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Evaluation of mouse bioassay results in an inter-laboratory comparison for paralytic shellfish poisoning toxins 总被引：1，自引：0，他引：1
An inter-laboratory comparison of the AOAC mouse bioassay for paralytic shellfish poisoning (PSP) toxicity in shellfish was carried out among 25 Chinese laboratories to examine the overall performance for PSP testing in China, and to analyze the main factors affecting the performance of this method. The toxic scallop Patinopecten yessoensis collected from coast of Bohai Sea, China, was used as a test sample in the comparison study. The results were reported and evaluated using robust statistical methods. The z scores showed that 80%, 8%, and 12% of laboratories reported satisfactory results, unsatisfactory results, and questionable results, respectively. This evaluation demonstrates that the PSP mouse bioassay is an appropriate method for screening and testing PSP toxicity in shellfish. However, it was found that the experience and skill of technicians, as well as the body weight and health status of mice being used significantly affected the accuracy of the method. 相似文献
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云的形成过程及其类型复杂多样,在气候系统中发挥着重要作用.在当前气候背景下,云在大气顶的净辐射效应为负值,即对地气系统起着强烈的冷却作用.云反馈过程是当前气候变化研究中不确定性最大的因子之一,其强度会随时间、空间、云量、云高、云光学厚度等发生变化.目前,观测研究和气候模拟都表示全球平均云反馈为正值,以热带高云高度反馈和热带海洋低云量反馈两个正反馈为主,但是云反馈仍然存在较大的不确定性.在温室气体驱动的全球变暖下云如何对气候系统进行反馈至关重要,它直接影响气候敏感度的估算并决定着气候模式对未来全球变暖预估的准确性.因此,云反馈强度也会在很大程度上影响温室气体减排政策的制定.为此,本文回顾了云在气候系统中反馈作用的最新研究进展,指出了该研究领域当前面临的关键挑战,最后,对未来需要开展的研究进行了讨论与展望,以期为全球和东亚区域云辐射物理过程模拟、模式不确定性分析以及未来气候变化和全球变暖预估等方面的研究提供系统的科学参考. 相似文献
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