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The use of antidepressants is widespread in modern times. Thus, they present a potential risk for ecosystems due to occurrence in domestic sewage containing unaltered metabolites and structures, even after the treatment plants have processed the sewage. The current research investigated the sorption and desorption of antidepressants(citalopram, venlafaxine, fluoxetine, sertraline, and amitriptyline) and caffeine from freshwater sediment and sewage sludge. The samples of freshwater sediment were ...  相似文献   
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Adolescent drug use is individually and socially harmful in terms of disrupting adolescent development and social cohesion. Prior research has identified populations at risk and risk factors for adolescent drug use. This research sought to contextualize adolescent drug use by examining this behavior from a geographic perspective. The specific objectives were to identify patterns, local clusters and excess spatial risk for 5-digit zip codes within the 5-county Cincinnati, Ohio region. Adolescents (n = 57,241) were recruited within local schools by the Coalition for a Drug-free Greater Cincinnati. Results of this research show spatial clusters for perceived safety of marijuana; peer approval of alcohol, tobacco and marijuana; and age of onset for other drugs. The location and nature of these clusters are discussed and displayed in-text. Further, zip codes that were in excess risk compared to the 5-county region were identified. The utility of this research is two-fold: (1) It identifies the geographic variability in adolescent drug use and correlated factors of use, and (2) It provides a methodological framework for future research in spatial epidemiology of drug use.  相似文献   
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Examination of the Degradation of Drugs in Municipal Sewage Plants Using Liquid Chromatography-Electrospray Mass Spectrometry Numerous drugs can be identified in the secondary effluent of municipal sewage plants. In order to obtain information about the degree of elimination (adsorption, aerobic degradation) of these compounds, a batch reactor containing different drugs in environmentally relevant concentrations and a suspension of activated sludge was coupled to a HPLC-MS-MS system. During a testing period of three days concentration-time-curves were recorded. For most of the examined drugs (acetamidoantipyrine, crotamiton, diclofenac, primidone, propyphenazone) solely a strong decrease of the initial concentration within the first 15 minutes was observed, which was interpreted primarily as adsorption to the activated sludge. For acetaminophenol and pentoxifyllin an additional slower decrease in concentration within several hours was observed. This slower elimination was interpreted to be caused mainly by primary degradation. It could be shown that dihydrocodeine is oxidized to hydrocodone in the batch reactor. The conjugate acetaminophen glucuronide was cleaved.  相似文献   
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环境因子及药物对牙鲆盾纤类纤毛虫病病原纤毛虫的影响   总被引:5,自引:0,他引:5  
报道了牙鲆寄生盾纤类纤毛虫病病原形态,温度,盐度、pH值对病原纤毛虫的影响,药物筛选,试验结果表明,该纤毛虫适宜生长的温度为15 ̄20℃、盐度30 ̄35‰,pH值4-6。外用药如:福尔马林,高锰酸钾,卤素类消毒剂以及淡水支该纤毛虫有较好的杀灭作用。  相似文献   
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