Use of suppressive subtractive hybridization and cDNA arrays to discover patterns of altered gene expression in the liver of dihydrotestosterone and 11-ketotestosterone exposed adult male largemouth bass (Micropterus salmoides)     

Blum JL  Knoebl I  Larkin P  Kroll KJ  Denslow ND 《Marine environmental research》2004,58(2-5):565-569

In this study male largemouth bass (LMB) were exposed to the naturally occurring androgens, dihydrotestosterone (DHT) or 11-ketotestosterone (11-KT) in order to identify genes that are differentially regulated by these steroid hormones. Using subtractive hybridization on livers of fish treated with DHT against vehicle control, many novel LMB genes were cloned. These genes were added to our gene library and arrayed. Six genes were up-regulated and five were down-regulated by both androgens. But, each androgen also regulated specific genes. One gene that was identified as a potential androgen marker was spermidine-spermine-N(1)-acetyltransferase that was up-regulated by both androgens. Determining which genes are responsive to natural androgens will help to identify biochemical pathways that are impacted.  相似文献   

甘肃巴谢剖面黄土-古土壤的光释光测年研究   总被引：2，自引：0，他引：2  

陈杰  卢演俦  尹功明  刘爱国  孙瑛杰  胡碧茹 《地球学报》1997,18(Z1):239-241

光释光（OSL）测年是测定第四纪沉积物年龄的一种新技术。它通过单色光束激发使晶体中储存的电离辐射能释放出来。与热释光（TL）测年相比，OSL测年可以不考虑残留的OSL信号，而且测量具有简便、迅速且准确等优点。本文用细颗粒光释光技术对甘肃巴谢剖面的黄土-古土壤进行了测定，其测年结果与14C测年结果相吻合。这表明，光释光是一项极潜力的年代学技术。  相似文献   

落潮—冰海三角洲周期沉积纹层的形成机理     

Smith  ND 吴智勇 《地质科学译丛》1991,8(1):27-31

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裂变径迹测年     

Naes.  ND 刘爱国 《地震地质译丛》1994,16(4):19-25

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第四纪时期地壳块体相对运动的古地磁记录的初步研究—以陇西和鄂…   总被引：3，自引：0，他引：3  

刘爱国  丁国瑜 《地震地质》1995,17(4):397-404

为了探讨用古地磁方法确定第四纪时期地壳块体相对运动状况，选择了分别处于陇西块体和鄂尔多斯块体内的兰州九州台和陕西洛川两个黄土剖面作为实验对象，在这两个黄土剖面的４个相同年代的层位采集定向大样，作黄土沉积剩余磁化矢量测量，并用虚磁极法拟合，初步结果表明，约１１０万ａ来陇西块体相对于鄂尔多斯块体作顺时针旋转，其转动量达９．０±４．７°。  相似文献   

第四纪时期地壳块体相对运动的古地磁记录的初步研究─-以陇西和鄂尔多斯块体相对运动为例   总被引：2，自引：0，他引：2  

刘爱国  卢演俦  丁国瑜 《地震地质》1995,17(4):397

为了探讨用古地磁方法确定第四纪时期地壳块体相对运动状况，选择了分别处于陇西块体和鄂尔多斯块体内的兰州九州台和陕西洛川两个黄土剖面作为实验对象。在这两个黄土剖面的４个相同年代的层位采集定向大样，作黄土沉积剩余磁化矢量测量，并用虚磁极法拟合，初步结果表明，约１１０万ａ来陇西块体相对于鄂尔多斯块体作顺时针旋转，其转动量达９．０±４．７°  相似文献   

顾及气象和地形元素确定折光系数     

Hop  ND 薄志鹏 《武测译文》1996,(1):19-24

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中地壳流动吗     

撤切尔  刘爱国 《地震科技情报》1993,(5):31-33

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Marine habitats: loss and gain, mitigation and compensation     

Elliott M  Cutts ND 《Marine pollution bulletin》2004,49(9-10):671-674

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Induction of zona radiata and vitellogenin genes in estradiol and nonylphenol exposed male sheepshead minnows (Cyprinodon variegatus)   总被引：1，自引：0，他引：1  

Knoebl I  Hemmer MJ  Denslow ND 《Marine environmental research》2004,58(2-5):547-551

Several genes normally induced by estradiol (E(2)) in female fish, those for vitellogenins (VTGs) and zona radiata proteins (ZRPs), are also inducible in males exposed to estrogenic chemicals. Male sheepshead minnows (SHM) were exposed to both E(2) and para-nonylphenol (NP), at several doses and times to determine a dose-response. Quantitative real time PCR was used to measure mRNA for VTG1, VTG2, ZRP2 and ZRP3. Both E(2) and NP elicited a dose-response increase in all of the mRNAs tested. Exposure to both chemicals resulted in VTG2 expression at about a 10-fold lower level than VTG1, and ZRP2 expression at a lower level than ZRP3.  相似文献