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Least squares estimation (LSE) is theoretically related to quadratic unbiased estimation of variance components. It is argued that these methods of estimation of variance components essentially generalize LSE though they are not formally equivalent.  相似文献   
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This article illustrates the use of linear and nonlinear regression models to obtain quadratic estimates of covariance parameters. These models lead to new insights into the motivation behind estimation methods, the relationships between different methods, and the relationship of covariance estimation to prediction. In particular, we derive the standard estimating equations for minimum norm quadratic unbiased translation invariant estimates (MINQUEs) from an appropriate linear model. Connections between the linear model, minimum variance quadratic unbiased translation invariant estimates (MIVQUEs), and MINQUEs are examined and we provide a minimum norm justification for the use of one-step normal theory maximum likelihood estimates. A nonlinear regression model is used to define MINQUEs for nonlinear covariance structures and obtain REML estimates. Finally, the equivalence of predictions under various models is examined when covariance parameters are estimated. In particular, we establish that when using MINQUE, iterative MINQUE, or restricted maximum likelihood (REML) estimates, the choice between a stationary covariance function and an intrinsically stationary semivariogram is irrelevant to predictions and estimated prediction variances.  相似文献   
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