| Abstract: | In the past chemical, ecological, and toxicological research was carried out in a separate way. Nowadays, more and more studies are undertaken considering these three approaches in an integrated way (triad studies). A sophisticated combination of chemical and biological monitoring and bioassays can improve water quality management of polluted rivers. Application of quantitative structure-activity relationships (QSARs), algorithms for mixture toxicity of known substances, chemical group parameters, and response-oriented sum parameters, may reduce uncertainties in ecotoxicological risk management. |
