Biomarker responses and genotoxicity in the mud snail (Bullacta exarata) as indicators of coastal contamination |
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| Authors: | An Li-hui Zheng Bing-hui Wang Li-jing Zhang Yan-Qiang Chen Hao Zhao Xing-ru Zhang Lei Lei Kun |
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| Institution: | State Key Laboratory of Environmental Criteria and Risk Assessment, Chinese Research Academy for Environmental Sciences, Beijing 100012, China. anlh@craes.org.cn |
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| Abstract: | In the present study different biomarker responses and genotoxicity were determined in wild mud snails (Bullacta exarata) collected from 3 sampling sites in Bohai Bay in northeastern China, which is a region that is under considerable anthropogenic influence. Significant spatial variability of superoxide dismutase (SOD) and metallothionein (MT)-like proteins were recorded, while glutathione transferase (GST), catalase (CAT), and vitellin-like proteins (Vn's) were not observed. Furthermore, genomic DNA that was amplified with 4 fluorescence-labeled primer pairs showed variable genetic distances among the 3 wild mud snail populations found in Bohai Bay, which may be correlated with differences in the types of environmental genotoxicants, such as heavy metals and polycyclic aromatic hydrocarbons. This multi-biomarker approach provided an improved understanding of the potential toxicological impact of contaminated sediments on benthic organisms. |
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