广盐性鱼类渗透压适应性与生理可塑性机制研究     

马爱军  崔文晓  刘志峰  张金生  黄智慧  杨双双  刘晓菲  杨凯  张薇 《海洋与湖沼》2018,49(6):1308-1317

拥有强大的渗透压调节能力对广盐性鱼类的生存至关重要。目前,关于鱼类渗透压调节机制已有不少研究,但均存在较大的局限性。本文从广盐性鱼类渗透压信号转导机制、渗透胁迫的细胞调控机制、渗透调控的内分泌调节机制和无机离子通道和转运蛋白介导的渗透调控等方面对广盐性鱼类的渗透压适应性和生理可塑性机制进行分析,以期从分子、细胞、通路和生理等层次初步探索广盐性鱼类盐度胁迫后的可塑性表型变化和不同盐度条件下的应答机制,为广盐性鱼类的渗透压调节机制的深入研究奠定基础。对广盐性鱼类渗透压适应性与生理可塑性机制研究,有助于研究其环境适应机理,促进野生鱼种的人工化养殖以及新品种的育种从而提高经济效益、社会效益和生态效益,对促进水产养殖学进步以及养殖业的发展具有重要意义,同时,为研究广盐性鱼类的渗透压调节机制开辟新的研究方向。  相似文献   

Origin of Oils in “Subtle pools” in the Dongying Depression, Bohai Bay Basin, China     

Li Sumei  Jiang Zhengxue  Liu Keyu  Qiu Guiqiang  Gao Yongjin 《《地质学报》英文版》2008,82(1):184-196

Subtle traps or oil pools have become an important exploration play in the Dongying Depression, Bohai Bay Basin, east China. Despite recent successes in exploration, the formation mechanisms of subtle traps are still not well understood. The majority of subtle oil pools in the Dongying Depression are developed in the middle interval of the Es3 Member of the Paleogene Shahejie Formation with the subtle traps being primarily of lenticular basin-floor turbidite sands encompassed in mudstones. Oil in the subtle traps was previously thought to have migrated directly from the surrounding source rocks of the same formation （Es3）. Detailed geochemical investigation of 41 oils and 41 rock samples from the depression now indicates that the oils from the subtle traps cannot be correlated well with the surrounding Es3 source rocks, which are characterized by high Pr/ Ph （〉1）, low Gammacerane/C30hopane, representing a freshwater lacustrine setting. In contrast the oils features low Pr/Ph （〈1） and relatively high Gammacerane content, showing a genetic affinity with the underlying Es4 source rocks, which also have the same qualities, indicating a brackish lacustrine setting. Oils in the Es3 subtle traps are probably derived from mixed sources with the contribution from the upper Es4 source rocks predominating. Therefore unconventional oil migration and accumulation mechanisms need to be invoked to explain the pooling of oils from the ES4 source rocks, which probably came through a thick low interval of the Es3 source rocks with no apparent structural or stratigraphic pathways. We suggest that the subtle oil migration pathway probably plays an important role here. This finding may have significant implications for future exploration and the remaining resource evaluation in the Dongying Depression.  相似文献   

The Glarus thrust: excursion guide and report of a field trip of the Swiss Tectonic Studies Group (Swiss Geological Society, 14.–16. 09. 2006)     

Marco Herwegh  Jean-Pierre Hürzeler  O. Adrian Pfiffner  Stefan M. Schmid  Rainer Abart  Andreas Ebert 《Swiss Journal of Geoscience》2008,101(2):323-340

This excursion guide results form a field trip to the Glarus nappe complex organized by the Swiss Tectonic Studies Group in 2006. The aim of the excursion was to discuss old and recent concepts related to the evolution of the Glarus thrust. The major aspects were (i) the interplay between deformation, fluid flow and geochemical alteration, (ii) episodic versus continuous deformation and fluid flow, and (iii) the link between large-scale structures, microstructures, and geochemical aspects. Despite 150 years of research in the Glarus nappe complex and the new results discussed during the excursion, there exist controversies that still are unsolved.  相似文献   

Quantification of the risk associated with high levels of mercury pollution at Temirtau, Kazakhstan     

Huiwen HSIAO Susanne M. Ullrich Trevor W. Tanton 《中国地球化学学报》2006,25(B08):233-233

This research aims to establish the risks of hurnan exposure to modeling approach. The study site was located on the River Nura 1990s, an acetaldehyde production plant located in the industrial high environmental mercury levels, based on a quantitative risk in central Kazakhstan. From the 1950s until its closure in the mid city of Temirtau released mercury-containing wastewater into the river. River sediments are highly contaminated with mercury up to a distance of 25 km and beyond. In addition, a local power station released an estimated 6 million tonnes of fly-ash into the water and the mercury has become quite tightly associated with the ash deposits. River water, fish and agricultural land in the floodplain are also contaminated with mercury, yet the risks posed to the local population have not been evaluated to date. In June and July 2005, we took samples of soil, interior and exterior dust, drinking water, and food from individual households, communal areas and markets. Additionally, water and sediment samples and fish were taken from the river. Interviews were conducted with householders to establish their age and body weight, general living conditions and sources of irrigation and drinking water. A food frequency questionnaire （FFQ） was designed to investigate the frequencies of consumption of several common regional food items, including fish from the fiver and/or local market. Human hair samples were also collected to estimate the mercury bioburden and to enable the validity of the modeling approach to be established. The paper expands on the main pathways of contamination and looks at linkages between exposure pathways and mercury concentrations found in human hair. Uncertainties inherent in risk analysis as well as their influence on the relative importance of different exposure routes are also discussed.  相似文献   

油气成藏机理研究进展和前沿研究领域   总被引：23，自引：7，他引：23  

郝芳  邹华耀  王敏芳  杨旭升 《地质科技情报》2002,21(4):7-14

随着地质工作者刻划和认识地下地质体构成、结构的能力及研究和预测沉积盆地能量场（温度场、压力场和应力场）及其演化能力的不断提高，以流体流动和油气运移为核心的油气成藏机理研究取得了重要进展：（1）证实了油气的优势通道运移并妆步提示了优势运移通道的微观和宏观控制机制，从而使基于油气运移路径三维预测的油气藏定位预测成为可能；（2）证实了幕式快速成藏过程并初步揭示了幕式成藏的驱动机制、有利场所和地球化学识别标志，突破了油气成藏是一个缓慢渗流过程的传统模式；（3）深盆气勘探和成藏机理研究取得了进展，从而突破了背斜成藏的传统观念，使“向斜”（盆地凹陷区）成为一些盆地寻找大型天然气藏的重要场所。沉积盆地深层油气成藏过程和保存条件、活动构造背景下油气晚期快速成藏过程是油气成藏机理研究的重要前沿研究领域。  相似文献   

柴达木盆地三湖地区第四系生物气的形成途径与运聚方式   总被引：22，自引：1，他引：22  

张晓宝  徐自远  段毅  马立元  孟自芳  周世新  贺鹏 《地质论评》2003,49(2):168-174

柴达木盆地三湖(台吉乃尔湖、涩聂湖、达布逊湖)地区第四系生物气区是我国最大的生物气区。笔者系统采集了该气区21个天然气样品,测量了其组分和碳同位素组成,重点探讨了生物气形成途径和运聚方式。生物气δ~(13)C_1和δ~(13)C_(CO_2)均随深度增大而变重,显示了CO_2还原途径成气的特征。生物气δ~(13)C_1、δ~(13)C_(CO_2)和δD分布与CO_2还原方式形成的生物气的相应同位素值分布范围接近。在有关成因图解中这些数据主要位于CO_2还原途径成气范围内。生物气CO_2和CH_4之间的碳同位素分馏系数α_c>1.055,具有CO_2还原途径成气的特征。柴达木盆地第四纪干旱的古气候、较低的古温度、较高的沉积速率和水体中较高的硫酸盐含量使得甲烷菌的大量繁殖只能在较大的深度范围内才能实现,从而,有利于CO_2还原途径成气作用进行。涩北一号、涩北二号气田生物气δ~(13)C_1组成分布可能表明,生物气形成以后沿疏导层水平运移进入气藏,基本不存在垂向运移。该项研究对于进一步深入探讨生物气成因、形成条件,确定生物气模拟实验方式与条件,计算生物气资源量,建立成藏模式和选择天然气有利勘探区块均具有重要价值。  相似文献   

An Algorithm for the Determination of All Significant Pathways in Chemical Reaction Systems     

Ralph Lehmann 《Journal of Atmospheric Chemistry》2004,47(1):45-78

When the output of a complex chemical model is analysed, a typical topic isthe determination of pathways, i.e., reaction sequences, that produce ordestroy a chemical species of interest.A representative example is the investigation of catalytic ozone destruction cycles in the stratosphere.An algorithm for the automatic determination of pathways in any given reactionsystem is presented. Under the assumption that reaction rates are known, it finds all significant pathways, i.e., all pathways with a rate above a prescribed threshold.The algorithm forms pathways step by step, starting from single reactions.The chemical species in the system are consecutively considered as `branching points'.For every branching-point species, each pathway producing it is connected witheach pathway consuming it.Rates proportional to `branching probabilities' are calculated.Pathways with a rate that is smaller than a prescribed threshold arediscarded.If a newly formed pathway contains sub-pathways, e.g., null cycles, it is split into these simpler pathways.In order to demonstrate the performance of the algorithm, it has been applied to the determination of catalytic ozone destruction cycles and methaneoxidation pathways in the stratosphere.  相似文献   

透明胞外聚合颗粒物碳输运新途径   总被引：2，自引：1，他引：1  

孙军  郭聪聪  张桂成 《海洋学报》2019,41(8):125-130

目前大家普遍认为，透明胞外聚合颗粒物(Transparent Exopolymer Particles，TEP)因其独特的凝聚效应导致碳通量向海底输出。但是，近几年的研究表明TEP不仅影响了碳沉降途径，其本身能够悬浮甚至向海水表层迁移，导致其在海洋微表层(Surface Micro-layer, SML)积累，最终显著影响海洋表层碳通量。TEP和其他颗粒物聚集形成凝聚物后，其运动趋势则由凝聚物中TEP的含量占比，即最终颗粒物密度所决定。一个新的值得注意的现象是，密度低的TEP通过与其他微粒聚合形成表面活性物质(Surface-active Substances, SAS)，会在海洋–大气界面形成薄膜，显著影响海–气CO₂交换通量，甚至对全球气候变化造成影响。  相似文献   

香鱼(Plecoglossus altivelis)脾脏酪氨酸激酶SYK的鉴定及其介导的MAPK信号通路研究     

孙娇  聂力  苗亮  陈炯 《海洋与湖沼》2020,51(5):1182-1193

脾脏酪氨酸激酶(SYK)是一种非受体型酪氨酸激酶(non-receptor tyrosine kinase, NRTK)。在哺乳动物中,SYK是重要的细胞信号通路接头分子,其在免疫细胞活化,胞外刺激的信号转导和病原体识别等多种生命过程中扮演重要角色,然而在鱼类中却鲜有报道。本研究以香鱼(Plecoglossus altivelis)为研究对象,探讨了其SYK(PaSYK)在应对病原微生物感染及在活化免疫信号通路中的作用。我们克隆获得了香鱼SYK的cDNA序列,并利用多重序列比对、构建进化树等生物信息学方法分析PaSYK的进化地位;采用实时荧光定量PCR(RT-qPCR)方法分析PaSYK在健康组织及鳗弧菌(Vibrio anguillarum)感染后的表达变化;亚细胞定位检测PaSYK在HEK293T细胞的分布情况;在香鱼头肾单核/巨噬细胞(Monocyte/macrophage,MO/MΦ)中过表达PaSYK,研究其对炎症细胞因子表达的调控作用并在HEK293T细胞及香鱼头肾MO/MΦ中研究PaSYK对MAPK信号通路的活化作用。多重序列比对结果显示,SYK的蛋白质序列和结构域在进化过程中是高度保守的。系统进化树结果表明, PaSYK与河鳟的亲缘关系密切。RT-qPCR结果表明, SYK基因mRNA在检测的所有组织中均有表达,鳗弧菌感染后免疫相关组织中PaSYK表达量均上调。此外,PaSYK能显著诱导香鱼头肾MO/MΦ中促炎因子TNF-α和IL-1β的表达,但对抑炎因子TGF-β和IL-10的表达起到略微的抑制作用。Western blot结果证明PaSYK可以激活MAPK信号通路。综上所述, SYK分子在进化上高度保守,香鱼SYK与其哺乳动物中的同源物具有保守的功能,均能活化MAPK信号通路并在炎症反应中发挥作用。  相似文献   

上海中心城就业中心体系测度————基于手机信令数据的研究   总被引：17，自引：2，他引：15  

丁亮  钮心毅  宋小冬 《地理学报》2016,71(3):484-499

利用手机信令数据识别上海市域内手机用户的工作地和居住地,获取就业者的通勤数据,测度上海中心城的就业中心体系.首先用就业者工作地数据生成就业密度分布图,基于中心城的就业密度识别就业中心.随后,用就业者工作地和居住地数据分别从就业密度和通勤联系两方面测度各中心的能级,分析各中心的腹地和势力范围.研究发现:① 上海中心城的就业中心呈主中心强大的弱多中心体系;② 就业密度越高的中心与其他地区的通勤联系一般也越强,但通勤联系在各中心间的差异更显著;③ 能级越高的中心腹地面积越大,但势力范围不一定越大;④ 相比于能级,职住功能混合度对职住平衡的影响更大;⑤缺少就业中心的地区势力范围呈交替状.本研究一定程度上能有助于解决既往就业中心体系研究因空间单元较大,缺少通勤数据在中心识别,通勤联系测度等方面受到的局限,希望能为构建上海中心城就业多中心体系提供帮助.  相似文献