This paper examines community-based water supply management (CBWSM) in three rural districts of Northwest Cameroon as well as a review of the literature focusing on some successful community-based natural resource management initiatives in sub-Saharan Africa. Using empirical and secondary data collected through participatory research methods, it is argued that CBWSM has failed to achieve sustainable water supplies in Northwest Cameroon. Findings revealed that centralized control, the prevalence of poverty, passive involvement of public, private and grassroots community has continued to thwart water supplies within these districts. It is important to note that in any natural resource management system, power becomes a crucial factor as it determines who has and does not have access to common-pool resources. This paper argues that argues that strong traditional leadership, resolute devolution, and active participation of rural communities will facilitate and invigorate a platform for capturing the views of diverse user groups and this can bring about a people-centered and community-driven development process. Some aspects of best practice arising from successful case studies in Cameroon can contribute significantly to promoting the development of effective CBWSM in other rural communities with similar characteristics in and out of Cameroon. This will be possible only if rural groups are involved and engaged in the management of their resources while integrating some aspects of best practice.