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Bromophenols from marine algae with potential anti-diabetic activities
Authors:LIN Xiukun  LIU Ming
Institution:1. Department of Pharmacology, Capital Medical University, Beijing 100069, P.R.China
2. Institute of Oceanology, Chinese Academy of Science, Qingdao 266071, P.R.China
Abstract:Marine algae contain various bromophenols with a variety of biological activities, including antimicrobial, anticancer, and anti-diabetic effects. Here, we briefly review the recent progress in researches on the biomaterials from marine algae, emphasizing the relationship between the structure and the potential anti-diabetic applications. Bromophenols from marine algae display their hyperglycemic effects by inhibiting the activities of protein tyrosine phosphatase 1B, ??-glucosidase, as well as other mechanisms.
Keywords:bromophenols  marine algae  type 2 diabetes mellitus
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