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64层螺旋CT评估冠状动脉粥样硬化斑块的临床意义
引用本文:刘超,周选明,龚晓红,陈伦刚.64层螺旋CT评估冠状动脉粥样硬化斑块的临床意义[J].CT理论与应用研究,2010,19(2):105-111.
作者姓名:刘超  周选明  龚晓红  陈伦刚
作者单位:郧阳医学院附属太和医院CT室,湖北,十堰442000
摘    要:目的:探讨64层螺旋CT血管造影评估冠状动脉粥样硬化斑块的临床应用价值。方法:回顾性收集2009年6月至9月62例冠心病患者,根据临床表现分为二组:急性冠脉综合征组和稳定型心绞痛组。经64层螺旋CT血管造影诊断,选择由动脉粥样硬化斑块引起的冠状动脉狭窄≥50%的血管100个节段共100个斑块,通过在轴位、曲面重建、最大密度投影、三维最大密度投影3D-MIP、容积再现5种图像上鉴别不同类型斑块,并测量斑块的CT值。结果:100个粥样斑块以Schroeder的两种评估斑块CT值方法作标准,两种标准的3种斑块分型例数高度一致,同一性100%;在急性冠脉综合征组中非钙化斑块的检出率明显高于稳定型心绞痛组,而稳定型心绞痛组钙化斑块检出率明显高于急性冠脉综合征组,两组在统计学上有显著差别(P0.01)。结论:64层螺旋CT可依据斑块的CT值不同判断斑块的性质,可以早期检测不稳定斑块,非钙化斑块与冠心病危险性具有明显的正相关性。

关 键 词:冠状动脉  不稳定斑块  X线计算机  体层摄影术

Clinical Significance of Evaluating Coronary Atherosclerotic Plaque with 64-Slice CT
LIU Chao,ZHOU Xuan-ming,GONG Xiao-hong,CHEN Lun-gang.Clinical Significance of Evaluating Coronary Atherosclerotic Plaque with 64-Slice CT[J].Computerized Tomography Theory and Applications,2010,19(2):105-111.
Authors:LIU Chao  ZHOU Xuan-ming  GONG Xiao-hong  CHEN Lun-gang
Institution:LIU Chao,ZHOU Xuan-ming,GONG Xiao-hong,CHEN Lun-gang (CT Department of Taihe Hospital affiliated to Yunyang Medical College,Shiyan 442000,China)
Abstract:Objective: To investigate the clinical application of 64-slice CT angiography in evaluating coronary atherosclerotic plaque. Method: Retrospectively collect 62 patients who diagnosed as coronary artery disease from June to September in 2009 in our hospital and divide them into two groups according to clinical manifestation, ACS (acute coronary syndromes) group and SAP (stable angina pectoris) group. We selected 100 segments in 100 blood vessels of coronary stenos is ( ≥ 50%) caused by atherosclerotic plaque with 64-slice CT angiography and discriminated the types of the plaques through axial view, CPR and MIP and measured the CT value of the plaques. Result: A hundred atherosclerotic plaques were evaluated with Schroeder’s two standards of CT value plaque-judging methods. The numbers of the three kinds of plaques by the two standards are highly accordant with 100% identity. The detection rate of non-calcified plaque in ACS group is apparently greater than in SAP group, and the detection rate of calcified plaque in SAP group is greater than in ACS group. There is statistical difference between the two groups (P 0.01). Conclusion: 64-slice MSCT can evaluate the nature of different types of plaque and detect unstable plaque in early stage. Non-calcified plaque is positively correlated with the risk of coronary artery disease.
Keywords:coronary artery  unstable plaque  X-ray computed  tomography  
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