Enzyme-like activities of algal polysaccharide - cerium complexes |
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Authors: | Wang Dongfeng Sun Jipeng Du Dehong Ye Shen Wang Changhong Zhou Xiaoling Xue Changhu |
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Institution: | 1. Department of Food Science and Engineering, Ocean University of China, Qingdao 266003, P. R. China 2. Reseach Center for Advanced Science and Technology, The University of Tokyo, Takyo, Japan 3. College of Marine Life Science, Ocean University of China, Qingdao 266003, P. R. China |
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Abstract: | Water-soluble algal polysaccharides (APS) (alginic acid, fucoidan and laminaran) possess many pharmacological activities. The results of this study showed that the APS- Ce4+ complexes have some enzyme-like activities. Fucoidan and its complex with Ce4+ have activities similar to those of SOD. The activities of laminaran, alginic acid and their complexes are not measurable. The APS do not show measurable activities in the digestion of plasmid DNA. In contrast, the APS- Ce4+ complexes show these measurable activities under the comparable condition when APS bind Ce4+ and form homogenous solu-tions. The laminaran- Ce4+ complex shows the most obvious activity in the digestion of plasmid DNA, pNPP and chloropy-rifos under neutral conditions. |
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Keywords: | algal polysaccharides complex scavenging O-2 hydrolase mimics |
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