排序方式: 共有49条查询结果,搜索用时 93 毫秒
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王佳 《中国海洋湖沼学报》1998,16(2):183-188
ImODUcrIONIngeneral,fOrmosttypesofinhibitorstheperformancecanbecontinuouslyheight-enedbyincreasingtheconeentration.Thehighertheinhibitorconcentration,thestrongertheinhibitionbomes.However,nantobservationsshowedthatsometypesofinhibitorsexhibitedbotperformanceonlywithinashortediumrangeofinhibitorconcentrationinsulfuricaddso1ution,whichistheso-cailedphenornenonofinhibitorconcenhation-indutalextreminhibition.EpelbOin(l979)reportedthattheinhibitingeffidenCyrnaxdrindataroundlmml4ofpropargylalcoh… 相似文献
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Blanck H Eriksson KM Grönvall F Dahl B Guijarro KM Birgersson G Kylin H 《Marine pollution bulletin》2009,58(2):230-237
Irgarol is a triazine photosystem II (PSII) inhibitor that has been used in Sweden as an antifouling ingredient since the 1990s. Early microcosm studies indicated that periphyton was sensitive to irgarol at concentrations regularly found in harbours and marinas. However, field studies of irgarol effects on the Swedish west coast in 1994, using the pollution-induced community tolerance (PICT) approach, failed to detect any effects of the toxicant in the field. A PICT study involves sampling of replicate communities in a gradient of contamination, and a comparison of their community tolerance levels, with an increase being an indication that sensitive species have been eliminated and replaced by more tolerant ones. Typically, short-term assays are used to quantify the community tolerance levels. Later PICT studies in the same area over a 10 year period demonstrate that irgarol tolerance levels have increased, although the contamination pattern has been stable. Our results support the hypothesis that that the PICT potential was low initially, due to a small differential sensitivity between the community members, and that a persistent selection pressure was required to favour and enrich irgarol-tolerant species or genotypes. 相似文献
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青虾(Macrobrachium nipponense)Kazal型丝氨酸蛋白酶抑制因子基因全长cDNA的克隆及表达 总被引:2,自引:0,他引:2
采用RACE技术,首次从青虾精巢中克隆得到KSPI基因全长cDNA。青虾KSPI基因cDNA全长890bp,包括80bp的5′UTR,546bp的3′UTR和编码87个氨基酸残基的264bp开放阅读框。预测蛋白包含1个保守的Kazal型结构域(CⅠX5CⅡX(6)VCⅢX(5)TYXNXCⅣX6CⅤX12CⅥ),结构域中P1活性位点为苏氨酸残基。应用MEGA4.1软件对青虾与已报道的虾类共15种KSPI氨基酸序列进行系统进化分析,结果表明,青虾KSPI与同样来源于精巢的罗氏沼虾KSPI进化关系最近聚为一支,其它虾类来源于肝胰腺和血细胞的KSPI聚为另外两支。采用定量PCR技术分析其组织分布,结果显示,KSPI基因在精巢、心脏和卵巢中有较高表达,其中精巢表达水平极高,并与心脏和卵巢表达差异分别达到显著(P<0.05)和极显著(P<0.01)水平,其它组织表达较弱。 相似文献
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Thrombin,the ultimate proteinase of the coagulation cascade,is an attractive target for the treatment of a variety of cardiovascular diseases.A bromophenol derivative named (+)-3-(2,3-dibromo-4,5-dihydroxy-phenyl)-4-bromo-5,6-dihydroxy-1,3-dihydroiso-benzofuran 1,isolated from the brown alga Leathesia nana exhibited significant thrombin inhibitory activity.In this study,we investigated the inhibition of human thrombin in vitro with this bromophenol derivative,and its antithrombotic efficacy in vivo using th... 相似文献
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深水区油气钻完井作业相比浅水区和陆地遇到了很多难题,由于海底压力增大和低温的环境,天然气水合物已成为影响深水钻井安全的主要危害之一。目前,国际上深水钻完井作业中通常采用油基钻井液来防水合物,但是油基钻井液环保风险高,为此在陵水区块超深水钻完井作业中尝试采用水基钻完井液进行作业。鉴于国内无类似经验可循,结合陵水区块超深水井的实际情况,首先模拟分析了2口井的水合物风险,明确该区块水合物形成的条件;其次,针对水合物形成的风险,筛选合适的抑制剂及钻完井液配方;在此基础上,研究出相配套的工艺措施。陵水区块深水钻井作业的成功实践表明,由此形成的一套深水水基钻完井液防水合物技术在深水钻完井作业中能够较好地防治天然气水合物,保障作业安全,对后续类似深水井的作业具有借鉴意义。 相似文献
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海水循环冷却系统腐蚀、污垢和菌藻控制技术研究 总被引:4,自引:0,他引:4
海水循环冷却技术,是海水资源利用领域一项新技术,属于海水直接利用技术的范畴。海水含盐量高,具有腐蚀和结垢性的离子浓度远高于一般淡水,且微生物和大生物的种类多、含量高,远不符合国家标准《工业循环冷却水处理设计规范》规定的循环冷却水的水质要求,但是,海水循环冷却技术实验室研究表明,通过添加海水缓蚀剂,阻垢分散剂,菌藻杀生剂等海水水处理药剂,在腐蚀控制,污垢控制,菌藻控制等方面,可以达到或接近国家有关标准规定的技术指标要求。 相似文献
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Yoshihiro Yokoyama Hiroshi Tsukamoto Tohru Suzuki Shohshi Mizuta Reiji Yoshinaka 《中国海洋大学学报(英文版)》2005,4(3):214-218
In this study, genes of two distinct tissue inhibitors of metalloproteinases-2 (TIMP-2) from Japanese puffer fish Fugu rubripes, Fugu TIMP-2a and TIMP-2b, were cloned. The open reading frames of Fugu TIMP-2a and TIMP-2b cDNAs are composed of 660 and 657 nucleotides and 220 and 219 amino acids, respectively. Both Fugu TIMP-2s contain 12 cysteine residues, which might form six disulfide bonds as in other animals' TIMP-2s. Reverse-transcribed polymerase chain reaction analysis showed the mRNAs of Fugu TIMP-2a and TIMP-2b to be expressed in some tissues examined with different expression patterns. These findings suggest that the two distinct Fugu TIMP-2s might perform different functions in Fugu tissues. 相似文献