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An active substance, shedding hormone capable of inducing parent clams to spawn and sper-miate, has preliminarily been isolated from the ovaries of Ruditapes philippinarum by means of ammonia sulfate precipitate of 25% concentration and Sephadex G-25 column chromatography in present study. The biological activity of the shedding hormone is above 95%. It is composed of sorts of amino acids by determination with an amino acid automatic analyzer. The experimental results indicate that the active substance is a polypeptide.  相似文献   
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