| Facile Conversion of Alcohols to Olefins by Tosylation and Subsequent SiO2-promoted β-elimination |
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| 作者姓名： | RUAN Xiaohong SONG Gaopeng ZHANG Yichun LI Yingxia |
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| 作者单位： | Key Laboratory of Marine Drugs of the Ministry of Education of China, School of Pharmacy, Ocean University of China, Qingdao 266003, P. R. China |
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| 基金项目： | This work is supported by the National Basic Research Program of China （2003CB716400）. |
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| 摘 要： | A convenient and effective procedure was developed for the conversion of alcohol to olefin by tosylation and subsequent β-elimination promoted by silica gel in this study. Treatment of the alcohols with p-toluenesulfonyl chloride in pyridine at 0℃ affords tosylates which undergo β-elimination with silica gel in dichloromethane or chloroform at room temperature, yielding olefinswith high productivity.
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| 关 键 词： | 醇类 石蜡 简易转化 甲苯磺酰基化 β-消去反应 二氧化硫 |
| 收稿时间： | 2006-04-13 |
| 修稿时间： | 2006-11-29 |
| 本文献已被 CNKI 维普 SpringerLink 等数据库收录！ |
