited significant inhibitory effects on mycelia growth(inhibition rate 50%) and subsequent aflatoxin production(inhibition rate 75%) of the mutant aflatoxigenic Aspergillus parasiticus NFRI-95. The ethyl acetate extracts of the broth of these four strains displayed significant inhibitory effects on mycelia growth, and the IC50 values were calculated(MA03: 0.275 mg m L-1, MA01: 0.106 mg m L-1, MA10: 1.345 mg m L-1 and MA05-2: 1.362 mg m L-1). Five strains(2SHXF01-3, MA03, MA05-2, MA01 and MA08-1) were selected based on their high cytotoxic activities. The ethyl acetate extract of the Nocardiopsis strain MA03 was particularly noted for its high antitumor activity against human carcinomas of the cervix(He La), lung(A549), kidney(Caki-1) and liver(Hep G2)(IC50: 2.890, 1.981, 3.032 and 2.603 μg m L-1, respectively). The extract also remarkably inhibited colony formation of He La cells at an extremely low concentration(0.5 μg m L-1). This study highlights that marine-derived actinomycetes are a huge resource of compounds for the biological control of aflatoxin contamination and the development of novel drugs for human carcinomas.  相似文献   

A bottom‐up approach to discover transition rules of cellular automata using ant intelligence     

Xiaoping Liu  Lin Liu  Jinqiang He  Bin Ai 《International journal of geographical information science》2013,27(11-12):1247-1269

This paper presents a new method to discover transition rules of geographical cellular automata (CA) based on a bottom‐up approach, ant colony optimization (ACO). CA are capable of simulating the evolution of complex geographical phenomena. The core of a CA model is how to define transition rules so that realistic patterns can be simulated using empirical data. Transition rules are often defined by using mathematical equations, which do not provide easily understandable explicit forms. Furthermore, it is very difficult, if not impossible, to specify equation‐based transition rules for reflecting complex geographical processes. This paper presents a method of using ant intelligence to discover explicit transition rules of urban CA to overcome these limitations. This ‘bottom‐up’ ACO approach for achieving complex task through cooperation and interaction of ants is effective for capturing complex relationships between spatial variables and urban dynamics. A discretization technique is proposed to deal with continuous spatial variables for discovering transition rules hidden in large datasets. The ACO–CA model has been used to simulate rural–urban land conversions in Guangzhou, Guangdong, China. Preliminary results suggest that this ACO–CA method can have a better performance than the decision‐tree CA method.  相似文献