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1.
The short-term effects of the commercial PBDE flame retardant mixtures Penta-BDE and cta-BDE on the expression of cytochrome P450 1A (CYP1A), vitellogenin (Vtg) and zona radiata proteins (Zrp) were investigated in juvenile salmon (Salmo salar). For this purpose, groups of fish were dosed twice (oral intake at days I and 4) with 10 and 50 mg/kg body weight of both commercial mixtures. The fishes were sacrificed at day 7 (n = 5 for each group) and 14 (n = 6 for each group), and blood, liver, fillet, and brain were collected. Blanks and positive controls were also part of the experiment. The expressions of Vtg, Zrp, and CYPIA were measured with several techniques (EROD, ELISA, Western, Northern and Slot Blot). The values in the groups of fish treated with Penta-BDE or Octa-BDE did not significantly differ from the reference group for any of the parameters tested. In contrast, the positive control groups treated with estradiol-17beta for Vtg and Zrp expression, and beta-naphthoflavone for CYP1A expression did show a significant response, indicating the potential sensitivity of the fishes for the parameters measured. Since the results of the chemical analyses showed concentrations of a number of PBDE congeners in liver, fillet, and brain that were about three orders of magnitude above those of fish from the North Sea, it is concluded that the short-term toxicity of both commercial PBDE mixtures for these endpoints was low.  相似文献   
2.
The primary goals of seismic interpretation and quantification are to understand and define reservoir architecture and the distribution of petrophysical properties. Since seismic interpretation is associated with major uncertainties, outcrop analogues are used to support and improve the resulting conceptual models. In this study, the Miocene carbonates of Cerro de la Molata (Las Negras, south‐east Spain) have been selected as an outcrop analogue. The heterogeneous carbonate rocks of the Cerro de la Molata Platform were formed by a variety of carbonate‐producing factories, resulting in various platform morphologies and a wide range of physical properties. Based on textural (thin sections) and petrophysical (porosity, density, carbonate content and acoustic properties) analyses of the sediments, eleven individual facies types were determined. The data were used to produce synthetic seismic profiles of the outcrop. The profiles demonstrate that the spatial distribution of the facies and the linked petrophysical properties are of key importance in the appearance of the synthetic seismic sections. They reveal that carbonate factory and facies‐specific reflection patterns are determined by porosity contrasts, diagenetic modifications and the input of non‐carbonate sediment. The reflectors of the seismograms created with high‐frequency wavelets are coherent with the spatial distribution of the predefined facies within the depositional sequences. The synthetic seismograms resulting from convolution with lower frequency wavelets do not show these details – the major reflectors coincide with: (i) the boundary between the volcanic basement and the overlying carbonates; (ii) the platform geometries related to changes in carbonate factories, thus sequence boundaries; and (iii) diagenetic zones. Changes in seismic response related to diagenesis, switching carbonate producers and linked platform geometries are important findings that need to be considered when interpreting seismic data sets.  相似文献   
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The short-term effects of the commercial PBDE flame retardant mixtures Penta-BDE and Octa-BDE on the expression of cytochrome P450 1A (CYP1A), vitellogenin (Vtg) and zona radiata proteins (Zrp) were investigated in juvenile salmon (Salmo salar). For this purpose, groups of fish were dosed twice (oral intake at days 1 and 4) with 10 and 50 mg/kg body weight of both commercial mixtures. The fishes were sacrificed at day 7 (n=5 for each group) and 14 (n=6 for each group), and blood, liver, fillet, and brain were collected. Blanks and positive controls were also part of the experiment. The expressions of Vtg, Zrp, and CYP1A were measured with several techniques (EROD, ELISA, Western, Northern and Slot Blot). The values in the groups of fish treated with Penta-BDE or Octa-BDE did not significantly differ from the reference group for any of the parameters tested. In contrast, the positive control groups treated with estradiol-17β for Vtg and Zrp expression, and β-naphthoflavone for CYP1A expression did show a significant response, indicating the potential sensitivity of the fishes for the parameters measured. Since the results of the chemical analyses showed concentrations of a number of PBDE congeners in liver, fillet, and brain that were about three orders of magnitude above those of fish from the North Sea, it is concluded that the short-term toxicity of both commercial PBDE mixtures for these endpoints was low.  相似文献   
6.
可持续发展背景下区域旅游业竞争力评价研究   总被引:1,自引:0,他引:1  
如何评价区域旅游业竞争力水平是区域旅游业进行旅游规划和提高竞争力水平的基础和出发点.在可持续发展背景下以竞争力理论、旅游系统理论等为依据,从旅游业基础竞争力、竞争业绩、竞争潜力3个层面构建了区域旅游业竞争力评价指标体系,运用层次分析法来确定指标权重,在此基础上以我国30个省级行政区为研究对象进行了应用,对我国区域旅游业竞争力水平进行了较为深入的分析.提出的指标体系和层次分析法可以为区域旅游业竞争力研究提供一定的借鉴.  相似文献   
7.
While the existence of relatively fresh groundwater sequestered within permeable, porous sediments beneath the Atlantic continental shelf of North and South America has been known for some time, these waters have never been assessed as a potential resource. This fresh water was likely emplaced during Pleistocene sea-level low stands when the shelf was exposed to meteoric recharge and by elevated recharge in areas overrun by the Laurentide ice sheet at high latitudes. To test this hypothesis, we present results from a high-resolution paleohydrologic model of groundwater flow, heat and solute transport, ice sheet loading, and sea level fluctuations for the continental shelf from New Jersey to Maine over the last 2 million years. Our analysis suggests that the presence of fresh to brackish water within shallow Miocene sands more than 100 km offshore of New Jersey was facilitated by discharge of submarine springs along Baltimore and Hudson Canyons where these shallow aquifers crop out. Recharge rates four times modern levels were computed for portions of New England's continental shelf that were overrun by the Laurentide ice sheet during the last glacial maximum. We estimate the volume of emplaced Pleistocene continental shelf fresh water (less than 1 ppt) to be 1300 km3 in New England. We also present estimates of continental shelf fresh water resources for the U.S. Atlantic eastern seaboard (104 km3) and passive margins globally (3 × 105 km3). The simulation results support the hypothesis that offshore fresh water is a potentially valuable, albeit nonrenewable resource for coastal megacities faced with growing water shortages.  相似文献   
8.
The legislative framework for the environmental protection of the North Sea has developed extensively during the past two decades. This framework includes proposals within national, regional, European and global initiatives. This paper describes the development of the Oslo and Paris Commissions and their relationship with the North Sea Ministerial Conferences. The new OSPAR Convention, signed in Paris in 1992, is described as a model for protection frameworks for other regional seas.  相似文献   
9.
Zegers  de Wit  Dann  & White 《地学学报》1998,10(5):250-259
The only remaining areas of pristine 3.6–2.7 Ga crust on Earth are parts of the Kaapvaal and Pilbara cratons. General similarities of their rock records, especially of the overlying late Archean sequences, suggest that they were once part of a larger Vaalbara supercontinent. Here we show that the present geochronological, structural and palaeomagnetic data support such a Vaalbara model at least as far back as 3.1 Ga, and possibly further back to 3.6 Ga. Vaalbara fragmented prior to 2.1 Ga, and possibly as early as 2.7 Ga, suggesting supercontinent stability of at least 400 Myr, consistent with Neoproterozoic and Phanerozoic analogues.  相似文献   
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