双因素判别分析胃癌组织与正常组织自体荧光光谱     

马君  史晓凤  李颖  王荣  毛伟征  郑荣儿  孟继武 《中国海洋大学学报(自然科学版)》2004,34(4):662-666

通过对手术切除的37例胃癌患者的离体标本的自体荧光光谱检测,显示308nm,337nm激发光谱均呈双主峰结构,双主峰的比值均能区分胃癌与正常胃壁(P<0.001).分别用308nm,337nm激发荧光光谱单因素分析诊断胃癌的灵敏度、特异度、阳性预测值分别为88.8%,86.8%,86.4%和80.1%,72.1%,67.5%.对308nm及337nm激发荧光光谱双因素分析,癌诊断的灵敏度、特异度、阳性预测值分别为94.4%,92.1%,91.9%,其诊断正确符合率明显高于单因素分析的结果.研究表明,以308nm及337nm双波长激发检测胃壁浆膜,双因素判别算法可较好地区分胃癌,这种方法有望成为手术中快速识别胃癌在胃壁的浸润范围的有效方法.  相似文献   

Elements pollution in the extremely high tumor risk residents in Chaoshan littoral, southern China     

Min SU Min LIU Dongping TIAN Guohong ZHANG Liangli HONG Yuxia GAO 《中国地球化学学报》2006,25(B08):61-61

Background ＆ aim： To investigate and analyze the elements pollution in the extremely high tumor risks residents in the Chaoshan littoral, southern China. Methods： 19 elements including Cr, Mn, Ni, Sr, Pb, Zn, Co, Sn, Th, Tl, Se, Hg, Cu, Mo, Cd, Sb, U, Ge, As, and Al were measured from 145 hair samples of residents from the high-risk Nanao Island （mortality of cancer 173-156/106 in recent 30 years）, Shantou high-risk village （mortality of cancer 230.4/106 in recent three years）, and two controls Shanwei （mortality of cancer 32/106 in 1970s） and Meizhou Hakka （incidence of cancer 103/106 ） using AAS, AFS, ICP-MS methods collaborated with Beijing University. And 21 samples of water, 18 samples office from the Nanao Island, Shantou high-risk village, and other low-risk controls were measured using the same methods. Results： The element analysis showed that levels of CD, PB in the Shantou high-risk village were the highest, Hg, MN, SR, SB, TH, U on the Nanao Island were the highest in hairs. Conclusions： It is indicated that there occurred elements pollution among the local high-risk population.  相似文献   

肝硬化再生结节病的CT诊断与鉴别   总被引：1，自引：1，他引：1  

黄绍权 《CT理论与应用研究》2002,11(1):34-35

本文目的是探讨肝硬化再生结节的CT诊断及鉴别，提高肝内结节的诊断水平。方法：对120例肝硬化再生结节的CT平扫及增强图象的分析。结果：肝硬化再生结节以圆形为主，直径在5mm－55mm之间，平扫多数呈高密度，结节的分布据结节的分型而定。结论：明确肝硬化再生结节的CT诊断依据及与肝癌、肝血管瘤的鉴别。  相似文献   

Radon,Lung Cancer Risk and Environmental Geology in Gejiu Area     

卢伟  王任重等 《中国地球化学学报》1997,16(3):278-282

The incidence of lung cancer in the Gejiu area of Yunnan Province ranks the first in the world.The radon level(indoor,soil) was measured in the Gejiu area by the SSNTD method from 1990 to 1996,The result indicates an extensive high-level of indoor radon in that area though U and Th are lower in local limestones,The indoor radon level of houses located in the geologic fault zone is 6 times high that 2km far from the fault zone.The reason probably is that the radon level of soil in the fault is 6-8 times high that 1 km far from the faults.our data indicate that a lower range of radon levels,0-100Bq.m^-3,exists in healthy families.However,a higher radon level,over 800 Bq.m^-3,is often found corresponding to that of cancer patients‘ homes(the house-owners are suffering from either lung cancer or leukaemia or liver cancer),Obviously,an increase in lung cancer incidence follows an increase in indoor radon level,The risk of cancer induced by indoor radon is no longer an inference,but a fact.  相似文献   

外围性小肺癌的CT诊断     

唐桂长  房桂云 《CT理论与应用研究》1994,3(3):36-41

作者报告了４０例外围性小肺癌。并对≤３ｃｍ的外围性小肺癌的ＣＴ征象进行了讨论和总结。作者认为：小结节征、分叶征、棘状突、空泡征、胸膜凹陷等征象，对外围性小肺癌有诊断价值。  相似文献   

Modelling and predicting the spatial dispersion of skin cancer considering environmental and socio-economic factors using a digital earth approach     

Zohreh Masoumi  John L. van Genderen  Mohammad Sadi Mesgari 《International Journal of Digital Earth》2020,13(6):661-682

ABSTRACT

Almost all causative factors of diseases depend on location. The Digital Earth approach is suitable for studying diseases globally. Geospatial information systems integrated with statistical models can be used to model the relationship between a disease and its causative factors. Through modelling, the most important causative factors can be extracted and the epidemiology of the disease can be observed. In this paper, skin cancer (the most common type of cancer) has been modelled based on its causative factors, including climate factors, people's occupations, nutrition habits, socio-economic factors, and usage of chemical fertiliser. To fit the model, a data framework was first designed, and then data were gathered and processed. Finally, the disease was modelled using Generalised Linear Models (GLM), a statistical model based on the location of the factors. The results of this study identify the most important causative factors together with their relative priority. Furthermore, a model was used to predict the change in skin cancer occurrences caused by a change in one of its causative factors. This work illustrates the ability of the model to predict disease occurrence. Thus, by using this Digital Earth approach, skincancer can be studied in all the key countries around the world.  相似文献   

Proterozoic fluvial styles: response to changes in accommodation space (Rivieradal sandstones, eastern North Greenland)     

Martin S  nderholm  Henrik Tirsgaard 《Sedimentary Geology》1998,120(1-4):257-274

Fluvial styles recorded by the uppermost part of the Neoproterozoic ‘Rivieradal sandstones' succession of eastern North Greenland reflect variations in rate of generated accommodation space and possibly climatic changes. Three facies associations, arranged in two genetic sequences, are recognised within the succession. The lower sequence initially records little available accommodation space. A high degree of reworking results in sheet-like, high-energy, bed-load-dominated, braided river deposits lacking recurrent facies patterns. As accommodation space increases upwards through the sequence, reduction in reworking is recorded by the development of fining- and thickening-upward muddy fluvial cycles. Evidence of desiccation or prolonged periods of drought are absent within the deposits and climate was probably relatively humid. Channel deposits in the lower sequence reflect mixed-load, braided fluvial systems with stable channel banks and floodplains, and the gradient appears to have been low to moderate. These features are generally considered favourable for the establishment of meandering river systems, but channels, nevertheless, retained an overall braided character and their deposits show no evidence of meandering. Despite indications of a climatic setting without significant periods of drought sediments indicate that large fluctuations in discharge occurred within the mixed-load streams and this is suggested to be the main cause for the absence of meandering. The swift and rather dramatic response of the fluvial systems to changes in precipitation, probably resulted from rapid runoff rates caused by the absence of vegetation. The upper sequence shows an initial return to shallow, sandy braided river deposition recording little available accommodation space. A subsequent increase in the rate of generated accommodation space is indicated by the presence of alternating sheet sandstones and sand-streaked mudstones with abundant desiccation cracks. The sheet sandstones show evidence of high-energy, unconfined ephemeral fluvial flash-flood deposition, while the mudstones are interpreted to represent muddy floodplain deposits. The change in fluvial style, combined with the widespread evidence of desiccation, suggest an evolution towards a more semi-arid climate in the upper sequence. This climatic change could account for the reduced clastic input seen in the overlying marine succession which culminated in carbonate platform deposition. The present study suggests that even under conditions considered favourable for the formation of meandering streams, these will rarely occur in Proterozoic deposits due to the lacking influence of vegetation. Although meandering deposits cannot be ruled out as having formed in pre-vegetational times, the conditions for their formation appear to have been even more restricted than previously realised.  相似文献   

Controls on spatial and temporal distribution of Precambrian eolianites     

Kenneth A. Eriksson  Edward L. Simpson 《Sedimentary Geology》1998,120(1-4):275-294

Inversely graded stratification, generated by the migration of wind ripples, and adhesion structures permit unequivocal identification of Precambrian eolianites. These criteria, in combination with scale of cross-beds, angle of inclination of foresets, geometry of depositional units, and associated non-eolian facies, are used to discriminate between Precambrian dune/draa, dune-plinth, sand-sheet, and interdune deposits that formed in inland and coastal settings. Based on an analysis of published literature, fundamental conclusions can be drawn on the spatial and temporal distribution of Precambrian eolianites. The oldest reported eolianites are from the ca. 2.1 Ga Deweras Group in Zimbabwe and Hurwitz Group in Canada and numerous examples of eolianites are reported from the 1.8 Ga and younger rock record. Lack of Archean and early Paleoproterozoic eolianites and their widespread development after 1.8 Ga are examined with respect to: absence of vegetation, crustal growth and tectonic setting, relative sea-level fluctuations, unfavorable atmospheric and/or climatic change, and non-recognition. The lack of pre-2.2 Ga eolianites may be related to reworking by braided rivers combing across non-vegetated floodplains, reworking of coastal eolianites during transgression or their non-recognition in the Early Precambrian record. The temporal concentration of eolianites at 1.8 Ga may best be related to the early stages of breakup and the assembly phases of supercontinents.  相似文献   

Preservation of pre-vegetational mixed fluvio–aeolian deposits in a humid climatic setting: an example from the Middle Proterozoic Eriksfjord Formation, Southwest Greenland     

Henrik Tirsgaard  Ingrid E. I. xnevad 《Sedimentary Geology》1998,120(1-4):295-317

Sedimentological studies of a 30 m thick coastal cliff section within the Middle Proterozoic Eriksfjord Formation in western South Greenland reveals three distinct types of fluvial sand sheet deposits that reflect perennial streams (Type I), semi-perennial streams (Type II), and ephemeral flash floods (Type III). Perennial river sand sheets are characterised by co-sets of medium-scale trough cross-beds, interbedded with isolated medium- and large-scale, high-angle, tabular cross-beds. Indications of desiccation or subaerial exposure are absent. Semi-perennial fluvial sand sheets consist predominantly of low-angle cross-beds, interbedded with isolated sets of high-angle tabular cross-beds with common reactivation surfaces. Horizontal lamination and climbing ripple lamination form subordinate structures. Associated with the sand sheets are adhesion structures and 0.05–0.4 m thick sets of wind ripple-lamination indicating periods of subaerial exposure and aeolian reworking. High-energy ephemeral flash flood sand sheets consist almost exclusively of planar-parallel lamination and climbing ripple lamination with some isolated sets of low-angle cross-bedding. Scouring and internal truncation surfaces are common. The three types of sand sheets are considered to reflect deposition under changing climatic conditions, varying from humid to arid or semi-arid. Aeolian deposits are preserved within the sand sheets showing characteristics of dominantly perennial flow punctuated by shorter periods of desiccation (Type II), while sand sheets showing features typical of arid and or semi-arid flow conditions (Type III) contain no preserved aeolian deposits. This selective preservation is interpreted to be a result of the combined effect of groundwater table level and fluvial style which in turn are inferred to have been controlled by the climatic regime. The deposits show that during pre-vegetational times the preservation of aeolian deposits, under certain conditions, may be more optimal in fluvial systems formed in a humid climate than in fluvial systems formed under semi-arid or arid circumstances. The occurrence of aeolian deposits within a Precambrian succession of fluvial deposits therefore, need not be an indication of the most arid environmental conditions.  相似文献   

Precambrian tidal and glacial clastic deposits: implications for Precambrian Earth–Moon dynamics and palaeoclimate     

George E. Williams 《Sedimentary Geology》1998,120(1-4):55-74

Over the past decade the study of Precambrian clastic tidal rhythmites — stacked laminae of sandstone, siltstone and mudstone that display periodic variations in thickness reflecting a strong tidal influence on sedimentation — has provided accurate palaeotidal and palaeorotational data. Palaeotidal records obtained from tidal rhythmites may be systematically abbreviated, however, and derived periods and frequencies can be misleading. The validity of such values, including past length of day, can be assessed by testing for internal self-consistency through application of the laws of celestial mechanics. Such a test supports the estimated length of day of h derived from the late Neoproterozoic (620 Ma) Elatina–Reynella rhythmites in South Australia, and the indicated mean rate of lunar retreat of cm/year since 620 Ma. The validity of estimated lengths of day obtained from other Precambrian tidal rhythmites remain unverified because the data sets contain only one primary value directly determined from the rhythmites. The Elatina–Reynella data militate against significant Earth expansion at least since 620 Ma, and suggest that the free nutation or ‘tipping' of the Earth's fluid core has undergone a resonance with the Earth's annual forced nutation since the Neoproterozoic. Glaciogenic deposits are readily distinguishable from ejecta resulting from impacts with Earth-crossing bodies. Palaeomagnetic data, based on the geocentric axial dipole model for the geomagnetic field, indicate that Neoproterozoic and Palaeoproterozoic glaciation and cold climate near sea level occurred in low palaeolatitudes. This enigmatic finding may imply global glaciation or an increased obliquity of the ecliptic, and is relevant to modelling the effect of ice sheet formation on the Earth's obliquity history by obliquity–oblateness feedback mechanisms. Through multidisciplinary studies, clastic sedimentology and geophysics together can make substantial contributions to understanding Precambrian Earth–Moon dynamics and global palaeoenvironments.  相似文献