| 基于综合生物标志物响应评价苯并芘对脊尾白虾(Exopalaemon carinicauda)的毒性效应 |
| |
| 引用本文： | 李磊,刘金殿,黄士林,唐峰华,陈玉生,赵永超,许呈林,王云龙,沈新强,蒋玫.基于综合生物标志物响应评价苯并芘对脊尾白虾(Exopalaemon carinicauda)的毒性效应[J].海洋与湖沼,2018,49(2):444-451. |
| |
| 作者姓名： | 李磊 刘金殿 黄士林 唐峰华 陈玉生 赵永超 许呈林 王云龙 沈新强 蒋玫 |
| |
| 作者单位： | 农业部淡水渔业健康养殖重点实验室浙江省鱼类健康与营养重点实验室浙江省淡水水产研究所;中国水产科学研究院东海水产研究所;海盐县海洋与渔政管理站;江苏省海洋水产研究所 |
| |
| 基金项目： | 农业部淡水渔业健康养殖重点实验室开放课题，ZJK201509号；上海市科学技术委员会项目，12231203403号；中国水产科学研究院基本科研业务费项目，2014A02XK01号。 |
| |
| 摘 要： | 苯并a]芘(Ba P)是一类典型多环芳烃(PAHs)污染物。为了定量评价Ba P对脊尾白虾(Exopalaemon carinicauda)的毒性效应,采用水体暴露实验,研究了脊尾白虾肝胰脏、肌肉组织的5种生物标志物(EROD、GST、SOD、CAT、MDA)对Ba P暴露的响应,并应用综合生物标志物响应(IBR)定量评价了Ba P对肝胰脏、肌肉组织的毒性差异。结果显示:肝胰脏、肌肉组织的EROD、GST、SOD、CAT活性整体呈现诱导-抑制的规律性变化,除了0.05μg/L实验组CAT外,其余各实验组肝胰脏组织生物标志物活性在实验结束时均显著高于对照组(P0.05),除了0.45μg/L实验组EROD、CAT外,其余各浓度组肌肉组织生物标志物活性在实验结束时均与对照组无显著性差异(P0.05),MDA含量呈现持续上升的趋势,在实验结束时各实验组均显著高于对照组(P0.05);IBR值存在时间效应和剂量效应。研究结果表明,肝胰脏、肌肉组织对Ba P的暴露响应存在差异性,肝胰脏生物标志物综合应激活性高于肌肉组织。
|
| 关 键 词： | 苯并芘 脊尾白虾 综合生物标志物响应 |
| 收稿时间： | 2017/8/30 0:00:00 |
| 修稿时间： | 2018/1/6 0:00:00 |
INTEGRATED ASSESSMENT OF BIOMARKER RESPONSES IN EXOPALAEMON CARINICAUDA EXPOSED TO BENZO[A]PYRENE |
| |
| LI Lei,LIU Jin-Dian,HUANG Shi-Lin,TANG Feng-Hu,CHEN Yu-Sheng,ZHAO Yong-Chao,XU Cheng-Lin,WANG Yun-Long,SHEN Xin-Qiang and JIANG Mei.INTEGRATED ASSESSMENT OF BIOMARKER RESPONSES IN EXOPALAEMON CARINICAUDA EXPOSED TO BENZO[A]PYRENE[J].Oceanologia Et Limnologia Sinica,2018,49(2):444-451. |
| |
| Authors: | LI Lei LIU Jin-Dian HUANG Shi-Lin TANG Feng-Hu CHEN Yu-Sheng ZHAO Yong-Chao XU Cheng-Lin WANG Yun-Long SHEN Xin-Qiang and JIANG Mei |
| |
| Institution: | Agriculture Ministry Key Laboratory of Healthy Freshwater Aquaculture, Key Laboratory of Fish Health and Nutrition of Zhejiang Province, Zhejiang Institute of Freshwater Fisheries, Huzhou 313001, China;East China Sea Fisheries Research Institute, Chinese Academy of Fishery Sciences, Shanghai 200090, China,Agriculture Ministry Key Laboratory of Healthy Freshwater Aquaculture, Key Laboratory of Fish Health and Nutrition of Zhejiang Province, Zhejiang Institute of Freshwater Fisheries, Huzhou 313001, China,Ocean and Fishery Management Station of Haiyan County, Jiaxing 314300, China,East China Sea Fisheries Research Institute, Chinese Academy of Fishery Sciences, Shanghai 200090, China,Marine Fisheries Research Institute of Jiangsu, Nantong 226007, China,Marine Fisheries Research Institute of Jiangsu, Nantong 226007, China,Marine Fisheries Research Institute of Jiangsu, Nantong 226007, China,East China Sea Fisheries Research Institute, Chinese Academy of Fishery Sciences, Shanghai 200090, China,East China Sea Fisheries Research Institute, Chinese Academy of Fishery Sciences, Shanghai 200090, China and East China Sea Fisheries Research Institute, Chinese Academy of Fishery Sciences, Shanghai 200090, China |
| |
| Abstract: | |
| |
| Keywords: | benzo[a]pyrene Exopalaemon carinicauda integrated biomarker response |
| 本文献已被 CNKI 等数据库收录！ |
| 点击此处可从《海洋与湖沼》浏览原始摘要信息 |
| 点击此处可从《海洋与湖沼》下载免费的PDF全文 |
|
