Antioxidation activities of low-molecular-weight gelatin hydrolysate isolated from the sea cucumber <Emphasis Type="Italic">Stichopus japonicus</Emphasis>   总被引：1，自引：0，他引：1  

Jingfeng Wang  Yuming Wang  Qingjuan Tang  Yi Wang  Yaoguang Chang  Qin Zhao  Changhu Xue 《中国海洋大学学报(英文版)》2010,9(1):94-98

Gelatin extracted from the body wall of the sea cucumber (Stichopus japonicus) was hydrolyzed with flavourzyme. Low-molecular-weight gelatin hydrolysate (LMW-GH) of 700–1700 Da was produced using an ultrafiltration membrane bioreactor system. Chemiluminescence analysis revealed that LMW-GH scavenges high free radicals in a concentration-dependent manner; IC₅₀ value for superoxide and hydroxyl radicals was 442 and 285 μg mL⁻¹, respectively. LMW-GH exhibited excellent inhibitory characteristics against melanin synthesis and tyrosinase activity in B16 cells. Furthermore, LMW-GH notably increased intracellular glutathione (GSH), which in turn suppressed melanogenesis. LMW-GH performs antioxidation activity, holding the potential of being used as a valuable ingredient in function foods, cosmetics and pharmaceuticals or nutriceuticals.  相似文献   

Antioxidation Activities of Low-Molecular-Weight Gelatin Hydrolysate Isolated from the Sea Cucumber Stichop us japo nic us     

WANG Jingfeng  WANG Yuming  TANG Qingjuan  WANG Yi  CHANG Yaoguang  ZHAO Qin  XUE Changhu 《青岛海洋大学学报(英文版)》2010,(1):94-98

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