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目的：探讨睾丸精原细胞瘤的CT、MRI特点,以提高对本病的认识。方法：回顾性分析有完整CT或MRI平扫及增强资料、经手术及病理证实的13例睾丸精原细胞瘤的影像表现。3例患者行CT检查,10例行MRI检查。结果：13例中有3例为未降睾丸并发精原细胞瘤。睾丸精原细胞瘤CT主要表现为中等均匀密度,增强扫描轻度到中度强化;MRI主要表现为结节状,信号较均匀,T2WI呈稍低信号,可见低信号线状纤维血管分隔,增强时分隔强化,肿瘤实质轻度强化。未降睾丸并精原细胞瘤位于正常睾丸下降路径,可发生于腹膜后、盆腔等部位,病灶体积较大,密度或信号不均,增强扫描明显强化。结论：睾丸精原细胞瘤的CT、MRI表现具有一定的特征性,具有较高的诊断和鉴别价值。 相似文献
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【目的】优化太平洋牡蛎(Crassostreagigas)酶解工艺条件,并研究酶解产物及其超滤组分对体外培养的睾丸间质细胞增殖及睾酮分泌的影响。【方法】以多肽得率为参考标准,对木瓜蛋白酶酶解牡蛎的加酶量、初始pH、酶解时间、酶解温度进行单因素及正交实验优化;通过MTT法及酶联免疫吸附试验(ELISA)检测不同浓度牡蛎酶解产物及其超滤组分对TM3小鼠睾丸间质细胞增殖及睾酮分泌的影响。【结果】木瓜蛋白酶最佳酶解条件为加酶量3 000 U/g,初始pH 6. 5,酶解温度62.5℃,酶解时间4.5 h,在此条件下其多肽质量浓度为14.95 mg/mL;牡蛎酶解液及其超滤组分在0.25～1.00 mg/mL质量浓度范围内,与空白对照组相比,能够显著增加TM3细胞的增殖活性(P0.05),且具有浓度依赖性和时间依赖性。其中,5 ku和5～10 ku超滤组分细胞增殖活性及促进睾酮分泌活性均最强。【结论】牡蛎酶解产物及其超滤组分可有效增强小鼠睾丸间质细胞增殖活性并促进其分泌睾酮。 相似文献
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Boleophthalmus pectinirostris is an amphibious economic fish and wildly distributed in the southeast coast of China. In this study, Aroclor 1254 was intraperitoneally injected into B. pectinirostris with 1, 2 and 4 μg/(g·d) for 28 d to assay the reproductive organ weight, the sperm quality (sperm concentration and motility), and the testicular mitochondrial testicular mitochondria oxidative stress. The results show that the sperm number and motility in seminal vesicles, the absolute weight of testes and seminal vesicles of B. pectinirostris treated with 2 and 4 μg/(g·d) Aroclor 1254 decreased significantly as compared to the controls (p <0.05), while those treated with 1 μg/(g·d) Aroclor 1254 had no significant effects on these indictors. For the relative weight of reproductive organs, significant reduction (p <0.05) was only observed in the seminal vesicles of B. pectinirostris treated with 4 μg/(g·d). SOD activities and GSH levels in all the Aroclor 1254 treatments were significantly lower than those of the controls (p <0.05). The activities of CAT, GPx, GR and the levels of Vit C also decreased significantly in comparison with the controls (p <0.05) at the higher dose of 2 and 4 μg/(g·d) Aroclor 1254 treatments. In addition, both H2O2 level and MDA content in testicular mitochondria of B. pectinirostris had a close correlation with Aroclor 1254 dosage, and were significantly higher than the controls (p <0.05). Those indicate that Aroclor 1254 can induce the oxidative stress of testicular mitochondria, and impair the reproductive function of male B. pectinirostris. 相似文献
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目的:分析睾丸原发肿瘤的CT影像特征.方法:回顾性分析46例经病理证实的睾丸肿瘤CT影像资料,结合其他资料对病灶做综合评估.结果:所有肿瘤均为单侧发病.精原细胞瘤24例,其中16例可见不均匀轻度分隔样强化;内胚窦瘤10例,8例可见多发迂曲、增粗供血血管;畸胎瘤4例,可见斑点状、不规则钙化,2例可见脂肪;混合性生殖细胞肿... 相似文献
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Histological characteristics of gametogenesis of two kinds of scallops, gonochoric Chinese scallop, Chlamys farreri and hermaphroditic bay scallop, Argopecten irradians were investigated in this study. Spermatogenesis in C. farreri has different developmental stages: spermatogonia, primary spermatocyte, second spermatocyte, spermatid and spermatozoon. A large number of same developmental stage spermatic cells converge at a definite area of the testis. Premeiotic, previtellogenic and vitellogenic oocytes can be found during oogenesis in C. farreri, where oocyte distribution is obviously irregular. The A. irradians gonad consists of two different parts in one individual: one part functions as testis, the other as ovary. Between these two parts is a special appearance area, where a large number of spermatic cells are bound with two layers of acellular substance with many oocytes in it. 相似文献
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