排序方式： 共有23条查询结果，搜索用时 542 毫秒
1.
Newark Bay (NB) killifish (Fundulus heteroclitus) have been chronically exposed to environmental contaminants that activate the aryl hydrocarbon receptor (AHR) and are tolerant to toxic effects and CYP1A induction provoked by AHR ligands. Resistance to CYP1A induction could be due to an epigenetic mechanism such as DNA methylation. We measured in-ovo CYP1A catalytic activity (ethoxyresorufin-O-deethylase, EROD) in NB and reference site killifish embryos aqueously exposed to various concentrations of the de-methylating agent 5-azacytidine, 5-AC (5, 50 and 500 μ(micro)M) with or without 0.2 μ(micro)g/l of the CYP1A inducer 3,3′,4,4′,5 pentachlorobiphenyl (IUPAC PCB126). Neither PCB126 alone, nor PCB126 plus 5-AC, induced EROD above levels in vehicle treated Newark Bay fish. In reference site fish, the same PCB126 dose provoked a 7.4-fold EROD induction relative to controls. We conclude that Newark Bay killifish are resistant to CYP1A induction by co-planar PCBs during early embryological development and our data suggests that DNA methylation does not play a critical role in resistance to CYP1A induction in this model. 相似文献
2.
A 2-D time-dependent finite-difference numerical model is used to investigate the thermal character and evolution of a convecting layer which is cooling as it convects. Two basic cooling modes are considered: in the first, both upper and lower boundaries are cooled at the same rate, while maintaining the same temperature difference across the layer; in the second, the lower boundary temperature decreases with time while the upper boundary temperature is fixed at 0°C. The first cooling mode simulates the effects of internal heating while the second simulates planetary cooling as mantle convection extracts heat from, and thereby cools, the Earth's core. The mathematical analogue between the effects of cooling and internal heating is verified for finite-amplitude convection. It is found that after an initial transient period the central core of a steady but vigorous convection cell cools at a constant rate which is governed by the rate of cooling of the boundaries and the viscosity structure of the layer. For upper-mantle models the transient stage lasts for about 30 per cent of the age of the Earth, while for the whole mantle it lasts for longer than the age of the Earth. Consequently, in our models the bulk cooling of the mantle lags behind the cooling of the core-mantle boundary. Models with temperature-dependent viscosity are found to cool in the same manner as models with depth-dependent viscosity; the rate of cooling is controlled primarily by the horizontally averaged variation of viscosity with depth. If the Earth's mantle cools in a similar fashion, secular cooling of the planet may be insensitive to lateral variations of viscosity. 相似文献
3.
A key question in understanding life on Mars under dry(ing) conditions is how arid soils respond to small levels of liquid water. We have conducted a series of simulated rain experiments in the hyperarid core region of the Atacama Desert. Rain amounts from 0.24 to 3.55 mm were applied in the early evening to the soil. We conclude that rain events of less than 1 mm do not saturate the surface, and the soil humidity at the surface remains below 100%. Rain events of 2 mm or more generate free water in the pore space of the soil surface, which may be necessary to support biological activity in the soil. The crust on the surface of the soil is a strong barrier to the diffusion of subsurface moisture and subsequent evaporation. Our results show that once the relative humidity in hyperarid soils begins to fall below 100% the rate of decrease is quite rapid. Thus, the precise value assumed for the limits of life or water activity, do not appreciably change the time of water availability resulting from small desert rains. The Atacama Desert results may be applied to models of (H2O) wetting in the upper soils of Mars due to light rains, melting snow and heavy precipitating fog. 相似文献
4.
The paper presents the problem of a simulation of the greenhouse gases emission permits market where only low accuracy emission amounts are known. An organization of the market with uncertain emissions is proposed and trading rules for individual market participants are discussed. Simulation of the market is based on a multi-agent system. Negotiation of purchase/sale prices between the parties are introduced, where the trading parties adopt one of two options: (i) bilateral negotiations, and (ii) sealed bid reverse auctions. Results of simulation runs show trajectories of transaction prices, as well as probability distributions of learning agents’ bidding prices. 相似文献
5.
In this paper we consider the buying/selling prices of carbon dioxide (CO2) emission permits in trading models with uncertainty. Permission prices, although usually omitted from standard models, may significantly influence the trading market. We thus undertook to construct a more realistic trade model and to compare it with the standard one. To do this, we introduced several important changes to the standard model, namely, (1) a new optimized quality function; and (2) transactions with price negotiations between regions. We also enhanced the model using methods described in the literature to allow it to deal with reported emissions uncertainty. Additionally, we used an original method of simulating this kind of market based on a specialized evolutionary algorithm (EA). 相似文献
6.
The paper describes the results of research on the applicability of the ground penetrating radar (GPR) method for remote sensing and monitoring of the underground coal gasification (UCG) processes. The gasification of coal in a bed entails various technological problems and poses risks to the environment. Therefore, in parallel with research on coal gasification technologies, it is necessary to develop techniques for remote sensing of the process environment. One such technique may be the radar method, which allows imaging of regions of mass loss (voids, fissures) in coal during and after carrying out a gasification process in the bed. The paper describes two research experiments. The first one was carried out on a large-scale model constructed on the surface. It simulated a coal seam in natural geological conditions. A second experiment was performed in a shallow coal deposit maintained in a disused mine and kept accessible for research purposes. Tests performed in the laboratory and in situ conditions showed that the method provides valuable data for assessing and monitoring gasification surfaces in the UCG processes. The advantage of the GPR method is its high resolution and the possibility of determining the spatial shape of various zones and forms created in the coal by the gasification process. 相似文献
7.
8.
The paper describes results of microgravity measurements made on the surface over an underground geo reactor where experimental coal gasification was performed in a shallow seam of coal. The aim of the research was to determine whether, and to what extent, the microgravity method can be used to detect and image a coal gasification zone, especially caverns where the coal was burnt out. In theory, the effects of coal gasification process create caverns and cracks, e.g., zones of altered bulk density. Before the measurements, theoretical density models of completely and partially gasified coal were analysed. Results of the calculations of gravity field response showed that in both cases on the surface over the gasification zone there should be local gravimetric anomalies. Over the geo reactor, two series of gravimetric measurements prior to and after gasification were conducted. Comparison of the results of two measurement series revealed the presence of gravimetric anomalies that could be related to the cavern formation process. Data from these measurements were used to verify theoretical models. After the experiment, a small cavern was detected at the depth of the coal seam by the test borehole drilled in one of the anomalous areas. 相似文献
9.
C. P. C. David Y. Y. Sta. Maria F. P. Siringan J. M. Reotita P. B. Zamora C. L. Villanoy E. Z. Sombrito R. V. Azanza 《Environmental Geology》2009,58(2):447-454
The supply of nitrogen and phosphorus in coastal zones through time is reflected in the nutrients’ concentration in the sediment
record. Five aquaculture sites in the Philippines were investigated in an effort to establish how long-term changes in land
and coastal water use could have led to biogeochemical modifications affecting the coastal ecosystem. Samples from study sites
show a narrow concentration range for nitrogen and did not reveal any significant trend through time. In contrast, phosphorus
concentrations in most sites start at less than 20 ppm in sediments 30 years and older. The phosphorus value continuously
increase in younger sediments, with each site having a different magnitude change as well as timing of when the major increase
happened. The uppermost 10 cm, representing the last 15 years in sites with age control, typically show a 2- to 3-fold increase
in P load values. Historical increase in nutrient load also coincides with harmful algal bloom events in each area; when effective
P input exceeded 130 kg/km2 per year. Lastly, the observed increase may be attributed to several factors including physical attributes of the area, urbanization
of coastal zones, but most importantly in the proliferation of aquaculture activities. 相似文献
10.
Janusz Sylwester Zbigniew Kordylewski Stefan Płocieniak Marek Siarkowski Mirosław Kowaliński Stanisław Nowak Witold Trzebiński Marek Śtęślicki Barbara Sylwester Eugeniusz Stańczyk Ryszard Zawerbny Żaneta Szaforz Kenneth J. H. Phillips František Fárník Anatolyi Stepanov 《Solar physics》2015,290(12):3683-3697