Enantioselectivity of polychlorinated biphenyl atropisomers in sediment and biota from the Turtle/Brunswick River estuary,Georgia, USA |
| |
| Institution: | 1. Department of Chemistry, University of Alberta, Edmonton, AB, Canada T6G 2G2;2. Mote Marine Laboratory Center for Ecotoxicology, Sarasota, FL 34236, USA;3. Southern California Coastal Water Research Project, Costa Mesa, CA 92626, USA;4. Environmental Studies Program and Department of Chemistry, Richardson College for the Environment, University of Winnipeg, Winnipeg, MB, Canada R3B 2E9;1. Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Prince of Wales Hospital, Hong Kong Special Administrative Region, China;2. Li Ka Shing Institute of Health Sciences, The Chinese University of Hong Kong, Prince of Wales Hospital, Hong Kong Special Administrative Region, China;3. Hong Kong Institute of Diabetes and Obesity, The Chinese University of Hong Kong, Prince of Wales Hospital, Hong Kong Special Administrative Region, China;4. Phase 1 Clinical Trial Centre, The Chinese University of Hong Kong, Prince of Wales Hospital, Hong Kong Special Administrative Region, China;1. Department of Microbiology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, China;2. State Key Laboratory of Emerging Infectious Diseases, The University of Hong Kong, Hong Kong, China;3. Collaborative Innovation Centre for Diagnosis and Treatment of Infectious Diseases, The University of Hong Kong, Hong Kong, China;4. Carol Yu Centre for Infection, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, China;5. Department of Pathology, Pamela Youde Nethersole Eastern Hospital, Hong Kong, China;1. Department of Medicine and Therapeutics, Prince of Wales Hospital, The Chinese University of Hong Kong, Sha Tin, New Territories, Hong Kong SAR, China;2. Li Ka Shing Institute of Health Sciences, The Chinese University of Hong Kong, Sha Tin, New Territories, Hong Kong SAR, China;3. Phase 1 Clinical Trial Center, Prince of Wales Hospital, The Chinese University of Hong Kong, Sha Tin, New Territories, Hong Kong SAR, China;4. Department of Chemical Pathology, Prince of Wales Hospital, The Chinese University of Hong Kong, Sha Tin, New Territories, Hong Kong SAR, China;1. Department of Medicine and Therapeutics, Prince of Wales Hospital, The Chinese University of Hong Kong, Hong Kong, China;2. Hong Kong Institute of Diabetes and Obesity, The Chinese University of Hong Kong, Hong Kong, China;3. Li Ka Shing Institute of Health Sciences, The Chinese University of Hong Kong, Hong Kong, China;4. NHMRC Clinical Trial Centre, Faculty of Medicine and Health, University of Sydney, Australia;5. Chinese University of Hong Kong-Shanghai Jiao Tong University Joint Research Centre in Diabetes Genomics and Precision Medicine, Chinese University of Hong Kong, Hong Kong, China;1. Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Prince of Wales Hospital, Hong Kong Special Administrative Region, China;2. Hong Kong Institute of Diabetes and Obesity, The Chinese University of Hong Kong, Prince of Wales Hospital, Hong Kong Special Administrative Region, China;3. Li Ka Shing Institute of Health Sciences, The Chinese University of Hong Kong, Prince of Wales Hospital, Hong Kong Special Administrative Region, China;4. Phase 1 Clinical Trial Centre, The Chinese University of Hong Kong, Prince of Wales Hospital, Hong Kong Special Administrative Region, China |
| |
| Abstract: | To investigate the potential for enantioselective transformation and accumulation, the enantiomer distributions of seven polychlorinated biphenyl (PCB) atropisomers were measured in the sediment and biota from a sub-tropical estuary heavily contaminated with Aroclor 1268, a technical mixture of highly chlorinated PCB congeners. Enantiomer fractions (EFs) of PCBs 91, 95, 136, 149, 174, 176, and 183 in marsh sediment, invertebrate, forage and predatory fish species, and bottlenose dolphins were determined. Non-racemic EFs greater than 0.75 were found in sediments for PCBs 136 and 174, likely the result of microbial dechlorination. Although enantiomer fractions in grass shrimp (Palaemonetes spp.) mirrored those of sediment, fish species had EFs that differed significantly from sediment or grass shrimp. Similarly, bottlenose dolphins were also found to contain non-racemic quantities of PCBs 91, 136, 174, 176, and 183. Non-racemic EFs in these biota were likely a result of both uptake of non-racemic proportions of PCBs from the diet and enantioselective biotransformation. |
| |
| Keywords: | |
| 本文献已被 ScienceDirect 等数据库收录！ |
|
