Relationship between reference value (Wintrobe) of Chinese people's erythrocyte sedimentation rate (ESR) and geographical factors     

GEMiao  YAN Yan  REN Zhi-yuan  GUO Cai-ling  YUE Da-peng  YIN Shu-yan 《地理学报(英文版)》1999,(2)

IntroductionEothrocytesedimentahonrateusSR)isanimportantindexofhemorheology.Atpresent,itisdifficulttoachieveaccuracyandcomparabilityinclinicalprachceandresearchbecauseoflackofaunifiedstandardofthereferencevalue(Wintrobe)ofhealthyPeople'sESRinChina.ManyresearchershavemeaSUredthelocalreferencevaluesofESR(Wintrobe)l'-:'l.Bymeansofcorrelationandregressionanalysis,researchontherelationshipbetweenthereferencevalue(Wintrobe)ofESRandgeographicalfactorsshowedthathlereareceylonregularPatternsbet…  相似文献   

Study on antithrombotic and antiplatelet activities of low molecular weight fucoidan from Laminaria japonica   总被引：1，自引：0，他引：1  

Anjin Chen  Fang Zhang  Jie Shi  Xue Zhao 《中国海洋大学学报(英文版)》2012,11(2):236-240

The antithrombotic and antiplatelet effects of two fucoidan fractions with low molecular weight and different sulfate content from Laminaria japonica were compared in order to examine the influence of chemical character on their antithrombotic activity and the possible mechanism. Both LMW fucoidan fractions exhibited favorable antithrombotic activity in an Fecl3-induced arterial thrombosis. The antithrombotic activity of LMW fucoidan was related with decrease of TXB2 and whole blood viscosity and hematocrit. LMW fucoidan showed a correlation between anticoagulant, antiaggregant and antithrombotic effects in vivo. For LMW fucoidan, antithrombotic activity required high dose of 5-10 nmol kg-1, concomitantly with increase in anticoagulant activity and inhibition of platelet aggregation. Administration of LMW fucoidan significantly promoted the 6-keto-PGF1α content and decreased the TXB2 content, indicating its inhibition of tissue factor pathway and regulation of metabolism of arachidonic acid. By comparison, highly sulfated fucoidan LF2 with Mw 3900 seemed to be a more suitable choice for antithrombotic drug for its antithrombotic activity accompanied with specific inhibitory activity on platelet aggregation, low anticoagulant activity and low hemorrhagic risk in vivo.  相似文献   

Study on Antithrombotic and Antiplatelet Activities of Low Molecular Weight Fucoidan from Laminariajaponica     

CHEN Anjin  ZHANG Fang  SHI Jie  ZHAO Xue 《青岛海洋大学学报(英文版)》2012,(2):236-240

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基于人工神经网络的老年男性血沉参考值与地理环境关系研究   总被引：4，自引：0，他引：4  

杨青生  张红贤  葛淼  刘燕  姜海艳  葛本伟 《地理科学》2006,26(6):749-754

以健康老年男性血沉参考值为例,收集中国各地用温氏法测定的健康老年男性血沉参考值,运用BP神经网络模拟分析其与地理环境的海拔高度、年日照时数、年平均相对湿度、年平均气温、年降水量等要素间的非线性、复杂性关系特征,通过5层神经网络,经过500次及1 300次自学习建立模拟规则后,用此规则很好地模拟健康老年男性血沉参考值与地理环境的关系。知道中国某地的地理要素, 就可用此模型估算该地区老年男性血沉参考值。人工神经网络预测血沉参考值的模型自动定义具体的结构和参数,减少血沉参考值预测中的人为性,计算方便;同时,通过对不同地理要素的组合,模型可以寻找预测误差最低的地理要素组合关系。  相似文献