Ganzi loess represents the oldest Tibetan loess, its formation is the key to determining the readjustment of Tibetan atmospheric circulation and the relationship between Tibetan uplift and global climatic change. Detailed magnetostratigraphic study shows that the Ganzi loess was formed at about 1.13 MaBP. It also reveals that there are two notable climatic events occurring in 0.95–0.92 Ma and 0.65–0.5 Ma respectively. The both demonstrate that the Tibetan atmospheric circulation was readjusted and the Tibetan Plateau entered the cryosphere at 21.13 Ma, and the Tibetan glaciation might reach its maximum at ～0.65–0.5 Ma.