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肠管周围爬行脂肪CT值变化对克罗恩活动性的诊断价值
引用本文:高贇,管雪妮,戎兰,周磊,梁宗辉.肠管周围爬行脂肪CT值变化对克罗恩活动性的诊断价值[J].CT理论与应用研究,2019,28(4):477-484.
作者姓名:高贇  管雪妮  戎兰  周磊  梁宗辉
作者单位:上海市静安区中心医院放射科,上海,200040;复旦大学附属华山医院消化科,上海,200040;上海市静安区中心医院消化科,上海,200040
基金项目:上海市静安区医学科研课题《多模态磁共振成像对炎症性肠病活动性的评估研究》(2016MS03);上海市卫计委科研项目《磁共振及其功能成像技术在炎症性肠病活动性评价中的应用研究》(201640064);国家自然科学基金面上项目《基于多模态脑功能磁共振的炎症性肠病脑-肠互动机制研究及诊断模型构建》(81871423)。
摘    要:目的:探讨克罗恩病活动性病变患者系膜根部爬行脂肪CT值变化的特点。方法:选取2016年1月至2019年3月上海市静安区中心医院收治的31例克罗恩病活动期患者为研究对象,同时随机选取年龄、性别相匹配的克罗恩病非活动期患者/健康人群作为对照。收集临床资料包括小肠CT增强检查、小肠镜检查及其病理结果、临床免疫抑制治疗疗效。结果:克罗恩病活动期患者31例(男26例,女5例),对照组31例(男22例,女9例)。与对照组相比,克罗恩病活动期患者系膜根部爬行脂肪密度增高,增强后随时间延长可出现持续轻度强化。结论:克罗恩病病变肠管周围的爬行脂肪于疾病活动期可出现密度增高、持续性强化的特点,因此肠管周围爬行脂肪的CT值变化对克罗恩病的活动性具有诊断价值。 

关 键 词:克罗恩病  活动期  爬行脂肪  CT值变化
收稿时间:2019-05-17

Diagnostic Value of CT Value of Creeping Fat around Intestinal Tube for Crohn's Activity
Institution:1. Department of Radiology, Shanghai Jing'an District Centre Hospital, Shanghai 200040, China;2. Department of Gastroenterology, Shanghai Jing'an District Centre Hospital, Shanghai 200040, China;3. Department of Gastroenterology, Fudan University Huashan Hospital, Shanghai 200040, China;
Abstract:Objective: Investigate the CT value changes of creeping fat around the intestinal segment in Crohn's disease(CD).Methods: From January 2010 to March 2019, 31 patients with active CD(study group) and 31 age and gender matched inactive CD patients/healthy people(control group) were enrolled in the study.The people of study group and control group were tested for CT values of mesentery near the inflammatory intestinal wall, including CT values in plain scan, arterial phase, venous phase and delayed phase.Clinical data including enteroscopy and its pathological results, and clinical immunosuppressive therapy were collected.Results: There were 31 patients(26 males and 5 females) with active Crohn's disease(CD) in the study group.There were 31 patients(22 males and 11 females) in control group.The CT value of creeping fat in patients with Crohn's disease in active stage is higher than that in inactive CD patients/healthy people, and there may be sustained mild enhancement after enhancement over time.Conclusion: The creeping fat along the mesenteric border of bowel inflamed segments of CD can be denser and continuously strengthened during the active stage of the disease, so the change of CT value of the creeping fat around the intestinal tube has diagnostic value for Crohn's disease activity. 
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